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MCM5

  • MCM5
  • Protein-coding gene in humans

    DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene. The protein encoded by this gene is structurally very similar

    MCM5

    MCM5

    MCM5

  • Meier-Gorlin syndrome
  • Medical condition

    ORC3, ORC4, ORC5 and ORC6 genes), CDC6, CDT1, and MCM2-7 (MCM2, MCM3, MCM4, MCM5, MCM6, MCM7). This complex is loaded on so called origins of replication

    Meier-Gorlin syndrome

    Meier-Gorlin syndrome

    Meier-Gorlin_syndrome

  • PABCO Transit
  • Bus operator in Morris County, New Jersey

    Townpath Square (from AM, to PM) Service started in 1980 by Morris County DOT MCM5 (Monday/Wednesday only) Morristown Routes 510, 513, 182, and 46, via Hackettstown

    PABCO Transit

    PABCO Transit

    PABCO_Transit

  • DNA replication
  • Biological process

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    DNA replication

    DNA replication

    DNA_replication

  • Fistulina hepatica
  • Species of fungus

    TaiCOL: t0035691 Boletus hepaticus Wikidata: Q54364263 AusFungi: 60023729 CoL: MCM5 GBIF (old): 7950839 IndexFungorum: 231009 IRMNG: 11076629 MycoBank: 231009

    Fistulina hepatica

    Fistulina hepatica

    Fistulina_hepatica

  • Origin recognition complex
  • Protein family

    Mcm2/Cdc19/Nda1 Mcm2 Mcm2 Mcm3 Mcm3 Mcm3 Mcm3 Cdc54/Mcm4 Cdc21 DPA Mcm4 Cdc46/Mcm5 Mcm5/Nda4 Mcm5 Mcm5 Mcm6 Mcm6/Mis5 Mcm6 Mcm6 Cdc47/Mcm7 Mcm7 Mcm7 mcm7

    Origin recognition complex

    Origin_recognition_complex

  • STAT1
  • Transcription factor and coding gene in humans

    C, GNB2L1, IFNAR2, IRF1, ISGF3G Interleukin 27 receptor, alpha subunit, MCM5, Mammalian target of rapamycin, PIAS1, PRKCD, PTK2, Protein kinase R, STAT2

    STAT1

    STAT1

    STAT1

  • Origin of replication
  • Sequence in a genome

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    Origin of replication

    Origin of replication

    Origin_of_replication

  • Mendham Township, New Jersey
  • Township in Morris County, New Jersey, US

    78, are all accessible nearby. NJ Transit offered service on the MCM4 and MCM5 routes until 2010, when subsidies to the local provider were eliminated as

    Mendham Township, New Jersey

    Mendham Township, New Jersey

    Mendham_Township,_New_Jersey

  • TOM1
  • lysosome for degradation. This gene is localized to 22q13.1, with HMOX1 and MCM5 distally and HMG2L1 proximally positioned. TOM1 has been shown to interact

    TOM1

    TOM1

    TOM1

  • DNA polymerase epsilon
  • Class of enzymes

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    DNA polymerase epsilon

    DNA_polymerase_epsilon

  • MCM2
  • Protein-coding gene in humans

    interact with: AKAP8, Cell division cycle 7-related protein kinase, MCM3, MCM4, MCM5, MCM6, MCM7, ORC1L, ORC2L, ORC4L, ORC5L, and Replication protein A1. Mini

    MCM2

    MCM2

    MCM2

  • Budd Lake, New Jersey
  • Populated place in Morris County, New Jersey, US

    3.9% of those age 65 or over. NJ Transit offers local bus service on the MCM5 route. People who were born in, residents of, or otherwise closely associated

    Budd Lake, New Jersey

    Budd Lake, New Jersey

    Budd_Lake,_New_Jersey

  • POLE4
  • Protein-coding gene in the species Homo sapiens

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    POLE4

    POLE4

    POLE4

  • MCM3
  • Protein-coding gene in humans

    complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetylated by MCM3AP

    MCM3

    MCM3

    MCM3

  • Minichromosome maintenance
  • Protein family

    Among the latter class of origin-specific mutants were mcm1, mcm2, mcm3, mcm5 and mcm10. Later on, others identified Mcm4, Mcm6 and Mcm7 in yeasts and

