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MAPK14

  • MAPK14
  • Protein-coding gene in the species Homo sapiens

    also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene. MAPK14 encodes p38α mitogen-activated protein kinase (MAPK) which is the

    MAPK14

    MAPK14

    MAPK14

  • MAPKAPK5
  • Human protein-coding gene

    activated through its phosphorylation by MAP kinases, including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat

    MAPKAPK5

    MAPKAPK5

    MAPKAPK5

  • CP-944629
  • Chemical compound

    is thought to have anti-tumor activities. CP-944629 is assumed to be a MAPK14 (mitogen-activated protein kinase 14 (human)) inhibitor and a p38alpha inhibitor

    CP-944629

    CP-944629

    CP-944629

  • MAP2K3
  • Protein-coding gene in the species Homo sapiens

    kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for

    MAP2K3

    MAP2K3

    MAP2K3

  • P38 mitogen-activated protein kinases
  • Protein family

    cellular responses to cytokines and stress. Four p38 MAP kinases, p38-α (MAPK14), -β (MAPK11), -γ (MAPK12 / ERK6), and -δ (MAPK13 / SAPK4), have been identified

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • MTORC1
  • Protein complex

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MTORC1

    MTORC1

    MTORC1

  • Protein kinase domain
  • Protein domain

    MAP4K3 ; MAP4K4 ; MAP4K5 ; MAPK1 ; MAPK10 ; MAPK11 ; MAPK12 ; MAPK13 ; MAPK14 ; MAPK15 ; MAPK3 ; MAPK4 ; MAPK6 ; MAPK7 ; MAPK8 ; MAPK9 ; MAPKAPK2 ; MAPKAPK3 ;

    Protein kinase domain

    Protein kinase domain

    Protein_kinase_domain

  • VRK2
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    VRK2

    VRK2

    VRK2

  • Mitogen-activated protein kinase
  • P38 mitogen-activated protein kinases

    (JNK2) MAPK10 (JNK3) MAPK11 (p38-beta) MAPK12 (p38-gamma) MAPK13 (p38-delta) MAPK14 (p38-alpha) MAPK4 (ERK4: atypical MAPK) MAPK6 (ERK3: atypical MAPK) MAPK15

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • TAB1
  • Protein-coding gene in the species Homo sapiens

    also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition

    TAB1

    TAB1

    TAB1

  • RPS6KA1
  • Enzyme

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    RPS6KA1

    RPS6KA1

    RPS6KA1

  • ACVR1C
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    ACVR1C

    ACVR1C

    ACVR1C

  • IKBKE
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    IKBKE

    IKBKE

    IKBKE

  • AMP-activated protein kinase
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • CHEK1
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    CHEK1

    CHEK1

    CHEK1

  • GRK5
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    GRK5

    GRK5

    GRK5

  • PLK1
  • Mammalian protein found in Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    PLK1

    PLK1

    PLK1

  • HSP90AB1
  • Protein-coding gene in the species Homo sapiens

    from many more families. Examples of HSP90AB1 client proteins are p38MAPK/MAPK14 (mitogen activated protein kinase 14), ERK5 (extracellular regulated kinase

    HSP90AB1

    HSP90AB1

    HSP90AB1

  • Titin
  • Largest known protein in human muscles

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Titin

    Titin

    Titin

  • Activating transcription factor 2
  • Protein-coding gene in the species Homo sapiens

    with C-jun, Casein kinase 2, alpha 1, CREB binding protein, CSNK2A2, JDP2, MAPK14, MAPK8, Mothers against decapentaplegic homolog 3 NCOA6, RUVBL2, UBE2I.

    Activating transcription factor 2

    Activating transcription factor 2

    Activating_transcription_factor_2

  • MAPK11
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MAPK11

    MAPK11

    MAPK11

  • MAP2K4
  • Protein-coding gene in the species Homo sapiens

    environmental stresses or mitogenic stimuli. MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38 are substrates for MAP2K4, but MAPK1/ERK2 and MAPK3/ERK1 are not phosphorylated

    MAP2K4

    MAP2K4

    MAP2K4

  • Far upstream element–binding protein 1
  • Protein-coding gene in the species Homo sapiens

    Far upstream element-binding protein 1 has been shown to interact with MAPK14 and SMN1. FUBP1 gene deletion forms part of the 1p/19q codeletion mutation

    Far upstream element–binding protein 1

    Far upstream element–binding protein 1

    Far_upstream_element–binding_protein_1

  • NUAK1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    NUAK1

    NUAK1

    NUAK1

  • MAST1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MAST1

    MAST1

    MAST1

  • PCTK3
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    PCTK3

    PCTK3

    PCTK3

  • Serine/threonine-specific protein kinase
  • Class of protein kinase enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • PRKACB
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    PRKACB

