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Test for potential genotoxic compounds
There is a chance of more than one micronucleus forming when more genetic damage has happened. The micronucleus test is used as a tool for genotoxicity
Micronucleus_test
Small nucleus in the cells of some organisms
catastrophic mutational event called chromothripsis. Many micronucleus assays have been developed to test for the presence of these structures and determine
Micronucleus
Substance that can cause breaks in chromosomes
The micronucleus test is another type of assay that uses gut cells to observe clastogens, and there are a few different types. The micronucleus test on
Clastogen
Concept in toxicology
numerical aberrations of the genetic material. This is similar to the micronucleus test and chromosome aberration assay, which detect structural and numerical
Genotoxicity
Genus of flowering plants in the bean family
making it easy for a micronucleus test of its root tips to recognize genotoxic compounds. A lectin from V. graminea is used to test for the medically significant
Vicia
Chemical stimulant produced by some plants
genotoxicity such as the comet assay, cytokinesis-block micronucleus test and chromosome aberrations test. In humans, this damage can happen in primary parotid
Nicotine
Physical or chemical agent that increases the rate of genetic mutation
chemical. In micronucleus Test, cells are examined for micronuclei, which are fragments or chromosomes left behind at anaphase, and is therefore a test for clastogenic
Mutagen
Set of accepted specifications
OECD Guidelines for the Testing of Chemicals (OECD TG) are a set of internationally accepted specifications for the testing of chemicals decided on by
OECD Guidelines for the Testing of Chemicals
OECD_Guidelines_for_the_Testing_of_Chemicals
Chemical compound
Dunkelberg H. In vitro genotoxicity of polycyclic musk fragrances in the micronucleus test. Mutation Research, 395(2-3), 145-150. Kevekordes S., Mersch-Sundermann
Cashmeran
Genotoxic assay in fruit fly
Assessment of Chios Mastic Oil by the In Vitro Micronucleus Test on Human Lymphocytes and the In Vivo Wing Somatic Test on Drosophila". PLOS ONE. 10 (6) e0130498
Somatic mutation and recombination tests
Somatic_mutation_and_recombination_tests
Chemical compound
analogues 2,6-diaminotoluene and 2,4-diaminotoluene using the rat micronucleus test and rat liver UDS assay". Carcinogenesis. 12 (12): 2233–2237. doi:10
2,4-Diaminotoluene
Chemical compound
Forward- and Reverse-mutation Assays and in the Mouse Bone-marrow Micronucleus Test. University of Kentucky. Corcoran, John W. (6 December 2012). Biosynthesis
Tomaymycin
Mountain range in Italy
In fact the genetic damage observed in studies performed with the micronucleus test applied on wild rodents from the Piana del Garigliano resulted among
Aurunci_Mountains
Chemical compound
743–747. doi:10.1093/mutage/ges041. PMID 22869611. "Genotoxicity: The Micronucleus Test". Crios. Archived from the original on 28 August 2012. Retrieved 19
Cytochalasin_B
or long-term exposure to radiation. The micronucleus test and the premature chromosome condensation (PCC) test are available to measure acute exposure
History of radiation protection
History_of_radiation_protection
Association between obesity and risk of cancer
overweight Italian children as evaluated by the gamma-H2AX focus assay and micronucleus test". FASEB J. 25 (2): 685–93. doi:10.1096/fj.10-168427. PMID 21068397
Obesity_and_cancer
Chemical compound
3'-Dinitrobisphenol A is found to be genotoxic in male ICR mice on a micronucleus test. Its estrogenic potential is not known however it has shown some binding
Dinitrobisphenol_A
Protein-coding gene in the species Homo sapiens
strength, body fat, body length and plasma immunoglobulins, abnormal open field test and modified SHIRPA behaviour, and severe hearing impairment at 13 weeks
GRXCR1
Antiviral drug
found to be mutagenic in in vitro in the Ames test, CHL test, and in vitro in the mice micronucleus test. Azvudine is toxic to the reproductive system
Azvudine
Taxon of protozoans with hair-like organelles called cilia
The latter is generated from the micronucleus by amplification of the genome and heavy editing. The micronucleus passes its genetic material to offspring
Ciliate
Exopolysaccharide
that it was not mutagenic (assessed by the micronucleus test), nor was it genotoxic as assessed by the Ames test and Comet assay. When administered orally
Botryosphaeran
Protein-coding gene in the species Homo sapiens
mutant mice of both sex displayed various abnormalities in a modified SHIRPA test, including abnormal gait, tail dragging and an absence of pinna reflex, a
