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Class of chemical compounds
Substituted phenylmorpholines, or substituted phenmetrazines alternatively, are chemical derivatives of 2-phenylmorpholine or of the psychostimulant drug
Substituted_phenylmorpholine
Pharmaceutical compound
2-Phenylmorpholine (code name PAL-632) is the parent compound of the substituted phenylmorpholine class of compounds. Examples of 2-phenylmorpholine derivatives
2-Phenylmorpholine
Class of chemical compounds
methylenedioxyphenethylamine Substituted phenethylamine Substituted phenylmorpholine Substituted tryptamine Laras, Y.; Garino, C.; Dessolin, J.; Weck, C
Substituted_piperazine
RO5166017 List of methylphenidate analogues Substituted benzofuran Substituted cathinone Substituted phenylmorpholine Meschino JA, Poos GI. 2-amino-5,6-dihydro-4H-1
List_of_aminorex_analogues
Chemical class of organic compounds
Arylalkylamine Substituted amphetamine Substituted methylenedioxyphenethylamine Substituted cathinone Substituted phenylmorpholine Substituted methoxyphenethylamine
Substituted_phenethylamine
Chemical compound
Chemically, phenmetrazine is a substituted amphetamine containing a morpholine ring or a substituted phenylmorpholine. Phenmetrazine has been used as
Phenmetrazine
Class of compounds based upon the β-hydroxyamphetamine structure
zilpaterol. Substituted amphetamine Substituted methylenedioxyphenethylamine Substituted cathinone Substituted phenylmorpholine 2Cs, DOx, 25-NB Substituted benzofurans
Substituted β-hydroxyamphetamine
Substituted_β-hydroxyamphetamine
Stimulant designer drug
a recreational designer drug with stimulant effects. It is a substituted phenylmorpholine derivative, closely related to better known drugs such as phenmetrazine
4-Methylphenmetrazine
Chemical compound
a recreational designer drug with stimulant effects. It is a substituted phenylmorpholine derivative, closely related to better known drugs such as phenmetrazine
Methylenedioxyphenmetrazine
Class of psychoactive drugs
amphetamine Substituted benzofuran Substituted benzothiophene Substituted cathinone Substituted phenethylamine Substituted phenylmorpholine Substituted tryptamine
Substituted methylenedioxyphenethylamine
Substituted_methylenedioxyphenethylamine
Class of compounds based upon the amphetamine structure
Substituted phenylmorpholines Substituted methoxyphenethylamine 2Cs, DOx, 4Cs, 25-NB, 3C, scaline, FLY Substituted tryptamines Substituted α-alkyltryptamines
Substituted_amphetamine
Chemical compound
a recreational designer drug with stimulant effects. It is a substituted phenylmorpholine derivative, closely related to better known drugs such as phenmetrazine
3-Chlorophenmetrazine
Class of chemical compounds
The substituted benzothiophenes are a class of chemical compounds based on benzothiophene. They are closely related to the substituted benzofurans, substituted
Substituted_benzothiophene
NSAID analgesic drug
reported to have been abused as a recreational drug in the past. Substituted phenylmorpholine Famprofazone Morforex Seyffart G (1991). Drug dosage in Renal
Morazone
Class of chemical compounds
methylenedioxyphenethylamines Substituted phenethylamines Substituted phenylmorpholines Substituted β-ketotryptamines Structural scheduling of synthetic cannabinoids
Substituted_cathinone
Pharmaceutical compound
4-Phenylpiperidine 2-Methyl-3-phenylpiperidine Phenmetrazine Substituted phenylmorpholine 1-Phenylpiperazine Partial ergoline SKF-89145 SKF-89626 Trachsel
3-Phenylpiperidine
Stimulant designer drug
