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system and serving as the most important organ for immune function. Splenocytes are important components of this lymphatic system, consisting of all
Splenocyte
Species of edible, terrestrial cyanobacterium
inflammatory action of white blood cells, specifically macrophages and splenocytes, in vitro. Calvo-Pérez, Juan Diego; Molinari-Novoa, Eduardo A.; Guiry
Fat_choy
Genus of annual plants
Reem; Carr, Ronald I. (15 September 2010). "Nigella sativa modulates splenocyte proliferation, Th1/Th2 cytokine profile, macrophage function and NK anti-tumor
Nigella
Order of reptiles with a shell
effects by inhibiting iNOS and pro-inflammatory cytokine expressions in splenocytes isolated from BALB/c mice". Journal of Functional Foods. 5 (2): 625–632
Turtle
Phylum of photosynthesising prokaryotes
pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes. Sulfate polysaccharides exhibit immunomodulatory, antitumor, antithrombotic
Cyanobacteria
Conduit between embryo/fetus and the placenta
Vendrame M, et al. (2006). "Cord blood rescues stroke-induced changes in splenocyte phenotype and function". Exp. Neurol. 199 (1): 191–200. doi:10.1016/j
Umbilical_cord
Shield for the ventral and dorsal parts of turtles
effects by inhibiting iNOS and pro-inflammatory cytokine expressions in splenocytes isolated from BALB/c mice". Journal of Functional Foods. 5 (2): 625–632
Turtle_shell
Chemical compound
increased frailty, hair loss, and changes in body weight). Cell cultures of splenocytes (i.e., primarily T cells) from the α-ketoglutarate-fed mice produced
Α-Ketoglutaric_acid
Chemical compound
thunberginol a and related compounds isolated from hydrangeae dulcis folium on splenocyte proliferation activated by mitogens". Bioorganic & Medicinal Chemistry
Thunberginol_A
Method for producing lots of identical antibodies
electroporation, which significantly enhances the immune response. Once splenocytes are isolated from the mammal's spleen, the B cells are fused with immortalised
Hybridoma_technology
Species of virus
Bacteriophages provide regulatory signals in mitogen-induced murine splenocyte proliferation. Cell Mol Biol Lett, 2003. 8(3): p. 699-711. Yu, A. and
Bacteriophage_P2
Species of bacterium
pro-inflammatory cytokines by inhibiting NF-κB pathway in macrophages and splenocytes". Biochimica et Biophysica Acta (BBA) - General Subjects. 1830 (4): 2981–2988
Nostoc_commune
Rodent-borne viral infectious disease
destroy infected cells. Their key experiment involved harvesting of splenocytes containing LCMV-specific cytotoxic T lymphocytes (CTL) from an infected
Lymphocytic_choriomeningitis
Australian virologist (1899–1985)
did find support for Burnet's hypothesis in 1953 when they showed that splenocytes could be engrafted by intravenous infusion into mice in utero or just
Macfarlane_Burnet
Species of bird from the Indian subcontinent
"Melatonin prevents testosterone-induced suppression of immune parameters and splenocyte proliferation in Indian tropical jungle bush quail, Perdicula asiatica"
Jungle_bush_quail
by Michael Loken et al. during a two colour experiment, where mouse splenocytes were stained with fluorescein and rhodamine. When one cell is marked
Compensation_(cytometry)
Technique for assessing cell activity
to NAD(P)H flux. Cells with a low metabolism such as thymocytes and splenocytes reduce very little MTT. In contrast, rapidly dividing cells exhibit high
MTT_assay
Cosmopolitan species of fungus
several tumor cell lines in laboratory tests, and stimulated the growth of splenocytes, thymocytes, and bone marrow cells from mice. The extract also stimulated
Astraeus_hygrometricus
Species of legume
Surinamensis Lectin (CasuL) Does Not Impair the Functionality of Mice Splenocytes, Promoting Cell Signaling and Cytokine Production." Biomedicine & Pharmacotherapy
Calliandra_surinamensis
Mammalian cell culture medium
antigen against which we are interested in isolating an antibody. Once splenocytes are isolated from the mammal, the B cells are fused with HGPRT negative
HAT_medium
Chemical compound
dose or concentration (LD, LC): LC50 (median concentration) 148 μM (in splenocytes) Related compounds Related compounds Xylitol Erythritol tetranitrate
Xylitol_pentanitrate