MYO7A
Herbicide active ingredient
fluchloralin on human lymphocytes in vitro: chromosomal aberration and micronucleus tests". Mutation Research/Genetic Toxicology. 344 (1–2): 69–72. doi:10
Fluchloralin
Chemical compound
aberration assay on human lymphocytes in vitro and the mouse bone marrow micronucleus test in vivo". Environmental and Molecular Mutagenesis. 28 (2): 133–144
Cyclotriol
maintains two distinct nuclear genomes, the micronucleus and the macronucleus. The macronucleus and micronucleus are located in the same cytoplasm, however
Nuclear_dimorphism
Species of fish
Astyanax) Exposed to the Waters of Engano River (Brazil) as Determined by Micronucleus Tests in Erythrocytes". Archives of Environmental Contamination and Toxicology
Astyanax_bimaculatus
Resting or dormant stage of a microorganism
Dinoflagellates: Dinokaryon Dinocyst Theca Ciliates: Cilium Cirrus Macronucleus Micronucleus Apicomplexans: Rhoptry Apicoplast Microneme Rhizaria Phytomyxea Cruciform
Microbial_cyst
Shell-like protective outer covering of organisms
Dinoflagellates: Dinokaryon Dinocyst Theca Ciliates: Cilium Cirrus Macronucleus Micronucleus Apicomplexans: Rhoptry Apicoplast Microneme Rhizaria Phytomyxea Cruciform
Lorica_(biology)
techniques MeSH E05.393.560.150 – comet assay MeSH E05.393.560.598 – micronucleus tests MeSH E05.393.600.300 – dna footprinting MeSH E05.393.620.311 – ligase
List_of_MeSH_codes_(E05)
Cell organelle in a few species
Dinoflagellates: Dinokaryon Dinocyst Theca Ciliates: Cilium Cirrus Macronucleus Micronucleus Apicomplexans: Rhoptry Apicoplast Microneme Rhizaria Phytomyxea Cruciform
Mitosome
Eukaryotes other than animals, plants or fungi
are also diploid, but instead of producing gametes they divide their micronucleus into two haploid nuclei, exchange one of them by conjugation with another
Protist
Mitochondrion-derived organelle
Dinoflagellates: Dinokaryon Dinocyst Theca Ciliates: Cilium Cirrus Macronucleus Micronucleus Apicomplexans: Rhoptry Apicoplast Microneme Rhizaria Phytomyxea Cruciform
Hydrogenosome
American evolutionary biologist
acids. Her studies of the massive rearrangements of the genome in the micronucleus of Oxytricha showed an unsuspected role for non-coding RNA in directing
Laura_Landweber
Unproven hypothesis regarding low doses of ionizing radiation on health
exposed population, including cytogenetic analyses showing increased micronucleus frequencies in peripheral lymphocytes, increases in acentromeric and
Radiation_hormesis
Bosnian public research institute
used tests in research projects of this lab are based on cell culture and include: chromosome aberrations analysis, cytokinesis-block micronucleus cytome
Institute for Genetic Engineering and Biotechnology
Institute_for_Genetic_Engineering_and_Biotechnology
MRI safety and risk factors
genotoxic effect of magnetic resonance negligible? Low persistence of micronucleus frequency in lymphocytes of individuals after cardiac scan". Mutation
Safety of magnetic resonance imaging
Safety_of_magnetic_resonance_imaging
Species of fish
micronuclei in the red blood cells (erythrocytes). The presence of a micronucleus results from a chromosome (or chromosome fragment) that is not carried
Astyanax_altiparanae
Genus of ciliated protists
sexually through conjugation. During fission, it is observed that the micronucleus divides mitotically before the cell separates into daughter cells. Micronuclei
Spirostomum
Basic unit of life forms
pseudopodia. Ciliates have two different sorts of nuclei: a tiny, diploid micronucleus (the "generative nucleus", which carries the germline of the cell), and
Cell_(biology)
Methods that imitate, replicate or use natural processes
functional genes in the macronucleus, and another "encrypted" copy in the micronucleus. Conjugation of two ciliates consists of the exchange of their micronuclear
Natural_computing
Brightfield whole slide imaging, IHC quantitative scoring, Cytokinesis-blocked micronucleus, region of interest annotating and measuring, tissue matching and FISH
Applied_Spectral_Imaging
Genus of single-celled organisms
They have a bigger, non-germline macronucleus and a small, germline micronucleus in each cell at the same time and these two carry out different functions
Tetrahymena
Pressure reduction and its effects during ascent from depth
Command. Van Liew, HD; Conkin, J (14–16 June 2007). "A start toward micronucleus-based decompression models:Altitude decompression". Bethesda, Maryland:
Decompression_(diving)
Medical condition
macronucleus and a micronucleus, and both are usually visible. The macronucleus is large and sausage-shaped while the micronucleus is less prominent.
