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Human breast cancer cell line
SkBr3 (also known as SK-BR-3) is a human breast cancer cell line isolated by the Memorial Sloan–Kettering Cancer Center in 1970 that is used in therapeutic
SKBR3
Chemical compound
Synthase Inhibition by Amentoflavone Suppresses HER2/neu(erbB2) Oncogene in SKBR3 Human Breast Cancer Cells". Phytother. Res. 27 (5): 713–720. doi:10.1002/ptr
Amentoflavone
Adenocarcinoma Metastasis (pleural effusion) No No No Yes Yes Cellosaurus SkBr3 Invasive ductal carcinoma Metastasis (pleural effusion) No No Yes Yes No
List of breast cancer cell lines
List_of_breast_cancer_cell_lines
Type of keratin found in hair and nails
associated with hair structures, KRT81 expression has been observed in the SKBR3 human breast cancer cell line and metastatic lymph nodes of breast carcinomas
Hair_keratin
Mammalian protein found in humans
CTNNB1 DLG4 Erbin GRB2 HSP90AA1 IL6ST MUC1 PICK1 and PIK3R2 PLCG1 and SHC1 SkBr3 Cell Line, over-expresses HER2 GRCh38: Ensembl release 89: ENSG00000141736
HER2
Chemical compound
Neratinib exerts only a modest effect on HER2 trafficking at IC50 of 6nM in SKBR3 cells. Neratinib is a 4-anilino-3-cyano quinoline derivative. Neratinib
Neratinib
Protein-coding gene in the species Homo sapiens
Copine3 with Jab1 activates downstream ErbB2 signaling and motility in SKBr3 breast cancer cells". Oncol. Rep. 35 (2): 1147–52. doi:10.3892/or.2015.4472
Copine_3
Potential cancer treatment
antibodies (anti-HER2 or anti-IgG) via PEG linkers. After incubation of SKBr3 cancer cells with the gold nanoshells, an 820 nm laser was used to irradiate
Photothermal_therapy
Protein-coding gene in the species Homo sapiens
mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line". Cell. Signal. 21 (6): 892–8. doi:10.1016/j.cellsig
SMAD7
Protein-coding gene in the species Homo sapiens
the knockdown of FFAR4 levels in cultured human MCF-7, MDA-MB-231, and SKBR3 breast cancer cells slowed their proliferation and increased their death
Free_fatty_acid_receptor_4
Protein-coding gene in the species Homo sapiens
SFRP1 expression in these cell lines. A different breast cancer cell line (SKBR3, showed loss of SFRP1 expression without significant methylation of the
Secreted frizzled-related protein 1
Secreted_frizzled-related_protein_1
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