    Minichromosome maintenance

    Minichromosome maintenance

    Minichromosome_maintenance

  • E2F
  • Family of transcription factors

    and chromosomal replication (replication origin-binding protein HsOrc1 and MCM5). When cells are not proliferating, E2F DNA binding sites contribute to transcriptional

    E2F

    E2F

  • POLE (gene)
  • Protein-coding gene in humans

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    POLE (gene)

    POLE (gene)

    POLE_(gene)

  • Chromosome 22
  • Human chromosome

    encoding enzyme malonyl CoA-acyl carrier protein transacylase, mitochondrial MCM5 MIF MIRLET7BHG: encoding protein MIRLET7B host gene (non-protein coding)

    Chromosome 22

    Chromosome 22

    Chromosome_22

  • Hackettstown, New Jersey
  • Town in Warren County, New Jersey, US

    Direct trains. New Jersey Transit bus service used to be provided on the MCM5 and 973 local routes before they were discontinued. Warren County operates

    Hackettstown, New Jersey

    Hackettstown, New Jersey

    Hackettstown,_New_Jersey

  • Replicon (genetics)
  • DNA region replicating from a single origin

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    Replicon (genetics)

    Replicon_(genetics)

  • Eukaryotic DNA replication
  • DNA replication in eukaryotic organisms

    Mcm2, Mcm3, Mcm4, Mcm5, Mcm6 and Mcm7 form a hexameric complex that has an open-ring structure with a gap between Mcm2 and Mcm5. The assembly of the

    Eukaryotic DNA replication

    Eukaryotic DNA replication

    Eukaryotic_DNA_replication

  • Chester Borough, New Jersey
  • Borough in Morris County, New Jersey, US

    206 intersect. NJ Transit local bus service was provided on the MCM4 and MCM5 routes until June 2010, when NJ Transit pulled the subsidy. Chester House

    Chester Borough, New Jersey

    Chester Borough, New Jersey

    Chester_Borough,_New_Jersey

  • Mount Olive Township, New Jersey
  • Township in Morris County, New Jersey, US

    Midtown Manhattan. NJ Transit local bus service had been offered on the MCM5 route until 2010, when subsidies offered to the local service provider were

    Mount Olive Township, New Jersey

    Mount Olive Township, New Jersey

    Mount_Olive_Township,_New_Jersey

  • Dover, New Jersey
  • Town in Morris County, New Jersey, US

    served by NJ Transit bus routes 875 and 880, replacing service on the MCM2, MCM5, MCM7 and MCM10 routes until June 2010, when NJ Transit eliminated the subsidy

    Dover, New Jersey

    Dover, New Jersey

    Dover,_New_Jersey

  • Chester Township, New Jersey
  • Township in Morris County, New Jersey, US

    in Bedminster. NJ Transit local bus service was provided on the MCM4 and MCM5 routes until June 2010, when NJ Transit pulled the subsidy. People who were

    Chester Township, New Jersey

    Chester Township, New Jersey

    Chester_Township,_New_Jersey

  • Stress granule
  • Cytoplasmic biomolecular condensates of proteins and RNA occurring in cells under stress

    2 MCM4 MCM4 DNA replication licensing factor MCM4 MCM5 MCM5 DNA replication licensing factor MCM5 MCM7 MCM7 DNA replication licensing factor MCM7 yes

    Stress granule

    Stress granule

    Stress_granule

  • Netcong, New Jersey
  • Borough in Morris County, New Jersey, US

    the Morris & Essex Lines. NJ Transit used to provide local service on the MCM5 route. The Morris County Department of Transportation provides bus service

    Netcong, New Jersey

    Netcong, New Jersey

    Netcong,_New_Jersey

  • MCM6
  • Tsuruga H, Nojima H (1999). "Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F". Oncogene. 18 (14):

