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MODIMELANOTIDE

  • Modimelanotide

    • Chemical compound

    Modimelanotide (INN; development code AP-214, ABT-719, and ZP-1480) is a melanocortinergic peptide drug derived from α-melanocyte-stimulating hormone (α-MSH)

    Modimelanotide

    Modimelanotide

  • Bremelanotide

    • Chemical compound

    the same family as bremelanotide include afamelanotide (NDP-α-MSH), modimelanotide, and setmelanotide. Studies in the early 1960s showed that administration

    Bremelanotide

    Bremelanotide

    Bremelanotide

  • Melanocyte-stimulating hormone

    • Family of peptide hormones and neuropeptides

    Pharmaceuticals and bremelanotide by Palatin Technologies. Others include modimelanotide and setmelanotide. Afamelanotide (brand name Scenesse) has been approved

    Melanocyte-stimulating hormone

    Melanocyte-stimulating_hormone

  • Melanotan II

    • Drug that never made it to the market

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Melanotan II

    Melanotan II

    Melanotan_II

  • Adrenocorticotropic hormone

    • Pituitary hormone

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Adrenocorticotropic hormone

    Adrenocorticotropic hormone

    Adrenocorticotropic_hormone

  • Afamelanotide

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Afamelanotide

    Afamelanotide

    Afamelanotide

  • Volufralin

    • Pharmaceutical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Volufralin

    Volufralin

    Volufralin

  • Semax

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Semax

    Semax

    Semax

  • Melanocortin 1 receptor

    • Protein controlling mammalian coloration

    peptide full agonist Melanotan II - nonselective peptide full agonist Modimelanotide - nonselective peptide full agonist Setmelanotide - nonselective peptide

    Melanocortin 1 receptor

    Melanocortin 1 receptor

    Melanocortin_1_receptor

  • Setmelanotide

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Setmelanotide

    Setmelanotide

    Setmelanotide

  • THIQ

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    THIQ

    THIQ

    THIQ

  • Agouti-signaling protein

    • Protein-coding gene in mammals

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Agouti-signaling protein

    Agouti-signaling protein

    Agouti-signaling_protein

  • Melanocortin

    • Peptides derived from pro-opiomelanocortin

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Melanocortin

    Melanocortin

  • Melanocortin receptor

    • G protein-coupled receptor

    Non-selective α-MSH β-MSH γ-MSH Afamelanotide Bremelanotide Melanotan II Modimelanotide Setmelanotide MC1-selective BMS-470,539 MC4-selective PF-00446687 PL-6983

    Melanocortin receptor

    Melanocortin_receptor

  • SNAP-7941

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    SNAP-7941

    SNAP-7941

    SNAP-7941

  • Atumelnant

    • Pharmaceutical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Atumelnant

    Atumelnant

    Atumelnant

  • PF-00446687

    • Experimental erectile dysfunction drug

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    PF-00446687

    PF-00446687

    PF-00446687

  • Adrenocorticotropic hormone (medication)

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Adrenocorticotropic hormone (medication)

    Adrenocorticotropic hormone (medication)

    Adrenocorticotropic_hormone_(medication)

  • Melanocortin 4 receptor

    • Mammalian protein found in humans

    ACTH. α-MSH β-MSH γ-MSH ACTH Afamelanotide Bremelanotide Melanotan II Modimelanotide Setmelanotide — MC4 receptor agonist which is FDA approved to help with

    Melanocortin 4 receptor

    Melanocortin 4 receptor

    Melanocortin_4_receptor

  • Α-Melanocyte-stimulating hormone

    • Peptide hormone in mammals

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Α-Melanocyte-stimulating hormone

    Α-Melanocyte-stimulating_hormone

  • ACTH receptor

    • Mammalian protein found in humans

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    ACTH receptor

    ACTH receptor

    ACTH_receptor

  • Agouti-related peptide

    • Mammalian protein found in Homo sapiens

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Agouti-related peptide

    Agouti-related peptide

    Agouti-related_peptide

  • BMS-470539

    • Chemical compound

    favorable pharmacodynamic profile. Afamelanotide Bremelanotide Melanotan II Modimelanotide Setmelanotide Kang L, McIntyre KW, Gillooly KM, et al. (October 2006)

    BMS-470539

    BMS-470539

    BMS-470539

  • Β-Melanocyte-stimulating hormone

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Β-Melanocyte-stimulating hormone

    Β-Melanocyte-stimulating hormone

    Β-Melanocyte-stimulating_hormone

  • Bivamelagon

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Bivamelagon

    Bivamelagon

    Bivamelagon

  • PL-6983

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    PL-6983

    PL-6983

  • Γ-Melanocyte-stimulating hormone

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Γ-Melanocyte-stimulating hormone

    Γ-Melanocyte-stimulating_hormone

  • N-Terminal peptide of proopiomelanocortin

    • I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    N-Terminal peptide of proopiomelanocortin

    N-Terminal_peptide_of_proopiomelanocortin

  • Melanocortin 3 receptor

    • Mammalian protein found in humans

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Melanocortin 3 receptor

    Melanocortin 3 receptor

    Melanocortin_3_receptor

  • Alsactide

    • Chemical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Alsactide

    Alsactide

    Alsactide

  • RO-0282425

    • Pharmaceutical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    RO-0282425

    RO-0282425

  • Mifomelatide

    • Pharmaceutical compound

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Mifomelatide

    Mifomelatide

    Mifomelatide

  • Melanocortin 5 receptor

    • Protein found in humans

    I) BMS-470539 Bremelanotide HS-014 HS-024 MSH (α, β, γ) Melanotan II Modimelanotide PL-8177 SHU-8914 SHU-9005 SHU-9119 SNAP-7941 Antagonists ASIP MC2 Agonists

    Melanocortin 5 receptor

    Melanocortin 5 receptor

    Melanocortin_5_receptor

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