3-Fluorophenmetrazine (also known as 3-FPM, 3-FPH and PAL-593) is a phenylmorpholine-based stimulant and fluorinated analogue of phenmetrazine that has
3-Fluorophenmetrazine
Class of chemical compounds
Substituted phenethylamine Substituted amphetamine Substituted cathinone Substituted methylenedioxyphenethylamine Substituted benzofuran Substituted 2-aminoindane
Substituted naphthylethylamine
Substituted_naphthylethylamine
psychoactive drugs Substituted amphetamine Substituted cathinone Substituted phenylmorpholine Substituted phenethylamine Substituted tryptamine PiHKAL
List_of_designer_drugs
Pharmaceutical compound
chemical stability due to the acid-sensitive oxazolidine ring. Substituted phenylmorpholine List of aminorex analogues 3-Chlorophenmetrazine 3-Fluorophenmetrazine
4-Methyl-5-phenyl-1,3-oxazolidine
4-Methyl-5-phenyl-1,3-oxazolidine
Robalzotan WAY-100635 UH-301 Head-twitch response Substituted benzofuran Substituted phenylmorpholine List of fentanyl analogues Nichols DE (2018). Chemistry
List of miscellaneous 5-HT2A receptor agonists
List_of_miscellaneous_5-HT2A_receptor_agonists
prototypical D-RAs: Substituted amphetamines Substituted cathinones Substituted phenethylamines Substituted phenylmorpholines Substituted methylenedioxyphenethylamines
List_of_cocaine_analogues
Class of chemical compounds
3C (3C-x), also known as 4-substituted 3,5-dimethoxyamphetamines, substituted 3,4,5-trimethoxyamphetamine (3,4,5-TMA or TMA-1) analogues, or 3C-scalines
3C_(psychedelics)
Class of indoles
Substituted 2-aminoindane Substituted amphetamine Substituted benzofuran Substituted cathinone Substituted methylenedioxyphenethylamine Substituted phenethylamine
Substituted_tryptamine
Pharmaceutical compound
releasing agent (MRA) and monoamine reuptake inhibitor (MRI) of the phenylmorpholine and naphthylaminopropane families related to phenmetrazine. It is an
Naphthylmetrazine
Pharmaceutical compound
Richard Glennon and colleagues by 2004. Substituted phenethylamine § Cyclized phenethylamines Substituted phenylmorpholine LPH-5 2C-B-aminorex 2C-B-3PIP 2C-B-PP
2C-B-morpholine
Class of chemical compounds
effects. The Simple Plant Isoquinolines (2002) Substituted phenethylamine Substituted 3-benzazepine Substituted β-carboline and harmala alkaloid Iboga-type
Substituted tetrahydroisoquinoline
Substituted_tetrahydroisoquinoline
Class of chemical compounds
A scaline, also known as a substituted mescaline analogue and typically but not always a 4-substituted 3,5-dimethoxyphenethylamine, is an analogue of
Scaline
Class of chemical compounds
ASR-2001 (2CB-5PrO)) Scalines (4-substituted 3,5-DMPEAs) (e.g., 4-desoxymescaline (DESOXY; 4-Me-3,5-DMPEA)) Ψ-PEAs (4-substituted 2,6-DMPEAs) (e.g., Ψ-2C-T-4)
Substituted methoxyphenethylamine
Substituted_methoxyphenethylamine
Class of chemical compounds
Phenylisobutylamines/α-ethylphenethylamines α-Propylphenethylamines Phenylmorpholines/phenmetrazines Thiopropamines/thienylaminopropanes Cocaine-type/typical
1,2-Diarylethylamine
Class of chemical compounds
among others. Cyclized phenethylamine Substituted methylenedioxyphenethylamine (MDxx) Substituted benzofuran Substituted α-alkyltryptamine Borax combo Sainsbury
Substituted_2-aminoindane
Class of chemical compounds
4-Substituted-2,5-dimethoxyamphetamines (DOx) is a chemical class of substituted amphetamine derivatives featuring methoxy groups at the 2- and 5- positions
DOx
Index of chemical compounds with the same name
Phenylisobutylamines/α-ethylphenethylamines α-Propylphenethylamines Phenylmorpholines/phenmetrazines Thiopropamines/thienylaminopropanes Cocaine-type/typical