    MCM6

    MCM6

    MCM6

  • POLD3
  • Protein-coding gene in the species Homo sapiens

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    POLD3

    POLD3

    POLD3

  • Washington Township, Morris County, New Jersey
  • Township in Morris County, New Jersey, US

    Bedminster and Chester townships. NJ Transit offered local bus service on the MCM5 route, which was terminated in 2010 as part of budget cuts. Radio station

    Washington Township, Morris County, New Jersey

    Washington Township, Morris County, New Jersey

    Washington_Township,_Morris_County,_New_Jersey

  • Cell division cycle 7-related protein kinase
  • Protein found in humans

    necessary proteins are in place. CDC7 has been shown to interact with: DBF4, MCM5, MCM4, MCM7, ORC1L, and ORC6L. Inhibitors XL-413 GRCh38: Ensembl release

    Cell division cycle 7-related protein kinase

    Cell division cycle 7-related protein kinase

    Cell_division_cycle_7-related_protein_kinase

  • ORC6
  • Protein-coding gene in the species Homo sapiens

    replication and segregation with cytokinesis. ORC6 has been shown to interact with MCM5, ORC2, Replication protein A1, ORC4, DBF4, ORC3, CDC45-related protein, MCM4

    ORC6

    ORC6

    ORC6

  • MCM7
  • Protein-coding gene in humans

    CDC6, Cell division cycle 7-related protein kinase, DBF4, MCM2, MCM3, MCM4, MCM5, MCM6, MNAT1, ORC1L, ORC2L, ORC3L, ORC5L, Replication protein A1, Retinoblastoma

    MCM7

    MCM7

    MCM7

  • Mine Hill Township, New Jersey
  • Township in Morris County, New Jersey, US

    Station and Hoboken Terminal. NJ Transit offered local bus service on the MCM5 route, which was eliminated in 2010 when subsidies to the local provider

    Mine Hill Township, New Jersey

    Mine Hill Township, New Jersey

    Mine_Hill_Township,_New_Jersey

  • Mendham Borough, New Jersey
  • Borough in Morris County, New Jersey, US

    Route 510 and County Route 525. NJ Transit offered service on the MCM4 and MCM5 routes until 2010, when subsidies to the local provider were eliminated as

    Mendham Borough, New Jersey

    Mendham Borough, New Jersey

    Mendham_Borough,_New_Jersey

  • Rockaway Township, New Jersey
  • Township in Morris County, New Jersey, US

    provided up to 2010 on the MCM10 route. NJ Transit eliminated service on the MCM5 and MCM7 routes as part of budget cuts. Lakeland Bus Lines offers bus service

    Rockaway Township, New Jersey

    Rockaway Township, New Jersey

    Rockaway_Township,_New_Jersey

  • ORC2
  • Protein-coding gene in the species Homo sapiens

    replication. ORC2 has been shown to interact with: CDC6, DBF4, MCM10, MCM2 MCM4, MCM5, MCM6, MCM7, ORC1, ORC3, ORC4, ORC5, ORC6, and Replication protein A1. GRCh38:

    ORC2

    ORC2

    ORC2

  • Mir-885 microRNA precursor family
  • RNA family

    miR-885-5p, including the CDK2 and MCM5 genes encoding cyclin-dependent kinase 2 and mini-chromosome maintenance protein MCM5, and also with several p53 target

    Mir-885 microRNA precursor family

    Mir-885_microRNA_precursor_family

  • List of human protein-coding genes 5
  • HGNC:6945; P25205 9357 MCM3AP HGNC:6946; O60318 9358 MCM4 HGNC:6947; P33991 9359 MCM5 HGNC:6948; P33992 9360 MCM6 HGNC:6949; Q14566 9361 MCM7 HGNC:6950; P33993

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

  • MicroRNA 885
  • Schwab M, Westermann F (June 2011). "MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival". Cell Death Differ

    MicroRNA 885

    MicroRNA 885

    MicroRNA_885

  • POLE2
  • Protein-coding gene in the species Homo sapiens

    ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 Licensing factor Autonomously replicating sequence Single-strand

    POLE2

    POLE2

    POLE2

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