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Pharmaceutical compound
PP405, or PP-405, is a drug acting as a mitochondrial pyruvate carrier (MPC) inhibitor which is under development for the treatment of alopecia (hair
PP405
Pharmaceutical compound
been believed to be PP405, but PP405 was said not to be JXL069 by Pelage Pharmaceuticals. List of investigational hair loss drugs PP405 JXL082 "Regenerative
JXL069
Pharmaceutical compound
for hair loss. It is related to other drugs in the same series such as PP405, JXL069, and UK-5099 (JXL001). The drug is known to have been sold online
JXL082
Pharmaceutical compound
literature by at least 1975. Analogues of UK-5099 like JXL069, JXL082, and PP405 have been developed. List of investigational hair loss drugs Tavoulari S
UK-5099
Pharmaceutical compound
appear to have been disclosed. List of investigational hair loss drugs PP405 and ABS-201 "RS 5441". AdisInsight. 28 July 2025. Retrieved 22 September
ET-02
Physiological molecule and therapeutic drug
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Hyaluronic_acid
Pharmaceutical compound
disclosed. List of investigational hair loss drugs BAY-1158061 (HMI-115) PP405 and ET-02 (RS-5441) "ABS 201". AdisInsight. 7 October 2025. Retrieved 14
ABS-201
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Monobenzone
Central nervous system stimulant
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Caffeine
Medication for parasite infestations
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Ivermectin
Investigational hair loss drugs
– oral – alopecia areata – sphingosine 1 phosphate receptor antagonist PP405 (PP-405) – topical – alopecia – mitochondrial pyruvate carrier (MPC) inhibitor
List of investigational hair loss drugs
List_of_investigational_hair_loss_drugs
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Hydroquinone
Immunosuppressive drug
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Tacrolimus
Medical condition
intradermal and intramuscular botulinum toxin injections to the scalp. The drug PP405 is a potential treatment which works by stimulating follicular mitochondria
Pattern_hair_loss
Antiandrogen medication
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Finasteride
adaption. MPC inhibitors include drugs like UK-5099 (JXL001), JXL069, and PP405. McCommis, Kyle S.; Finck, Brian N. (15 March 2015). "Mitochondrial pyruvate
Mitochondrial pyruvate carrier
Mitochondrial_pyruvate_carrier
Antiseptic solution
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Povidone-iodine
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Magnesium sulfate (medication)
Magnesium_sulfate_(medication)
Skin disease
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Seborrhoeic_dermatitis
Nonsteroidal anti-inflammatory drug
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Diclofenac
Body hair removal
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Hair_removal
Medication
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Atinvicitinib
Drug used to treat allergic diseases
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Dupilumab
Monoclonal antibody
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Nemolizumab
Antifungal chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Ketoconazole
Medication to treat high blood pressure and alopecia
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Minoxidil
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Calcium_gluconate
Steroidal antiandrogen and antimineralocorticoid
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Spironolactone
Drug or agent applied to the skin to control seborrhea or seborrheic dermatitis
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Anti-seborrheic
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Zinc_pyrithione
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Mequinol
Japanese kuge (court aristocrat) family
History of Japan to 1334. Stanford, California: Stanford University Press. pp405-6ff. Sansom, George (1961). A History of Japan: 1334–1615. Stanford, California:
Saionji_family
Hormone replacement medication
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Dutasteride
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Cromoglicic_acid
Bile acid
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Deoxycholic_acid
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
4-Aminobenzoic_acid
Androgen and anabolic steroid
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Metandienone
Pharmaceutical drug classification
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
ATC_code_D11
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Brimonidine
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Afamelanotide
Antiandrogen medication
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Bicalutamide
Type of medicine which removes warts
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Keratolytic
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Management_of_hair_loss
Class of medications
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
5α-Reductase_inhibitor
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Abrocitinib
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Hydrogen_peroxide
Topical decongestant
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Oxymetazoline
Medication to treat hair loss
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Ritlecitinib
Monoclonal antibody
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Lokivetmab
Medication
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Oclacitinib
Immunosuppressive drug
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Pimecrolimus
Pharmaceutical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
AB-103
Monoclonal antibody
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Lebrikizumab
Quaternary ammonium surfactant and antiseptic agent
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Cetrimide
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Eflornithine
Pharmaceutical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Minoxidil/finasteride
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Crisaborole
American politician
and the Assassination of Lincoln (University Press of Mississippi, 1988), pp405-410 United States Congress. "GORDON, James (id: G000312)". Biographical
James Gordon (Mississippi politician)
James_Gordon_(Mississippi_politician)
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Alitretinoin
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Lithium_succinate
Medication
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Alfatradiol
Pharmaceutical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Finasteride/latanoprost/minoxidil
Finasteride/latanoprost/minoxidil
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Flutamide
Month in 1946
Contemporary History of a National Struggle: 1927–1954 (Rose Dog Books, 2008), pp405–406 Lester H. Brune, Chronological History of U.S. Foreign Relations, Volume
January_1946
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Topilutamide
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Medical_uses_of_bicalutamide
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Oxaceprol
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Pregnenolone_acetate
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Nepidermin
Ecclesiae Hibernicae: The succession of the prelates Volume 1" Cotton, H. pp405 Dublin, Hodges & Smith, 1848-1878 Crockford's Clerical Directory 1908 p81
Archdeacon_of_Limerick
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Sofpironium_bromide
Monoclonal antibody
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Tralokinumab
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Bexlosteride
Month in 1909
and the Assassination of Lincoln (University Press of Mississippi, 1988), pp405–410 "New Senator Once Fugitive", New York Times, December 29, 1909, p1 South
December_1909
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Turosteride
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Setipiprant
Contemporary History of a National Struggle: 1927–1954 (Rose Dog Books, 2008), pp405–406 Nguyen Thi Dinh and Mai Elliott, No Other Road to Take (Cornell University
1946_in_French_Indochina
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Tiratricol
Pharmaceutical drug classification
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
ATC_code_D
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Glycopyrronium_tosylate
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Izonsteride
Chemical compound
Potassium channel openers Minoxidil Others Minoxidil/finasteride Nepidermin PP405 Ritlecitinib Hair growth inhibitors 5α-Reductase inhibitors Dutasteride
Lapisteride
PP405
PP405
PP405
PP405
Girl/Female
Indian
Virtuous, Outstanding, Superior, Cultured and refined
Boy/Male
Muslim
Friend
Boy/Male
American, Australian, British, Christian, English, German, Hebrew, Latin
Ready for Battle; Lion-bold; Noble
Boy/Male
Tamil
To spread in different directions
Boy/Male
Spanish
rules by the spear.
Girl/Female
Indian
Light, Illuminate
Biblical
elevation of the jaw-bone
Girl/Female
Hindu, Indian, Kannada, Marathi, Tamil
A Blessing; Delicate; Special
Girl/Female
Indian
Shining Sun
Boy/Male
Latin
River of sorrow.
PP405
PP405
PP405
PP405
PP405