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Medication to promote gastrointestinal emptying
A prokinetic agent (also prokineticin, gastroprokinetic agent, gastrokinetic agent or propulsive) is a type of drug which enhances gastrointestinal motility
Prokinetic_agent
Medical condition
modification, medications to stimulate gastric emptying (including some prokinetic agents), medications to reduce vomiting (including some antiemetics), and
Gastroparesis
Condition of impaired digestion
proton-pump inhibitors (PPIs), H2 receptor antagonists (H2-RAs), prokinetic agents, and antiflatulents. PPIs and H2-RAs are often first-line therapies
Indigestion
Antibiotic medication
(April 1993). "Erythromycin: a motilin agonist and gastrointestinal prokinetic agent". The American Journal of Gastroenterology. 88 (4): 485–90. PMID 8470625
Erythromycin
Medical condition
nutrition. Analgesics, antiemetics, antisecretory, antispasmodics, prokinetic agents, laxatives, or antidiarrheal medications may be used to help manage
Chronic intestinal pseudo-obstruction
Chronic_intestinal_pseudo-obstruction
Gastrointestinal disorder
(EPS). Functional dyspepsia can be managed with medications such as prokinetic agents, fundus-relaxing drugs, centrally acting neuromodulators, and proton
Functional_dyspepsia
Life-threatening response to infection
supplements for a person with sepsis or septic shock. The usage of prokinetic agents such as metoclopramide, domperidone, and erythromycin is recommended
Sepsis
Chemical compound
Itopride (INN; brand name Ganaton) is a prokinetic benzamide derivative. These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic
Itopride
Medical condition
Tanaka, S.; Haruma, K.; Chayama, K. (Apr 2009). "Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract". J Gastroenterol
Spontaneous bacterial peritonitis
Spontaneous_bacterial_peritonitis
Chemical compound
Renzapride is a prokinetic agent and antiemetic which acts as a full 5-HT4 agonist and partial 5-HT3 antagonist. It also functions as a 5-HT2B antagonist
Renzapride
Ulceration of the gastrointestinal tract
helpful in identifying people who are suitable for hospital discharge. Prokinetic agents such as erythromycin and metoclopramide can be given before endoscopy
Peptic_ulcer_disease
Chemical compound
malaise, nausea, diarrhea and sometimes constipation. Unlike some other prokinetic agents, mosapride has little effect on potassium channels, no effect on hERG
Mosapride
Class of drug
for metoclopramide, rectally for domperidone). Prokinetic agents (e.g. domperidone) Anti-cholinergic agents (e.g. orphenadrine) Evidence suggests that opioid-inclusive
Opioid
Chemical compound
dose of the drug should be reduced in case of liver diseases. As a prokinetic agent that increases gastrointestinal motility, cisapride acts as a selective
Cisapride
Medication for pain and fever
in neutralizing it. Kidney failure is also a possible side effect. Prokinetic agents such as metoclopramide accelerate gastric emptying, shorten time (tmax)
Paracetamol
Change in the action or side effects of a drug caused
motility may impact the level of other drugs taken. For example, prokinetic agents increase the intestinal motility, which may cause drugs to go through
Drug_interaction
Pill that dissolves on contact with saliva
may be the use of disintegrating aids, such as crospovidone, and binding agents that aid in mouth feel, such as microcrystalline cellulose. Primarily, ODTs
Orally_disintegrating_tablet
Chemical compound
and the company pursued it as an ideal candidate for a long-term prokinetic agent to treat lower gastrointestinal deficiencies including gastroparesis
Mitemcinal
Drug which blocks dopamine receptors
gastroprokinetic agent and galactagogue. Bromopride binds enteric D2 receptors and also treats gastroparesis. Metoclopramide is an effective antiemetic, prokinetic and
Dopamine_antagonist
Chemical compound
M, Tanaka S, Haruma K, Chayama K (April 2009). "Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract". Journal
Trimebutine
Bleeding in the gastrointestinal tract
ligation, sclerotherapy, and fibrin glue depending on what is found. Prokinetic agents such as erythromycin before endoscopy can decrease the amount of blood
Gastrointestinal_bleeding
Nutrients supporting human health
while drinking or eating) can be reduced by elevating the head, using prokinetic agent, and using a chlorhexidine mouthwash. Although the presence of bowel
Human_nutrition
Long-term coughing
include histamine 2 (H2) blockers, proton pump inhibitors (PPI) and prokinetic agents. This medication tends to show results within two weeks; however six
Chronic_cough
Bleeding of the esophagus, stomach, or upper intestine
in those with upper gastrointestinal bleeding are not well known. Prokinetic agents to empty the stomach such as erythromycin before endoscopy can decrease
Upper gastrointestinal bleeding
Upper_gastrointestinal_bleeding
Chemical compound
S2CID 7298061. Roberts DJ, Banh HL, Hall RI (August 2006). "Use of novel prokinetic agents to facilitate return of gastrointestinal motility in adult critically
Dexloxiglumide
Involuntary contraction of the vocal folds restricting inhalation