    PRKACB

    PRKACB

  • Phosphatidylinositol 3-kinase-related kinase
  • Protein family

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • Extracellular signal-regulated kinases
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • P70-S6 Kinase 1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • AKT1
  • Protein-coding gene in humans

    C-Raf, CDKN1B, CHUK GAB2, HSP90AA1, ILK, KRT10, MAP2K4, MAP3K11, MAP3K8, MAPK14, MAPKAPK2, MARK2, MTCP1, MTOR, NPM1, NR4A1, NR3C4, PKN2, PRKCQ, PDPK1, PLXNA1

    AKT1

    AKT1

    AKT1

  • MAP2K6
  • Protein-coding gene in the species Homo sapiens

    activation and apoptosis. MAP2K6 has been shown to interact with TAOK2, ASK1, MAPK14 and MAP3K7. GRCh38: Ensembl release 89: ENSG00000108984 – Ensembl, May 2017

    MAP2K6

    MAP2K6

    MAP2K6

  • BRAF (gene)
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • MAPKAPK2
  • Protein-coding gene in humans

    MAPKAPK2 independent of p38. MAPKAPK2 has been shown to interact with: AKT1, MAPK14, PHC2, and SHC1. RIPK1 GRCh38: Ensembl release 89: ENSG00000162889 – Ensembl

    MAPKAPK2

    MAPKAPK2

    MAPKAPK2

  • CDC25B
  • Protein-coding gene in humans

    transcript variants for this gene exist. CDC25B has been shown to interact with MAPK14, Casein kinase 2, alpha 1, CHEK1, MELK, Estrogen receptor alpha, YWHAB,

    CDC25B

    CDC25B

    CDC25B

  • (Pyruvate, phosphate dikinase) kinase
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    (Pyruvate, phosphate dikinase) kinase

    (Pyruvate,_phosphate_dikinase)_kinase

  • CAMK
  • Enzyme type

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    CAMK

    CAMK

  • Ca2+/calmodulin-dependent protein kinase II
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent_protein_kinase_II

  • NLK
  • Mammalian protein found in Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    NLK

    NLK

    NLK

  • Cyclin-dependent kinase
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • Mir-17 microRNA precursor family
  • Precursor microRNA family

    FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution". Dev Biol. 333 (2): 238–50

    Mir-17 microRNA precursor family

    Mir-17 microRNA precursor family

    Mir-17_microRNA_precursor_family

  • PIK3R4
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    PIK3R4

    PIK3R4

    PIK3R4

  • RPS6KA4
  • Enzyme found in humans

    been thoroughly characterized. RPS6KA4 has been shown to interact with MAPK14. GRCh38: Ensembl release 89: ENSG00000162302 – Ensembl, May 2017 GRCm38:

    RPS6KA4

    RPS6KA4

    RPS6KA4

  • Protein kinase B
  • Set of three serine threonine-specific protein kinases

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • Protein kinase C zeta type
  • Mammalian protein found in Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • CHEK2
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    CHEK2

    CHEK2

    CHEK2

  • Cyclin-dependent kinase 4
  • Human protein

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Cyclin-dependent kinase 4

    Cyclin-dependent kinase 4

    Cyclin-dependent_kinase_4

  • Protein kinase C
  • Family of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Protein kinase C

    Protein_kinase_C

  • Aurora inhibitor
  • Putative drug class for treating cancer

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • C-Jun N-terminal kinases
  • Chemical compounds

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • MAPK1
  • Protein-coding gene in the species Homo sapiens

    interact with: ADAM17, CIITA, DUSP1, DUSP3, ELK1, FHL2, HDAC4, MAP2K1, MAP3K1 MAPK14, MKNK1, MKNK2, Myc, NEK2, PEA15, PTPN7, Phosphatidylethanolamine binding

    MAPK1

    MAPK1

    MAPK1

  • Cyclin-dependent kinase 1
  • Mammalian protein found in Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Cyclin-dependent kinase 1

    Cyclin-dependent kinase 1

    Cyclin-dependent_kinase_1

  • MKNK2
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MKNK2

    MKNK2

    MKNK2

  • IKBKG
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    IKBKG

    IKBKG

    IKBKG

  • MTOR
  • Mammalian protein found in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MTOR

    MTOR

    MTOR

  • CHUK
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    CHUK

    CHUK

    CHUK

  • MAP3K11
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MAP3K11

    MAP3K11

    MAP3K11

  • List of human protein-coding genes 5
  • Q15759 9243 MAPK12 HGNC:6874; P53778 9244 MAPK13 HGNC:6875; O15264 9245 MAPK14 HGNC:6876; Q16539 9246 MAPK15 HGNC:24667; Q8TD08 9247 MAPKAP1 HGNC:18752;