Cycloalkylaminopropane
Class of chemical compounds
Lizard Labs in the 2010s and 2020s. Substituted ergoline Partial lysergamide Substituted tryptamine Substituted phenethylamine Lizard Labs Jamieson CS
Lysergamides
Class of chemical compounds
simplified ibogaine analogue, also known as a substituted 1,2,3,4,5,6-hexahydroazepino[4,5-b]indole (or simply substituted hexahydroazepinoindole), is a derivative
Ibogalog
Index of chemical compounds with the same name
6-TMA; TMA-5) 2,4,6-Trimethoxyamphetamine (2,4,6-TMA; TMA-6; ψ-TMA-2) Substituted methoxyphenethylamine Methoxyamphetamine Dimethoxyamphetamine Tetramethoxyamphetamine
Trimethoxyamphetamine
Chemical compound
Prolintane Rolicyclidine (PCPy) MDPV List of aminorex analogues Substituted phenylmorpholine PubChem. "Cyclopropyl-2 p-chlorophenyl-4 methyl-5 pyrrolidine
Picilorex
physiological pH. List of modafinil analogues List of cocaine analogues Substituted cathinone Klare H, Neudörfl JM, Brandt SD, Mischler E, Meier-Giebing
List of methylphenidate analogues
List_of_methylphenidate_analogues
Chemical compound
behavioral sensitization and leads to excessive alcohol intake in rats. Substituted tetrahydroisoquinoline Norsalsolinol 6-Hydroxydopamine MPTP Rotenone
Salsolinol
Methaqualone and Beyond: Structure–Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3 H )-ones and in Silico Prediction of Putative
List of methaqualone analogues
List_of_methaqualone_analogues
Serotonin receptor agonist
prodrug of norpsilocin. 4-HT, also known as 4-hydroxytryptamine, is a substituted tryptamine derivative. It is a positional isomer of the neurotransmitter
4-Hydroxytryptamine
Index of chemical compounds with the same name
6-Tetramethoxyamphetamine (TeMA-2) 2,3,5,6-Tetramethoxyamphetamine (TeMA-3) Substituted methoxyphenethylamine Methoxyamphetamine Dimethoxyamphetamine Trimethoxyamphetamine
Tetramethoxyamphetamine
Index of chemical compounds with the same name
6-Dimethoxyamphetamine (2,6-DMA; DMA-5) 3,5-Dimethoxyamphetamine (3,5-DMA; DMA-6) Substituted methoxyphenethylamine Methoxyamphetamine Trimethoxyamphetamine Tetramethoxyamphetamine
Dimethoxyamphetamine
Class of chemical compounds
A substituted pyridopyrroloquinoxaline, or more specifically a substituted octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline, also known as a
Pyridopyrroloquinoxaline
Class of chemical compounds
cathinone Substituted methylenedioxyphenethylamine Substituted methoxyphenethylamine Substituted naphthylethylamine Substituted phenethylamine Substituted tryptamine
Substituted_benzofuran
Chemical compound
the human trace amine-associated receptor 1 (TAAR1). Quipazine is a substituted piperazine and quinoline. Quipazine is synthesized by reacting 2-chloroquinoline
Quipazine
Pharmaceutical compound
arylmorpholine and naphthylethylamine families. It is the derivative of 2-phenylmorpholine with a 2-naphthalene ring instead of a phenyl ring. Naphthylmorpholine
Naphthylmorpholine
Family of phenethylamine psychedelics
very small role. The 2C drugs, also known as 4-substituted 2,5-dimethoxyphenethylamines, are substituted phenethylamines and can be thought of as synthetic
2C_(psychedelics)
desoxyscaline, also known as a desoxygenated scaline and a type of 4-substituted 3,5-dimethoxyphenethylamine, is an analogue of the phenethylamine psychedelic
Desoxyscaline
Monoamine neurotransmitter
Some serotonergic psychedelics, like psilocin, DMT, and 5-MeO-DMT, are substituted tryptamines and are very similar in chemical structure to serotonin.
