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Pharmaceutical compound
ML337 is an experimental drug that acts as a negative allosteric modulator selective for the glutamate receptor mGluR3. It has only moderate potency with
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Mammalian protein found in humans
orthosteric antagonists MGS-0039, HYDIA (both with bicyclo[3.1.0]hexane skeleton) ML337: selective NAM, IC50 = 450 nM for mGluR3, IC50 >30μM for mGluR2 MNI-137:
Metabotropic glutamate receptor 3
Metabotropic_glutamate_receptor_3
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