production of stomach acids, making reflux fluids less irritant. Prokinetic agents reduce the amount of acid available by stimulating movement in the
Laryngospasm
Chemical compound
Bromopride (INN) is a dopamine antagonist with prokinetic properties widely used as an antiemetic, closely related to metoclopramide. It is not available
Bromopride
Medical symptom
in refractory nausea and vomiting and rescue anti emetic therapy. Prokinetic agents such as metoclopramide Dopamine receptor antagonists such as phenothiazines
Cancer_and_nausea
Chemical compound
derivative (2). Robert M, Salvà M, Segarra R, et al. (July 2007). "The prokinetic cinitapride has no clinically relevant pharmacokinetic interaction and
Cinitapride
British surgeon (1856–1943)
gastrointestinal motility disorder. Medical treatment with laxatives, enemas and prokinetic agents, such as cisapride, does not relieve the burdensome symptoms. Retrograde
Sir William Arbuthnot Lane, 1st Baronet
Sir_William_Arbuthnot_Lane,_1st_Baronet
Anti-nausea group of medications
restrictive program to patients who meet certain requirements. Certain prokinetic drugs such as cisapride, renzapride and metoclopramide, although not 5-HT3
5-HT3_antagonist
Flow of stomach contents into the esophagus
include antacids, H2 receptor blockers, proton pump inhibitors, and prokinetics. In the Western world, between 10 and 20% of the population is affected
Gastroesophageal reflux disease
Gastroesophageal_reflux_disease
Medication
of medications known as dopamine receptor antagonists and works as a prokinetic. In 2012, metoclopramide was one of the top 100 most prescribed medications
Metoclopramide
certain toxicities metoclopramide – potent antiemetic, secondarily as a prokinetic metronidazole – antibiotic against anaerobic bacteria milbemycin oxime
List_of_veterinary_drugs
Dopamine antagonist drug
Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it
Clebopride
Bodily function of expelling intestinal gas from the anus
peristaltic activity in the first few hours after waking or the strong prokinetic effect of rectal distension on the rate of transit of intestinal gas.
Flatulence
Disruption to the propulsive ability of the intestine
injury and ischemia. It is usually treated with aggressive fluid support, prokinetics, and anti-inflammatories. Ileus can also be seen in cats. ICD-10 coding
Ileus
Chemical compound
(Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including
Alizapride
Genetic disorder affecting mostly the lungs
and improve the quality of life. While stool softeners, laxatives, and prokinetics (GI-focused treatments) are often suggested, there is no clear consensus
Cystic_fibrosis
Medical condition
simethicone, an oral anti-foaming agent that helps the body to expel the gas more quickly. Combinations of prokinetics, such as domperidone + metoclopramide
Bloating
Group of autoimmune diseases resulting in abnormal growth of connective tissue
inhibitors, and prostanoids Gastrooesophageal reflux disease with antacids or prokinetics Kidney crises with angiotensin converting enzyme inhibitors and angiotensin
Scleroderma
Infrequent or difficult bowel movements
glycol appears superior to lactulose. Prokinetics may be used to improve gastrointestinal motility. A number of new agents have shown positive outcomes in chronic
Constipation
Peripheral D2 receptor antagonist
(January 2014). "Cardiac safety concerns for domperidone, an antiemetic and prokinetic, and galactogogue medicine" (PDF). Expert Opinion on Drug Safety. 13 (1):
Domperidone
Pharmaceutical compound
SB-207266, a selective 5-HT4 receptor antagonist, confirming that the prokinetic activity is mediated through 5-HT4 receptors. In mice, minesapride at
Minesapride
Mammal parasitic disease
symptomatically, such as by using laxatives for constipation or taking a prokinetic drug like metoclopramide before meals to relieve esophageal symptoms.
Chagas_disease
Syndrome causing muscle loss
Non-steroidal anti-inflammatory drugs Prokinetics Ghrelin and ghrelin receptor agonist Anabolic catabolic transforming agents such as MT-102 Selective androgen
Cachexia
Chemical compound
Analgesics Ethenzamide Salicylamide Antidepressants Moclobemide Antiemetics/Prokinetics Alizapride Batanopride Bromopride Cinitapride Cisapride Clebopride Dazopride
Benzamide
sold by Eli Lilly and company, where dextropropoxyphene is an analgesic agent (Darvon), while levopropoxyphene is an effective antitussive (Novrad). Interestingly
Chiral_switch
Class of drugs for reducing stomach acid
"Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative
Proton-pump_inhibitor
Stomach acid suppressing medication
2 weeks after starting both rabeprazole and domperidone, a prokinetic and antiemetic agent, which resolved after discontinuation of both drugs. Per the
Rabeprazole
Human liver enzyme
selected substrates, inducers and inhibitors of CYP2D6. Where classes of agents are listed, there may be exceptions within the class. Inhibitors of CYP2D6
CYP2D6
Clinical symptom
several days. Use of anti-inflammatory, anti-endotoxin, anti-microbial, and prokinetic drugs are common with this disease. Surgery may be needed to rule out
Horse_colic
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