Serotonin
Class of chemical compounds
Substituted arylalkylamines, also alternatively known in many cases as substituted arylethylamines, are a group of chemical compounds. These compounds
Arylalkylamine
Class of chemical compounds
4C (4C-x), also known as 4-substituted 2,5-dimethoxy-α-ethylphenethylamines, is a general name for the family of psychedelic and related phenylisobutylamines
4C_(psychedelics)
Chemical compound
It is structurally related to the substituted amphetamines like amphetamine and to the substituted phenylmorpholines like phenmetrazine. A variety of derivatives
Aminorex
5-Dimethoxy-4-bromophenyl)morpholine 2-Fluorophenmetrazine 2-Methylphenmetrazine 2-Phenylmorpholine 2-Phenyl-3,6-dimethylmorpholine 3-Chlorophenmetrazine (PAL-594) 3-Fluorophenetrazine
Phenylcyclopropylamine
Class of chemical compounds
converted to epinephrine. Various stimulant drugs (such as a number of substituted amphetamines) are catecholamine analogues. Catecholamines have the distinct
Catecholamine
Class of chemical compounds
(AMDA) F (F-1; 5-methoxy-6-APDB) Substituted phenethylamine Substituted amphetamine Substituted benzofuran Substituted methoxyphenethylamine 2C, DOx, 4C
FLY_(psychedelics)
Organic compound with at least one hydroxyl (–OH) group
Zaytsev's rule, which states that the most stable (usually the most substituted) alkene is formed. Tertiary alcohols are eliminated easily at just above
Alcohol_(chemistry)
One of four stable isomers of butanediol
Phenylisobutylamines/α-ethylphenethylamines α-Propylphenethylamines Phenylmorpholines/phenmetrazines Thiopropamines/thienylaminopropanes Cocaine-type/typical
1,4-Butanediol
Organic chemical that functions both as a hormone and a neurotransmitter
The presence of a benzene ring with this amine attachment makes it a substituted phenethylamine, a family that includes numerous psychoactive drugs. Like
Dopamine
Class of chemical compounds
They are positional isomers of the 4-substituted 2,5-dimethoxyphenethylamines (e.g., 2Cs and DOx) and 4-substituted 3,5-dimethoxyphenethylamines (e.g.,
Ψ-PEA
Index of chemical compounds with the same name
N-Alkylamphetamine, or a substituted N-alkylamphetamine, is an amphetamine with an alkyl group at the amine nitrogen and can refer to: N-Methylamphetamine
N-Alkylamphetamine
Chemical compound
5-Dimethoxy-4-bromophenyl)morpholine 2-Fluorophenmetrazine 2-Methylphenmetrazine 2-Phenylmorpholine 2-Phenyl-3,6-dimethylmorpholine 3-Chlorophenmetrazine (PAL-594) 3-Fluorophenetrazine
1-Aminomethylindane
Weight loss medication
stimulant, rewarding, and appetite suppressant effects. Chemically, it is a substituted amphetamine. Phentermine was approved for medical use in the United States
Phentermine
Canadian federal drug regulation act
Phendimetrazine (d-3,4-dimethyl-2-phenylmorpholine) and any salt thereof Phenmetrazine (3-methyl-2-phenylmorpholine) and any salt thereof Pipradrol (α
Controlled Drugs and Substances Act
Controlled_Drugs_and_Substances_Act
Pharmaceutical compound
Prodrugs of SDA and/or related compounds have also been described. Substituted methylenedioxyphenethylamine § Related compounds List of investigational
SDA_(drug)
Chemical compound
compound was first isolated in 1901 and was first synthesized in 1929. Substituted tetrahydroisoquinoline 3,4-Dimethoxyphenethylamine Pachycereus pringlei
Carnegine
Family of serotonergic psychedelics
