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SATB1

  • SATB1
  • Protein-coding gene in the species Homo sapiens

    SATB1 (special AT-rich sequence-binding protein-1) is a protein which in humans is encoded by the SATB1 gene. It is a dimeric/tetrameric transcription

    SATB1

    SATB1

    SATB1

  • Glucocerebroside
  • Family of lipids

    diseases. The increased glucocerebroside levels is caused by a change in the SATB1-MIR22-GBA pathway, which leads to damage to lysosome and mitochondrial function

    Glucocerebroside

    Glucocerebroside

    Glucocerebroside

  • Kohlschütter–Tönz syndrome
  • Medical condition

    autosomal dominant condition caused by heterozygous missense variants in SATB1. The pedigrees of KTS patients suggest autosomal recessive inheritance.

    Kohlschütter–Tönz syndrome

    Kohlschütter–Tönz syndrome

    Kohlschütter–Tönz_syndrome

  • CUT domain
  • Protein family

    recognition of the matrix attachment region of DNA by transcription factor SATB1". Nucleic Acids Research. 35 (15): 5073–5084. doi:10.1093/nar/gkm504. PMC 1976457

    CUT domain

    CUT domain

    CUT_domain

  • CUTL1
  • Protein-coding gene in the species Homo sapiens

    shown to interact with: CREB binding protein, Retinoblastoma protein, and SATB1 These physical interactions are reported in BioPlex 2.0 MAGEA10 EXT2 RAB30

    CUTL1

    CUTL1

    CUTL1

  • SIN3A
  • Protein-coding gene in the species Homo sapiens

    D, Miyano M, Cai S, Varga-Weisz P, Kohwi-Shigematsu T (October 2002). "SATB1 targets chromatin remodelling to regulate genes over long distances". Nature

    SIN3A

    SIN3A

    SIN3A

  • CHD4
  • Protein-coding gene in humans

    CHD4 has been shown to interact with HDAC1, Histone deacetylase 2, MTA2, SATB1 and Ataxia telangiectasia and Rad3 related. Mutations in this gene have

    CHD4

    CHD4

    CHD4

  • SMARCA5
  • Protein-coding gene in the species Homo sapiens

    SMARCA5 has been shown to interact with RAD21, Histone deacetylase 2, POLE3, SATB1 and BAZ1A. GRCh38: Ensembl release 89: ENSG00000153147 – Ensembl, May 2017

    SMARCA5

    SMARCA5

    SMARCA5

  • POLR2J
  • Protein-coding gene in the species Homo sapiens

    interact with: Apoptosis antagonizing transcription factor, POLR2C, and SATB1. GRCh38: Ensembl release 89: ENSG00000005075 – Ensembl, May 2017 GRCm38:

    POLR2J

    POLR2J

    POLR2J

  • List of human transcription factors
  • Inferred motif from similar protein – In vivo/Misc source [798] GCTGATAACAGV SATB1 ENSG00000182568 CUT; Homeodomain Known motif – In vivo/Misc source [799]

    List of human transcription factors

    List_of_human_transcription_factors

  • Homeobox
  • DNA pattern affecting anatomy development

    SIX3, SIX4, SIX5, SIX6 CUT-class: ONECUT1, ONECUT2, ONECUT3; CUX1, CUX2; SATB1, SATB2; ZF-class: ADNP, ADNP2; TSHZ1, TSHZ2, TSHZ3; ZEB1, ZEB2; ZFHX2, ZFHX3

    Homeobox

    Homeobox

    Homeobox

  • FOXP3
  • Immune response protein

    in cancer development. First, FOXP3 represses expression of HER2, Skp2, SATB1 and MYC oncogenes and induces expression of tumour suppressor genes P21

    FOXP3

    FOXP3

    FOXP3

  • POLR2J2
  • Protein-coding gene in the species Homo sapiens

    Durrin LK, Krontiris TG (2002). "The thymocyte-specific MAR binding protein, SATB1, interacts in vitro with a novel variant of DNA-directed RNA polymerase

    POLR2J2

    POLR2J2

    POLR2J2

  • Sanjeev Galande
  • Indian biologist (born 1967)

    with Gestational Diabetes Mellitus (InDiaGDM), Role of chromatin organizer SATB1 in T cell development and differentiation and The role of Chromatin reorganisers