Balantidiasis
MRI procedure that measures brain activity by detecting associated changes in blood flow
genotoxic effect of magnetic resonance negligible? Low persistence of micronucleus frequency in lymphocytes of individuals after cardiac scan". Mutation
Functional magnetic resonance imaging
Functional_magnetic_resonance_imaging
and facilitating changes in cell shape, as well as in cytokinesis. micronucleus The smaller of the two types of nuclei that occur in pairs in the cells
Glossary of cellular and molecular biology (M–Z)
Glossary_of_cellular_and_molecular_biology_(M–Z)
also seen for the lone lagging sister chromatid, forming a micronucleus. The micronucleus has the capacity to persist in the daughter cell but with abnormal
Anaphase_lag
signatures of radiation exposure in Oreochromis mossambicus using erythrocyte micronucleus cytome assay (EMNCA)". Environmental Science and Pollution Research.
Dicentric_chromosome
Biomedical imaging technology
genotoxic effect of magnetic resonance negligible? Low persistence of micronucleus frequency in lymphocytes of individuals after cardiac scan". Mutat. Res
Cardiac magnetic resonance imaging
Cardiac_magnetic_resonance_imaging
American scientific consulting firm
drinking water concentrations is not genotoxic in the in vivo bone marrow micronucleus or liver unscheduled DNA synthesis assays". Environmental and Molecular
ChemRisk
Processes to develop the skills and knowledge to dive safely underwater
Retrieved 15 June 2008. Van Liew, H.D.; Conkin, J. (2007). A start toward micronucleus-based decompression models:Altitude decompression. Annual Scientific
Diver_training
Chemical compound
; Hamada, S.; et al., Repeated-dose liver and gastrointestinal tract micronucleus assays with CI Solvent Yellow 14 (Sudan I) using young adult rats. Mutation
Sudan_I
Chemical compound
Genotoxic potential was shown in bacteria and mammalian cell system, micronucleus formation occurred in bone marrow cells. Actual cancer incidence increase
Benzotrichloride
Study of microorganisms in soil
systems. They have two types of nuclei in a single cell: the "germinal" micronucleus and the "somatic" macronucleus. Conjugation (isogamy) between two ciliate
Soil_microbiology
mutagenesis assays (Ames Tests), mammalian mutagenesis assays (mouse lymphoma and other tests), DNA damage assays (micronucleus and chromosomal aberration
IIT_Research_Institute
Protein complex
to either the macronucleus (responsible for gene expression) or the micronucleus (responsible for reproduction). Thus, this species has multiple condensin
Condensin
Theoretical modelling of decompression physiology
1 Chpt. 3 Sec. 9.3 Van Liew, H.D.; Conkin, J. (2007). A start toward micronucleus-based decompression models: Altitude decompression. Annual Scientific
Decompression_theory
Retrieved 2016-12-19. "20 Arduino ZERO Dev. Edition available for beta-testing - Join us!". August 2014. Archived from the original on 2017-07-18. Retrieved
List of Arduino boards and compatible systems
List_of_Arduino_boards_and_compatible_systems
Subfield of genetics devoted to the study of microorganisms
cell functions, expressing the genes needed for daily functioning. The micronucleus is the generative, or germline nucleus, containing the genetic material
Microbial_genetics
Eastmond, D. A.; Tucker, J. D. (1 January 2011). "Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human
Breakage-fusion-bridge_cycle
Chemical compound
PMID 12368121. Humpage AR, Fenech M, Thomas P, Falconer IR (December 2000). "Micronucleus induction and chromosome loss in transformed human white cells indicate
Cylindrospermopsin
MICRONUCLEUS TEST
MICRONUCLEUS TEST
Surname or Lastname
Jewish (Ashkenazic)
Jewish (Ashkenazic) : metonymic occupational name for a refiner, from Yiddish test ‘crucible’, ‘melting pot’.English : nickname for someone with a large or otherwise remarkable head, from Old French teste ‘head’.