including: Substituted methoxyphenethylamine 4-Substituted 2,5-dimethoxyphenethylamines (2Cs) 4-Substituted 2,5-dimethoxyamphetamines (DOx) 4-Substituted 2
25-NB
Class of psychoactive drugs that produce empathic experiences
(80%) substituted DOM, while 25INBOMe produced 74% drug-appropriate responding (Gatch et al. 2017). On the other hand, only 25B-NBOMe fully substituted for
Entactogen
Class of chemical compounds
doses. Benzazepine Cyclized phenethylamine Substituted tetrahydroisoquinoline Ibogalog Iboga alkaloid Substituted β-carboline Kawase M, Saito S, Motohashi
Substituted_3-benzazepine
is a tricyclic chemical compound. Derivatives of dibenzodiazepine, or substituted dibenzodiazepines, include the antipsychotic clozapine, the antihistamine
Dibenzodiazepine
Chemical compound
A substituted β-carboline, also known as a substituted 9H-pyrido[3,4-b]indole, is a chemical compound featuring a β-carboline moiety with one or more substitutions
Substituted_β-carboline
Chemical compound
as 5-methoxytryptamine or as 5-hydroxytrypamine O-methyl ether, is a substituted tryptamine and a derivative of serotonin (5-hydroxytryptamine) and precursor
5-Methoxytryptamine
Chemical compound
Tiflorex Tranylcypromine Tyramine Tyrosine Xylopropamine Zylofuramine Phenylmorpholines 3-Fluorophenmetrazine Fenbutrazate Fenmetramide G-130 Manifaxine Morazone
Phenylethylpyrrolidine
Pharmaceutical compound
demethylation of the 4-OCH3 group resulted in complete loss of activity. Substitution of benzyloxy group for the 4-OCH3 group increased the activity. Dopamine
4-O-Desmethylmescaline
Class of drugs
but sometimes with other substitutions. Compounds substituted in the 6-position are less effective, while the 4- or 7-substituted compounds are not analgesically
Nitazenes
Stimulant designer drugs
mephedrene) is a stimulant drug which is a ring-substituted derivative of methiopropamine. It is not a substituted cathinone derivative like mephedrone, as it
5-Methylmethiopropamine
Group of psychoactive drugs
The substituted ethylenedioxyphenethylamines (EDxx) are a small group of psychoactive drugs of the phenethylamine family related to the substituted
Substituted ethylenedioxyphenethylamine
Substituted_ethylenedioxyphenethylamine
Pharmaceutical compound
induction of monoamine release in the HEK293 system have been reported. Substituted β-hydroxyamphetamine Mayer FP, Cintulova D, Pittrich DA, Wimmer L, Luethi
4-Methylephedrine
Tian S, Shui W, Ye N (February 2020). "Identification of Novel 1-O-Substituted Aporphine Analogues as Potent 5-HT2C Receptor Agonists". ACS Chem Neurosci
Noraporphine
Stimulant drug of the phenethylamine class
amphetamine, differing from amphetamine's molecular structure only by the substitution of the methyl group at the alpha position of the side chain with an ethyl
Phenylisobutylamine
Group of alkaloids related to Tabernanthe iboga
iboga-type alkaloids include ibogamine, ibogaine, tabernanthine, and other substituted ibogamines . Ibogaine is a hallucinogen and is referred to as an oneirogen
Iboga-type_alkaloid
Pharmaceutical compound
in the scientific literature, in a conference presentation, by 2024. Substituted methylenedioxyphenethylamine Cyclized phenethylamine List of investigational
APA-01
Amphetamine derivative and stimulant
Lauren (2022). "In vivo Structure-Activity Relationships of Substituted Amphetamines and Substituted Cathinones". ProQuest. Retrieved 5 December 2024. FIGURE
Butylamphetamine
Class of synthetic opioids