reconstitution and phenotype Humanized mouse Whole blood, Ficoll-separated PBMC, splenocytes 2012 OMIP-013 13 T-cell differentiation Human PBMC 2012 OMIP-014 12 T-cell
Optimized Multicolor Immunofluorescence Panel
Optimized_Multicolor_Immunofluorescence_Panel
Genomics Technique
initial portion of the protocol consists of methodology adapted from splenocyte isolation and sample clean-up. For VINE-Seq, human brain tissue is initially
VINE-seq
Mammalian protein found in humans
is only expressed on thymocytes in rats (contrast to thymocytes and splenocytes in mice). The third intron of the mouse Thy-1 gene has a 36 base pair
CD90
Chemical compound
suppress the induction of interleukin-2 receptor α chain (CD25) in murine splenocytes". Toxicology. 184 (1): 11–22. doi:10.1016/S0300-483X(02)00442-0. PMID 12505372
Tetrabromobisphenol_A
Pharmaceutical compound
RAW264.7 cells. Lastly. it also suppressed lymphocyte proliferation from splenocytes. All these compounds, TNF-α, nitric oxide and lymphocytes, are all essential
Cynaropicrin
Immune response to nonself antigens from members of the same species
MK, Schwartz RH (1987), Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
Alloimmunity
Chemical compound
nonglycogenic steroid, does not inhibit IFN-gamma production by murine splenocytes". Journal of Interferon & Cytokine Research. 18 (11): 921–5. doi:10.1089/jir
Epiestriol
Taiwanese biotechnologist
research on the mitogenicity of thrombin and surface alterations on mouse splenocytes and also on intercellular LETS glycoprotein matrices. He is also a cell
Chen_Lan-bo
Protein
involved in TNF-alpha-stimulated and Rap1-mediated LFA-1 activation in splenocytes. More generally, cells transfected with M-Ras exhibit dendritic appearances
MRAS
Two large masses of nerve tissue in the upper abdomen
Myriam; Oliveros, Liliana; Aguado, Luis (1999). "Effect of Secretion of Splenocytes after Superior Ovarian Nerve Section on the Ovarian Steroidogenesis"
Celiac_ganglia
Protein-coding gene in the species Homo sapiens
in 246 tissues. Androgen deprivation led to lower expression in mice splenocytes compared to the control. Human dendritic cells infected with Chlamydia
TMED5
Czech immunologist (born 1942)
effect on haematopoietic stem cells in bone marrow in vivo and mouse splenocytes and human peripheral blood lymphocytes in vitro". Biomaterials. 10 (5):
Blanka_Říhová
Protein-coding gene in the species Homo sapiens
fluctuations than other pH sensing GPCRs; indeed, in studies of thymocytes and splenocytes taken from mice deficient in either the G2A or another pH-sensing GPCR
GPR132
Chemical compound
phosphodiesterase inhibitors suppress interleukin-2 release from murine splenocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer".
Piclamilast
Novel gene
linkage to the disease. FGFR1OP2 shows low expression levels in septic splenocytes in Mus musculus. FGFR1OP2 is expressed in fetal reticulocytes but not
FGFR1OP2
Chemical compound
non-toxic in vitro. In both human peripheral blood leukocytes and murine splenocytes, (+)-discodermolide was found to suppress the two-way mixed lymphocyte
Discodermolide
Chemical compound
cinobufagin can stimulate the proliferation of immune cells including splenocytes, peritoneal macrophages, T helper cells and cytotoxic T cells. Additionally
Cinobufagin
Indian molecular biologist and biophysicist
"Elucidation of the mechanism of interaction of sheep spleen galectin-1 with splenocytes and its role in cell–matrix adhesion". Journal of Molecular Recognition
Sunil_Kumar_Podder
Overview article
lymphomyeloid cells. We show here that ex vivo GIFT15 treatment of mouse splenocytes generates suppressive regulatory cells of B cell ontogeny (hereafter
Multiple sclerosis drug pipeline
Multiple_sclerosis_drug_pipeline
Protein
not cause expression within FDC-like cell lines. Expression in mouse splenocytes can be induced by LPS in a similar manner to that of human peripheral
FDC-SP
Indian zoologist
in natural killer cell activity and mitogen responsiveness of murine splenocytes. Cellular Immunology 108, 227–234. Atanu Kumar Pati, Arti Chandrawanshi
Atanu_Kumar_Pati
after intestinal colonization with B. fragilis, IL-23 expression by splenocytes was markedly reduced. These data suggest that PSA secreted by B. fragilis
Microbial symbiosis and immunity
Microbial_symbiosis_and_immunity
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