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Opioid receptor antagonist
β-Naltrexamine, or 6β-naltrexamine, is an opioid receptor antagonist related to naltrexol and naltrexone. It has served as a parent pharmacophore for irreversible
Β-Naltrexamine
Class of drug
Nalorphine Naltrexone Naltriben Naltrindole 6β-Naltrexol-d4 3-Iodobenzoyl Naltrexamine Morphinan dimers Pseudomorphine Naloxonazine Norbinaltorphimine Somniferine
Opioid
Substance that forms a complex with a biomolecule
"Narcotic antagonistic potency of bivalent ligands which contain beta-naltrexamine. Evidence for bridging between proximal recognition sites". Journal of
Ligand_(biochemistry)
Agent in biochemistry
the mu opioid receptors. 6α-naltrexo, 6β-naltrexol, 6β-naloxol, and 6β-naltrexamine acted neutral antagonists regardless of opioid binding and caused significantly
Inverse_agonist
Chemical compound
IBNtxA, or 3-iodobenzoyl naltrexamine, is an atypical opioid analgesic drug derived from naltrexone. In animal studies it produces potent analgesic effects
IBNtxA
Opioid
N-2′-Indolylnaltrexamine (INTA) is an opioid and derivative of β-naltrexamine. This molecule is loosely derived from the classical opioid morphine. This
N-2′-Indolylnaltrexamine
Index of chemical compounds with the same molecular formula
formula C20H26N2O3 (molar mass: 342.439 g/mol) may refer to: Cilostamide Naltrexamine LY-86057 This set index page lists chemical structure articles associated
C20H26N2O3
American medicinal chemist (born 1931)
"Narcotic antagonistic potency of bivalent ligands which contain .beta.-naltrexamine. Evidence for simultaneous occupation of proximal recognition sites"
Philip_S._Portoghese
Chemical compound
but also shows some irreversible mixed agonist–antagonist activity. Naltrexamine, an opioid receptor antagonist and the parent compound β-Funaltrexamine
Β-Chlornaltrexamine
MD, Kalyuzhny AE, Roerig SC, Portoghese PS (2011). "N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers"
List_of_opioids
Chemical compound
antagonist of the MOR with no significant opioid agonistic actions. Naltrexamine β-Chlornaltrexamine β-Fuoxymorphamine Manglik A, Kruse AC, Kobilka TS
Β-Funaltrexamine
Chemical compound
"Stereoselective synthesis of β-naltrexol, β-naloxol β-naloxamine, β-naltrexamine and related compounds by the application of the mitsunobu reac". Tetrahedron
Naloxol
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