Hunger A, Kebrle J, Rossi A, Hoffmann K (1957). "Synthesis of basic substituted, analgesically active benzimidazole derivatives". Experientia. 13 (10):
Benzimidazole_opioids
Chemical compound
PRL-8-53 is a nootropic substituted phenethylamine that has been shown to act as a hypermnesic drug in humans; it was first synthesized by medical chemistry
PRL-8-53
Pharmaceutical compound
Therapeutic Chemistry Laboratory) of the Pasteur Institute in Paris, France. Substituted methoxyphenethylamine Ψ-2C-T-4 (2,6-dimethoxy-4-isopropylthiophenethylamine)
CT-5172
Chemical compound
been patented by Mydecine and given the developmental code name MY400. Substituted benzothiophene 6-MAPBT BK-5-MAPBT 5-MAPDI BK-5-MAPB IBF5MAP MDMA Methamnetamine
5-MAPBT
Pharmaceutical compound
5-Dimethoxy-4-bromophenyl)morpholine 2-Fluorophenmetrazine 2-Methylphenmetrazine 2-Phenylmorpholine 2-Phenyl-3,6-dimethylmorpholine 3-Chlorophenmetrazine (PAL-594) 3-Fluorophenetrazine
EME_(drug)
Group of stereoisomers
releasing agent and hence is an indirectly acting sympathomimetic. It is a substituted phenethylamine and amphetamine. Hydroxyamphetamine appeared to remain
4-Hydroxyamphetamine
Class of chemical compounds
Nor-LSD (disambiguation) Seco-LSD Secoergoline Substituted lysergamide Substituted tryptamine Substituted phenethylamine Shulgin AT (1976). "Psychotomimetic
Partial_lysergamide
Index of chemical compounds with the same name
7-API Indolylethylamine (aminoethylindole) Substituted benzofuran Substituted benzothiophene Substituted methylenedioxyphenethylamine This set index
Aminopropylindole
Class of medications
ring system, TCAs can also be usefully grouped based on the number of substitutions of the side chain amine. These groups include the tertiary amines (imipramine
Tricyclic_antidepressant
Phenethylamine derivative
as β-ketophenethylamine, α-desmethylcathinone, or phenacylamine, is a substituted phenethylamine derivative. It is the phenethylamine homologue of cathinone
2-Aminoacetophenone
Central nervous system stimulant
of metabolic integrity. Methamphetamine belongs to the substituted phenethylamine and substituted amphetamine chemical classes and as a drug acts as a
Methamphetamine
Designer drug of the substituted cathinone class
Ethylpentedrone, and NEP) is a chemical compound and stimulant of the substituted cathinone class. Since the mid-2010s, NEP has been sold online as a designer
N-Ethylpentedrone
Chemical compound
monoamine oxidase A (MAO-A) ((R)-enantiomer Ki = 6 μM), among other actions. Substituted tetrahydroisoquinoline Keeper Trout & friends (2013). Trout's Notes on
Salsolidine
so the compounds with potent opioid activity tend to be those with substituted alpha-methyl benzyl or 3,3-diphenylpropyl chains attached to the piperidine
List_of_orphine_opioids
Book about phenethylamines
Isoquinolines (2002) Substituted phenethylamine (PEA) Substituted amphetamine (AMPH) Substituted methylenedioxyphenethylamine (MDxx) Substituted methoxyphenethylamine
The_Shulgin_Index
Substituted cathinone stimulant drug
3-Fluoro-N-ethylbuphedrone (3F-NEB) is a substituted cathinone derivative with stimulant effects which has been sold as a designer drug. It was first
3F-NEB
Pharmaceutical compound
an isomer of 2,5-dimethoxyamphetamine (2,5-DMA). Dimethoxyamphetamine Substituted methoxyphenethylamine 3,4-Methylenedioxyamphetamine (MDA) 3,4-Ethylenedioxyamphetamine
3,4-Dimethoxyamphetamine
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE
SUBSTITUTED PHENYLMORPHOLINE