Girl/Female
Tamil
Pariksha | பரீகà¯à®·à®¾
Test, Exam
Pariksha | பரீகà¯à®·à®¾
Surname or Lastname
English
English : from the New Testament Greek personal name Timotheos, from Greek timē ‘honor’ + theos ‘God’. This was the name of a companion of St. Paul who, according to tradition, was stoned to death for denouncing the worship of Diana in Ephesus. This was not in general use in England as a given name until Tudor times, so, insofar as it is an English surname at all, it is a late formation (e.g. in Wales, where surnames came into use only relatively recently). In America it also represents an adoption of the English given name in place of a cognate in Greek (Timotheou, Timotheopoulos) or any of various other European languages.Irish : adoption of the English personal name as an equivalent of Tumulty.
Surname or Lastname
English
English : from the Middle English vernacular form, Maudeleyn, of the New Testament Greek personal name Magdalēnē. This is a byname, meaning ‘woman from Magdala’ (a village on the Sea of Galilee, deriving its name from Hebrew migdal ‘tower’), denoting the woman cured of evil spirits by Jesus (Luke 8:2), who later became a faithful follower. In Christian folk belief she was generally identified with the repentant sinner who washed Christ’s feet with her tears in Luke 7; hence the name came to be used as a byname for a prostitute, also a tearful woman. The popularity of the personal name increased with the supposed discovery of her relics in the 13th century.
Girl/Female
Tamil
Pareeksha | பரீகà¯à®·à®¾
Test, Exam
Pareeksha | பரீகà¯à®·à®¾
Surname or Lastname
English
English : from the female personal name Isabel(l)(a). This originated as a variant of Elizabeth, a name which owed its popularity in medieval Europe to the fact that it was borne by John the Baptist’s mother. The original form of the name was Hebrew Elisheva ‘my God (is my) oath’; it appears thus in Exodus 6:23 as the name of Aaron’s wife. By New Testament times the second element had been altered to Hebrew shabat ‘rest’, ‘Sabbath’. The form Isabella originated in Spain, the initial syllable being detached because of its resemblance to the definite article el, and the final one being assimilated to the characteristic Spanish feminine ending -ella. The name in this form was introduced to France in the 13th century, being borne by a sister of St. Louis who lived as a nun after declining marriage with the Holy Roman Emperor. Thence it was taken to England, where it achieved considerable popularity as an independent personal name alongside its doublet Elizabeth.
Surname or Lastname
English, Scottish, French, German, Spanish, Portuguese, and Jewish
English, Scottish, French, German, Spanish, Portuguese, and Jewish : from the Hebrew personal name Gavriel ‘God has given me strength’. This was borne by an archangel in the Bible (Daniel 8:16 and 9:21), who in the New Testament announced the impending birth of Jesus to the Virgin Mary (Luke 1:26–38). It has been a comparatively popular personal name in all parts of Europe, among both Christians and Jews, during the Middle Ages and since. Compare Michael and Raphael.
