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S100A9

  • S100A9
  • Protein-coding gene in the species Homo sapiens

    (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans is encoded by the S100A9 gene

    S100A9

    S100A9

    S100A9

  • Calprotectin
  • Protein complex found in mammals

    Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis

    Calprotectin

    Calprotectin

  • S100A8
  • Protein-coding gene in Homo sapiens

    S100A8 gene. It is also known as calgranulin A. The proteins S100A8 and S100A9 form a heterodimer called calprotectin. The protein encoded by this gene

    S100A8

    S100A8

    S100A8

  • Semaglutide
  • Anti-diabetic and anti-obesity medication

    suppresses the expression of neutrophil inflammatory factors like S100A8, S100A9, and CXCL2. Consequently, this lowers the systemic release of inflammatory

    Semaglutide

    Semaglutide

    Semaglutide

  • Faecal calprotectin
  • Measurement of calprotectin protein in stool

    white cell scanning. Calprotectin is a 24 kDa protein dimer of S100A8 and S100A9. The complex accounts for up to 60% of the soluble protein content of the

    Faecal calprotectin

    Faecal_calprotectin

  • Nancy Hogg
  • Immunologist

    kindlin-3. Hogg has also studied the S100A8/S100A9 proteins that constitute 45% of neutrophil cytosolic protein. S100a9 null mice demonstrated that myeloid cells

    Nancy Hogg

    Nancy Hogg

    Nancy_Hogg

  • P-bodies
  • Biomolecular condensates of mRNA and RNA binding proteins found in eukaryotic cells

    ARGI1 No TOP2B TOP2B No APOBEC3F ABC3F No NOP58 NOP58 Yes RPF2 RPF2 No S100A9 S100A9 Yes DDX41 DDX41 No KIF23 KIF23 Yes AZGP1 ZA2G No DDX50 DDX50 Yes SERPINB3

    P-bodies

    P-bodies

  • Calgranulin
  • Protein

    neutrophils. The proteins S100A8 and S100A9 form a heterodimer called calprotectin. S100A8 (calgranulin A) S100A9 (calgranulin B) S100A12 (calgranulin

    Calgranulin

    Calgranulin

    Calgranulin

  • Tasquinimod
  • Chemical compound

    myeloid-derived suppressor cells). It binds to and inhibits the interactions of S100A9, an immunomodulatory protein that promotes tumor development, influences

    Tasquinimod

    Tasquinimod

    Tasquinimod

  • Epidermal differentiation complex
  • Gene complex

    generally associated with abnormal epidermal differentiation. S100A8 and S100A9 (calgranulin A and B, respectively), dimerize to form calprotectin. Calprotectin

    Epidermal differentiation complex

    Epidermal_differentiation_complex

  • Basigin
  • Mammalian protein found in Homo sapiens

    proinflammatory transcripts LGALS3BP and S100A9. Notably, CD147 antibody-mediated blocking significantly reduced the expression of S100A9, and S100A8 on megakaryocytes

    Basigin

    Basigin

    Basigin

  • S100 protein
  • Family of vertebrate proteins involved in cell division and inflammation

    S100A6, S100A7 (psoriasin), S100A7A (koebnerisin), S100A8 (calgranulin A), S100A9 (calgranulin B), S100A10, S100A11, S100A12 (calgranulin C), S100A13, S100A14

    S100 protein

    S100 protein

    S100_protein

  • RAGE (receptor)
  • Protein-coding gene in the species Homo sapiens

    Servi B, Medunjanin S, Tessier PA, Mayer D (January 2006). "S100A8 and S100A9 activate MAP kinase and NF-kappaB signaling pathways and trigger translocation

    RAGE (receptor)

    RAGE (receptor)

    RAGE_(receptor)

  • Urinary cell-free DNA
  • ucfDNA Cancer diagnosis Bladder cancer (TopoIIA) Prostate cancer (TSPAN13:S100A9 ratio, c-Myc, BCAS1, and HER2) Colorectal cancer (KRAS mutations, vimentin)

    Urinary cell-free DNA

    Urinary_cell-free_DNA

  • EF hand
  • Protein helix–loop–helix motif

    RHOT1; RHOT2; RPTN; RYR2; RYR3 S100A1; S100A11; S100A12; S100A6; S100A8; S100A9; S100B; S100G; S100Z; SCAMC-2; SCGN; SCN5A; SDF4; SLC25A12; SLC25A13; SLC25A23;

    EF hand

    EF hand

    EF_hand

  • List of human protein-coding genes 7
  • 14231 S100A7A HGNC:21657; Q86SG5 14232 S100A8 HGNC:10498; P05109 14233 S100A9 HGNC:10499; P06702 14234 S100A10 HGNC:10487; P60903 14235 S100A11 HGNC:10488;

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • Enzo Emanuele
  • Italian pathologist (born 1977)

    (December 2006). "Alterations of circulating endogenous secretory RAGE and S100A9 levels indicating dysfunction of the AGE-RAGE axis in autism". Neuroscience

    Enzo Emanuele

    Enzo Emanuele

    Enzo_Emanuele

  • Skin immunity
  • system is driven in this case by the production of alarmins S100A8 and S100A9 known to elicit microbicidal responses and as potent chemoattractants for

    Skin immunity

    Skin_immunity

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    Translation And Transport Factor S100A7A S100A7A Protein S100-A7A S100A9 S100A9 Protein S100-A9 yes SAFB2 SAFB2 Scaffold attachment factor B2 yes SAMD4A

    Stress granule

    Stress granule

    Stress_granule

  • Yu Myeong-Hee
  • South Korean microbiologist

    Kim, Hoguen; Lee, Cheolju (6 March 2009). "Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer". Journal of Proteome Research

    Yu Myeong-Hee

    Yu_Myeong-Hee

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