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Chemical compound
Rupintrivir (AG-7088, Rupinavir) is a peptidomimetic antiviral drug which acts as a 3C and 3CL protease inhibitor. It was developed for the treatment
Rupintrivir
Genus of viruses (Enterovirus)
picornaviruses, include the following: Rupintrivir is a peptidomimetic drug developed for treatment of rhinovirus infections. Rupintrivir inhibits human rhinovirus
Rhinovirus
Chemical compound
for the replication of the virus responsible for COVID-19. 3CLpro-1 Rupintrivir Yang L, Wang Z (September 2023). "Bench-to-bedside: Innovation of small
Iscartrelvir
Class of enzymes
drug targeting 3C protease is in the market yet, but inhibitors such as rupintrivir and pyrazoles show promising targeting in broad range of picornaviruses
Picornain_3C
Class of enzymes
including CLpro-1, GC376, AG7404, lufotrelvir, nirmatrelvir, ratutrelvir, rupintrivir. The intravenous administered prodrug PF-07304814 (lufotrelvir) entered
3C-like_protease
Chemical compound
3CLpro-1 is an antiviral drug related to rupintrivir which acts as a 3CL protease inhibitor and was originally developed for the treatment of human enterovirus
3CLpro-1
Antiviral drug
coxsackievirus, and also has activity against parechoviruses. Pleconaril Rupintrivir Lentz KN, Smith AD, Geisler SC, Cox S, Buontempo P, Skelton A, DeMartino
Pocapavir
Broad-spectrum antiviral medication
blocking the enzyme's normal function. 3CLpro-1 Carmofur Ebselen GRL-0617 Rupintrivir Theaflavin digallate Paxlovid "Anivive". www.anivive.com. Retrieved 2020-05-14
GC376
Chemical compound
marboxil Favipiravir GC376 GRL-0617 Molnupiravir Remdesivir Ribavirin Rupintrivir S-217622 Triazavirin Hoffman RL, Kania RS, Brothers MA, Davies JF, Ferre
Lufotrelvir
rufinamide (INN) rufloxacin (INN) rufocromomycin (INN) Rum-K rupatadine (INN) rupintrivir (USAN) ruplizumab (INN) rurioctocog alfa pegol (INN) rusalactide (USAN)
List_of_drugs:_Rf–Rz
Chemical compound
Ensitrelvir† Ibuzatrelvir Leritrelvir Lufotrelvir Nirmatrelvir† (+ritonavir)† Rupintrivir Simnotrelvir (+ritonavir†) RNA pol inhibitors CMX521§ Deuremidevir† Favipiravir
Simeprevir
Drug repurposing research related to COVID-19
researched and developed in the laboratory such as CLpro-1, GC376, and Rupintrivir. Coronaviruses species possess an intrinsic resistance to ribavirin.
COVID-19 drug repurposing research
COVID-19_drug_repurposing_research
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