Surname or Lastname
English, French, German, Dutch, Danish, and South Indian
English, French, German, Dutch, Danish, and South Indian : from the medieval personal name, of Biblical origin, from Aramaic t’Åm’a, a byname meaning ‘twin’. It was borne by one of the disciples of Christ, best known for his scepticism about Christ’s resurrection (John 20:24–29). The th- spelling is organic, the initial letter of the name in the Greek New Testament being a theta. The English pronunciation as t rather than th- is the result of French influence from an early date. In Britain the surname is widely distributed throughout the country, but especially common in Wales and Cornwall. The Ukrainian form is Choma.
Boy/Male
Tamil
Rikshit | ரீகà¯à®·à®¿à®¤
Tested one, Proven (son of Abhimanyu)
Rikshit | ரீகà¯à®·à®¿à®¤
Surname or Lastname
English
English : from a personal name that has the same origin as Jacob. However, among English speakers, it is now felt to be a separate name in its own right. This is largely because in the Authorized Version of the Bible (1611) the form James is used in the New Testament as the name of two of Christ’s apostles (James the brother of John and James the brother of Andrew), whereas in the Old Testament the brother of Esau is called Jacob. The form James comes from Latin Jacobus via Late Latin Jac(o)mus, which also gave rise to Jaime, the regular form of the name in Spanish (as opposed to the learned Jacobo). See also Jack and Jackman. This is a common surname throughout the British Isles, particularly in South Wales.
Surname or Lastname
English
English : nickname from Old French testard, a pejorative derivative of teste ‘head’ (see Testa).German : from Latin testa ‘head’, hence a nickname for someone with a large or otherwise remarkable head, or, especially in Bavaria, a topographic name for someone who lived at one end of a village or a row of fields, from the same word.German : metonymic occupational name for a silver smelter, from Bavarian test ‘furnace for refining silver’.
Surname or Lastname
English and Scottish
English and Scottish : from the Middle English personal name Ma(t)thew, vernacular form of the Greek New Testament name Matthias, Matthaios, which is ultimately from the Hebrew personal name Matityahu ‘gift of God’. This was taken into Latin as Mat(t)hias and Matthaeus respectively, the former being used for the twelfth apostle (who replaced Judas Iscariot) and the latter for the author of the first Gospel. In many European languages this distinction is reflected in different surname forms. The commonest vernacular forms of the personal name, including English Matthew, Old French Matheu, Spanish Mateo, Italian Matteo, Portuguese Mateus, Catalan and Occitan Mateu are generally derived from the form Matthaeus. The American surname Matthew has also absorbed European cognates from other languages, including Greek Mathias and Mattheos.It is found as a personal name among Christians in India, and in the U.S. is used as a family name among families from southern India.
Girl/Female
Hindu
Name of An ancient king, Tested one or proven (son of Abhimanyu)
Girl/Female
Hindu
Test, Exam
Boy/Male
Tamil
Parikshit | பரிகà¯à®·à®¿à®¤Â
Name of An ancient king, Tested one or proven (Posthumous son of Abhimanyu, heir of the Pandavas. Pariksit means 'the examiner', as the brahmins said he would come to examine all men in his search for the Supreme Lord)
Parikshit | பரிகà¯à®·à®¿à®¤Â
Surname or Lastname
English, French, German, Dutch, Spanish (Simón), Czech and Slovak (Šimon), Slovenian, Hungarian, and Jewish (Ashkenazic)
English, French, German, Dutch, Spanish (Simón), Czech and Slovak (Å imon), Slovenian, Hungarian, and Jewish (Ashkenazic) : from the personal name, Hebrew Shim‘on, which is probably derived from the verb sham‘a ‘to hearken’. In the Vulgate and in many vernacular versions of the Old Testament, this is usually rendered Simeon. In the Greek New Testament, however, the name occurs as SimÅn, as a result of assimilation to the pre-existing Greek byname SÄ«mÅn (from sÄ«mos ‘snub-nosed’). Both Simon and Simeon were in use as personal names in western Europe from the Middle Ages onward. In Christendom the former was always more popular, at least in part because of its associations with the apostle Simon Peter, the brother of Andrew. In Britain there was also confusion from an early date with Anglo-Scandinavian forms of Sigmund (see Siegmund), a name whose popularity was reinforced at the Conquest by the Norman form Simund.The earliest documented bearer of the surname Simon in New France came from the Saintonge region of France and was in Montreal by 1655. Another, from Paris, is recorded in Quebec City in 1659 with the secondary surname Lapointe.
