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Protein-coding gene in the species Homo sapiens
inhibitor 2 is an enzyme inhibitor that in humans is encoded by the SPINT2 gene. SPINT2 is a transmembrane protein with two extracellular Kunitz domains
SPINT2
ITIH2, ITIH3, ITIH4 and one light chain selected from the group AMBP or SPINT2. They function as protease inhibitors. IαI form complexes with hyaluronan
Inter-alpha-trypsin_inhibitor
Medical condition
cell adhesion molecule (EpCAM) on chromosome 2 (2p21) and SPINT2 on chromosome 19. SPINT2 is a Kunitz-type protease inhibitor. The mutation in the EpCAM
Congenital tufting enteropathy
Congenital_tufting_enteropathy
15709 SPINK14 HGNC:33825; Q6IE38 15710 SPINT1 HGNC:11246; O43278 15711 SPINT2 HGNC:11247; O43291 15712 SPINT3 HGNC:11248; P49223 15713 SPINT4 HGNC:16130;
List of human protein-coding genes 7
List_of_human_protein-coding_genes_7
InterPro Domain
include: AMBP, APLP2, APP COL6A3, COL7A1, COL28A1 PAPLN, SPINLW1, SPINT1, SPINT2, SPINT3, SPINT4 TFPI, TFPI2 WFDC6, WFDC8, WFIKKN1, WFIKKN2 Several plant
Kunitz_domain
Mammalian protein found in Homo sapiens
epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma". Cancer Res. 65 (11):
Hepatocyte growth factor receptor
Hepatocyte_growth_factor_receptor
610187; ZFPM2 Diarrhea 3, secretory sodium, congenital, syndromic; 270420; SPINT2 Diarrhea 4, malabsorptive, congenital; 610370; NEUROG3 Diarrhea 5, with
List_of_OMIM_disorder_codes
SPINT2
SPINT2
SPINT2
SPINT2
SPINT2
SPINT2
SPINT2
SPINT2
SPINT2