    Sanjeev Galande

    Sanjeev_Galande

  • HDAC1
  • Protein-coding gene in the species Homo sapiens

    protein, Retinoblastoma-like protein 1, Retinoblastoma-like protein 2, SAP30, SATB1, SIN3A, SIN3B, SPEN, SUDS3, SUV39H1, Sp1 transcription factor, TOP2A, TOP2B

    HDAC1

    HDAC1

    HDAC1

  • GATA3
  • Protein-coding gene in the species Homo sapiens

    of DNase I hypersensitive sites and matrix attachment regions which bind SATB1 and GATA-3". Journal of Immunology. 168 (8): 3915–22. doi:10.4049/jimmunol

    GATA3

    GATA3

    GATA3

  • Psychiatric genetics
  • Research field focused on role of genetics in development of mental disorders

    note the several SNPs within the ESR1, GLRB, MYH15, NTRK2, PDE4B, RBFOX1, SATB1, TMEM132D, and TMEM106B genes, which are linked to anxiety disorders and

    Psychiatric genetics

    Psychiatric_genetics

  • HOXB2
  • Protein-coding gene in humans

    Case SS, Huber P, Lloyd JA (Nov 1999). "The gammaPE complex contains both SATB1 and HOXB2 and has positive and negative roles in human gamma-globin gene

    HOXB2

    HOXB2

    HOXB2

  • MTA2
  • Protein-coding gene in the species Homo sapiens

    shown to interact with: CHD4, HDAC1, HDAC2, MBD3 MTA1, RBBP4, RBBP7, and SATB1. GRCh38: Ensembl release 89: ENSG00000149480 – Ensembl, May 2017 GRCm38:

    MTA2

    MTA2

    MTA2

  • DYNLT3
  • Protein-coding gene in humans

    function as a transcription regulator of Bcl-2 gene through binding to SATB1 in a dynein-independent manner. DYNLT3 has been shown to interact with VDAC1

    DYNLT3

    DYNLT3

    DYNLT3

  • List of human protein-coding genes 7
  • Q6UVJ0 14302 SAT1 HGNC:10540; P21673 14303 SAT2 HGNC:23160; Q96F10 14304 SATB1 HGNC:10541; Q01826 14305 SATB2 HGNC:21637; Q9UPW6 14306 SATL1 HGNC:27992;

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • CHD3
  • Protein-coding gene in humans

    Yasui D, Miyano M, Cai S, Varga-Weisz P, Kohwi-Shigematsu T (Oct 2002). "SATB1 targets chromatin remodelling to regulate genes over long distances". Nature

    CHD3

    CHD3

    CHD3

  • CUX1
  • Animal gene

    Masson JY, and Nepveu A. "Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair". Journal of Biological

    CUX1

    CUX1

  • BAZ1A
  • Protein-coding gene in the species Homo sapiens

    regions of chromatin. BAZ1A has been shown to interact with SMARCA5 and SATB1. Jones MH, Hamana N, Nezu J, Shimane M (Apr 2000). "A novel family of bromodomain

    BAZ1A

    BAZ1A

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Online names & meanings

  • Amitabh | அமிதாப
  • Boy/Male

    Tamil

    Amitabh | அமிதாப

    One with boundless splendor, Incomparable, Glorious

  • Chisloth-tabor
  • Biblical

    Chisloth-tabor

    fears; purity

  • Lore
  • Boy/Male

    Basque, British, English, Italian

    Lore

    Variant of Lora

  • Radomil
  • Boy/Male

    Australian, German, Polish

    Radomil

    Happy Peace

  • Jaycee
  • Boy/Male

    English

    Jaycee

    Phonetic name based on initials.

  • Ittifaq
  • Boy/Male

    Arabic, Muslim

    Ittifaq

    Unity; Friendship; Harmony

  • Mellor
  • Surname or Lastname

    English

    Mellor

    English : habitational name from places in Lancashire, West Yorkshire, and Derbyshire, earlier recorded as Melver, and named from ancient British words that are ancestors of Welsh moel ‘bare’ + bre ‘hill’.

  • Dearan
  • Boy/Male

    Australian, Gaelic

    Dearan

    Great

  • Alzaib
  • Boy/Male

    Arabic

    Alzaib

    Tiger

  • Vedanta
  • Boy/Male

    Hindu, Indian

    Vedanta

    Knowledge of Veda's

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