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• Tamapin

Tamapin is a toxin from the Indian Red Scorpion (Hottentotta tamulus), which is a selective and potent blocker of SK2 channels. Tamapin is named after

Tamapin

Tamapin

• Hottentotta tamulus

Species of scorpion

proteins. Some major components have been isolated, including the toxin tamapin. Scorpion envenomation with high morbidity and mortality is usually due

Hottentotta tamulus



Hottentotta_tamulus

• SK channel

Protein subfamily of calcium-activated potassium channels

sensitive to blockade by the bee toxin apamin, and the scorpion venoms tamapin and charybdotoxin (ChTx), all via competitive antagonism for access to

SK channel



SK_channel

• Apamin

Chemical compound

generating an action potential. Other toxins that block SK channels are tamapin and scyllatoxin. The kinetics of labeled derivatives of apamin were studied

Apamin



Apamin

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