Girl/Female
Tamil
Parikshith | பரீகà¯à®·à¯€à®¤
Name of An ancient king, Tested one or proven (son of Abhimanyu)
Parikshith | பரீகà¯à®·à¯€à®¤
Surname or Lastname
English, German, French, and Jewish
English, German, French, and Jewish : from the personal name, Hebrew Yosef ‘may He (God) add (another son)’. In medieval Europe this name was borne frequently but not exclusively by Jews; the usual medieval English vernacular form is represented by Jessup. In the Book of Genesis, Joseph is the favorite son of Jacob, who is sold into slavery by his brothers but rises to become a leading minister in Egypt (Genesis 37–50). In the New Testament Joseph is the husband of the Virgin Mary, which accounts for the popularity of the given name among Christians.A bearer of the name Joseph with the secondary surname Langoumois (and therefore presumably from the Angoumois region of France) is documented in Quebec City in 1718.
Boy/Male
Muslim
One who pronounces the testimony of faith
Girl/Female
Hindu
Test, Exam
MICRONUCLEUS TEST
MICRONUCLEUS TEST
Girl/Female
Danish, Hindu, Indian, Sanskrit, Tamil
Body of Water
Surname or Lastname
English (chiefly West Yorkshire)
English (chiefly West Yorkshire) : habitational name from Stead in West Yorkshire, or from some other place taking its name from Old English stede ‘estate’, ‘farm’, ‘place’.English (chiefly West Yorkshire) : from Middle English steed ‘stud horse’, ‘stallion’, applied as a nickname to a lusty person or as an occupational name to someone responsible for looking after stallions.
Boy/Male
Tamil
Dasmaya | தஸà¯à®®à®¾à®¯à®¾
Beautiful
Male
Scottish
Variant spelling of Scottish Gaelic ÃŒomhar, ÃŒOMHAIR means "bow warrior."
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi
One of the Saints
Girl/Female
Assamese, Gujarati, Hindu, Indian, Kannada, Malayalam, Tamil, Traditional
Who can See the Divine Power of a God; Goddess
Girl/Female
Indian
Goddess Lakshmi
Boy/Male
Bengali, Hindu, Indian, Kannada, Tamil
Moon; Handsome
Boy/Male
Arabic, Muslim
Kindness; Blessing; Grace
Girl/Female
Arabic, Muslim
Joyful; Glad
MICRONUCLEUS TEST
MICRONUCLEUS TEST
MICRONUCLEUS TEST
MICRONUCLEUS TEST
MICRONUCLEUS TEST
n.
The quality or state of being testy; fretfulness; petulance.
pl.
of Testudo
n.
An Italian silver coin. The testoon of Rome is worth 1s. 3d. sterling, or about thirty cents.
v. t.
To bear witness to; to support the truth of by testimony; to affirm or declare solemny.
n.
The act of testing or proving; trial; proof.
p. pr. & vb. n.
of Testify
v. t.
To witness; to attest; to prove by testimony.
v. i.
To make a solemn declaration under oath or affirmation, for the purpose of establishing, or making proof of, some fact to a court; to give testimony in a cause depending before a tribunal.
a.
Relating to, or containing, testimony.
a.
A writing or certificate which bears testimony in favor of one's character, good conduct, ability, etc., or of the value of a thing.
pl.
of Testis
adv.
In a testy manner; fretfully; peevishly; with petulance.
n.
A testicle.
n.
Affirmation; declaration; as, these doctrines are supported by the uniform testimony of the fathers; the belief of past facts must depend on the evidence of human testimony, or the testimony of historians.
n.
The operation of refining gold or silver in a test, or cupel; cupellation.
n.
A genus of tortoises which formerly included a large number of diverse forms, but is now restricted to certain terrestrial species, such as the European land tortoise (Testudo Graeca) and the gopher of the Southern United States.
n.
A tester; a sixpence.
pl.
of Testimony
a.
Alt. of Testudinated
v. i.
To make a solemn declaration, verbal or written, to establish some fact; to give testimony for the purpose of communicating to others a knowledge of something not known to them.