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The striosomes (also referred to as striatal patches) are one of two complementary chemical compartments within the striatum (the other compartment is
Striosome
Nucleus in the basal ganglia of the brain
the matrix, and the striosome (or patch). The matrix is seen to be rich in acetylcholinesterase, while the embedded striosomes are acetylcholinesterase-poor
Striatum
Bilateral pathway in the brain
volume in a rat. Although all SNc dopamine cells project to both the striosome (or patch) and matrix neurochemical compartments of the striatum, most
Nigrostriatal_pathway
Group of biological receptors
(μ) MOR OP3 (I) μ1, μ2, μ3 brain cortex (laminae III and IV) thalamus striosomes periaqueductal grey rostral ventromedial medulla spinal cord substantia
Opioid_receptor
Class of opioid peptides
GABA in the inhibitory regulation of NMDA-induced dopamine release in striosome- and matrix-enriched areas of the rat striatum". J. Neurosci. 14 (4):
Dynorphin
Mammalian protein found in Homo sapiens
"Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum". Proc. Natl
Protein_c-Fos
American neuroscientist
they were in fact organized into chemical compartments, which she termed striosomes. Later research revealed links between striosomal abnormalities and neurological
Ann_Graybiel
Part of the nervous system in primates
components of the striatum differentiated by staining – striosomes and a matrix. Striosomes are located in the matrix of the striatum and these contain
Primate_basal_ganglia
Professor of psychology in New Zealand
Roon-Mom; Beth J Synek; Ann M Graybiel; Richard Faull (12 October 2006). "Striosomes and mood dysfunction in Huntington's disease". Brain. 130 (Pt 1): 206–221
Lynette_Tippett
Digital brain atlas and virtual microscope
SK; Trimmer JS; Jones EG (2009). "Complete 3-D visualization of primate striosomes by KChIP1 immunostaining". J Comp Neurol. 514 (5): 507–17. doi:10.1002/cne
BrainMaps
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