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Protein-coding gene in the species Homo sapiens
Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene. This intronless gene encodes a member of the group C SOX (SRY-related
SOX11
Medical condition
are also multiple genes mutations associated to this syndrome, including SOX11, ARID2, DPF2, PHF6, SMARCA2, SMARCA4, SMARCB1, SMARCC2, SMARCE1, SOX4. The
Coffin–Siris_syndrome
Protein-coding gene in the species Homo sapiens
Sox11. Sox12-null knockout mice appear normal, unlike Sox4 or Sox11 knockout mice. This probably comes from functional redundancy with Sox4 and Sox11
SOX12
other vertebrates have three members of the SoxC group. The three are Sox4, Sox11, and Sox12. These three are extremely similar to one another, more so than
SoxC_group
Family of transcription factors
and ES cells. Granule cells then differentiate to granule neurons, with Sox11 being involved in this process. It is thought that some Sox genes may be
SOX_gene_family
Protein-coding gene in the species Homo sapiens
UTR with several transcription factor binding sites including a Sox11 binding site. Sox11 is involved in the regulation of many developmental genes. KIAA1257
CFAP92
factor SOX11. What is interesting is that FAM71E2 is expressed higher in the SOX11 depleted cells than the control, even though there are SOX11 transcription
FAM71E2
ENSG00000100146 HMG/Sox Known motif – High-throughput in vitro [842] DAACAWWGVV SOX11 ENSG00000176887 HMG/Sox Known motif – from protein with 100% identical DBD
List of human transcription factors
List_of_human_transcription_factors
Protein-coding gene in the species Homo sapiens
Chan WI, Scotting PJ (May 2002). "Differential expression of SOX4 and SOX11 in medulloblastoma". Journal of Neuro-Oncology. 57 (3): 201–14. doi:10
SOX4
Type of blood cancer
to the S phase in the cell cycle) is classically overexpressed in MCL. SOX11 (a transcription factor controlling genes involved in cell survival) is
Mantle_cell_lymphoma
Indian neuroscientist
NuRD Complex and Regulates Cortical Neuron Subtype Determinants Fezf2 and Sox11 Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control
Shubha_Tole
Protein found in humans
C4orf54 mRNA expression using microarray data on patients with SOX11 depletion. The control has significantly higher expression.
Chromosome 4 open reading frame 54
Chromosome_4_open_reading_frame_54
Medical condition
reactive hyperplasia. The neoplastic lymphocytes usually also express CD20, SOX11, and immunoglobulin D but usually do not express two markers that are commonly
In_situ_lymphoid_neoplasia
transcriptional repressor Function; overlapping binding sequence with KLF9 Sox11 221 - Plus 421 Acts as an activator Function; high coservation ONECUT3 245
TMEM202
Epigenetic phenomenon
possible Sox family member to participate in gene regulation with Oct4 – Sox4, Sox11, and Sox15 also participate, as the Sox protein is redundant throughout
Reprogramming
P57073 15538 SOX9 HGNC:11204; P48436 15539 SOX10 HGNC:11190; P56693 15540 SOX11 HGNC:11191; P35716 15541 SOX12 HGNC:11198; O15370 15542 SOX13 HGNC:11192;
List of human protein-coding genes 7
List_of_human_protein-coding_genes_7
Genetic disease resulting in abnormal formation or function of cilia
GPSM2 C‐like syndrome 605039 ASXL1 Coffin–Siris syndrome 135900 ARID1B, SOX11, ARID2 Cohen syndrome 216550 VPS13B Craniofrontonasal dysplasia 304110 EFNB1
Ciliopathy
Endogenous tag expressed in different cells along neurogenesis and differentiated cells
sFRP-2; GATA-2; SLAIN 1; GCNF/NR6A1; SOX1; GFAP; SOX2; Glut1; SOX9; HOXB1; SOX11; ID2; SOX21; Meteorin; SSEA-1; MSX1; TRAF-4; Musashi-1; Vimentin; Musashi-2;
Neuronal_lineage_marker
Microtubule element of the tubulin family
levels. In neural tissue, constitutive expression is driven by Sox4 and Sox11. In non-neural tissues, regulation is dependent on an E-box site in the
Tubulin_beta-3_chain
Belgian physician
multipotent progenitors express similar genes as breast tissue tumors (e.g. Sox11, Stmn1 and Mdk), showing that reactivation of multipotency is involved in
Cédric_Blanpain
demonstrated that PRC2-mediated H3K27me3 silences stem cell genes like Sox11, thereby enabling progenitors to transition into upper-layer neurons. Additionally
Epigenetic regulation of neurogenesis
Epigenetic_regulation_of_neurogenesis
Damage to nervous tissue
including ASCL1, ATF3, CREB1, HIF1α, JUN, KLF6, KLF7, MYC, SMAD1, SMAD2, SMAD3, SOX11, SRF, STAT3, TP53, and XBP1. Several of these can also boost the regenerative
Nerve_injury
Protein-coding gene in the species Homo sapiens
conditions in vitro. First, the depletion of nervous system transcription factor SOX11 causes a slight increase in NBPF1 expression. Additionally, the inactivation
NBPF1
Medical condition
chromosomes 11 and 14 in >95% of cases and in many cases overexpress the SOX11 transcription factor gene. Testing for the chromosome 11, 14 translocation
Monoclonal B-cell lymphocytosis
Monoclonal_B-cell_lymphocytosis
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