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

  • (Pyruvate, water dikinase) kinase
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    (Pyruvate, water dikinase) kinase

    (Pyruvate,_water_dikinase)_kinase

  • IkappaB kinase
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    IkappaB kinase

    IkappaB_kinase

  • WNK3
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    WNK3

    WNK3

    WNK3

  • Phosphorylase kinase
  • Enzyme involved in glycogenolysis

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Phosphorylase kinase

    Phosphorylase kinase

    Phosphorylase_kinase

  • Myosin light-chain kinase
  • Class of kinase enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Myosin light-chain kinase

    Myosin light-chain kinase

    Myosin_light-chain_kinase

  • Phosphoinositide-dependent kinase-1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent_kinase-1

  • ZFP36L1
  • Protein-coding gene in the species Homo sapiens

    secretory phenotype (SASP) factors. ZFP36L1 has been shown to interact with MAPK14. GRCh38: Ensembl release 89: ENSG00000185650 – Ensembl, May 2017 GRCm38:

    ZFP36L1

    ZFP36L1

    ZFP36L1

  • G protein-coupled receptor kinase 3
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    G protein-coupled receptor kinase 3

    G protein-coupled receptor kinase 3

    G_protein-coupled_receptor_kinase_3

  • CDC25C
  • Protein-coding gene in humans

    nature of many of them is not known. CDC25C has been shown to interact with MAPK14, CHEK1, PCNA, PIN1, PLK3 and NEDD4. Cdc25 GRCh38: Ensembl release 89: ENSG00000158402

    CDC25C

    CDC25C

    CDC25C

  • FASTK
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    FASTK

    FASTK

    FASTK

  • IRAK4
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    IRAK4

    IRAK4

    IRAK4

  • Protein kinase D1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Protein kinase D1

    Protein kinase D1

    Protein_kinase_D1

  • Bone morphogenetic protein receptor, type 1
  • Group of type I transmembrane proteins

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Bone morphogenetic protein receptor, type 1

    Bone_morphogenetic_protein_receptor,_type_1

  • EIF2AK1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    EIF2AK1

    EIF2AK1

    EIF2AK1

  • Wee1
  • Nuclear protein

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Wee1

    Wee1

    Wee1

  • ACVR2B
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    ACVR2B

    ACVR2B

    ACVR2B

  • ACVR1
  • Protein-coding gene

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    ACVR1

    ACVR1

    ACVR1

  • MYLK2
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MYLK2

    MYLK2

    MYLK2

  • Protein kinase A
  • Family of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • Casein kinase 2, alpha 1
  • Protein and coding gene in humans

    C-Fos, C-jun, CDC25B, CHEK1, CREBBP, CSNK2B, DDIT3, FGF1, FGF2, HNRPA2B1 MAPK14, PIN1, PLEKHO1, PTEN, RELA, TAF1, and UBTF. GRCh38: Ensembl release 89:

    Casein kinase 2, alpha 1

    Casein kinase 2, alpha 1

    Casein_kinase_2,_alpha_1

  • MAPK15
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MAPK15

    MAPK15

    MAPK15

  • Phototropin
  • Class of photoreceptor proteins in plants

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Phototropin

    Phototropin

  • IDH3B
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    IDH3B

    IDH3B

    IDH3B

  • MAP3K1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MAP3K1

    MAP3K1

    MAP3K1

  • PRKAG1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    PRKAG1

    PRKAG1

    PRKAG1

  • 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase

    3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)_kinase

  • PRKCH
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    PRKCH

    PRKCH

    PRKCH

  • DUSP1
  • Protein-coding gene in the species Homo sapiens

    regulation of cellular proliferation. DUSP1 has been shown to interact with MAPK14, MAPK1 and MAPK8. GRCh38: Ensembl release 89: ENSG00000120129 – Ensembl

    DUSP1

    DUSP1

    DUSP1

  • CDKL5
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    CDKL5

    CDKL5

    CDKL5

  • DNA-PKcs
  • Protein found in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    DNA-PKcs

    DNA-PKcs

    DNA-PKcs

  • TGF beta receptor
  • Protein family

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    TGF beta receptor

    TGF_beta_receptor

  • MYLK3
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MYLK3

    MYLK3

    MYLK3

  • MAP kinase kinase kinase kinase
  • Family of proteins

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • ACVR1B
  • Protein-coding gene in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    ACVR1B

    ACVR1B

    ACVR1B

  • Protein kinase R
  • Human protein and coding gene

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • Acetate kinase
  • Class of enzymes

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Acetate kinase

    Acetate kinase

    Acetate_kinase

  • Dual specificity protein kinase TTK
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Dual specificity protein kinase TTK

    Dual specificity protein kinase TTK

    Dual_specificity_protein_kinase_TTK

  • Keratin 8
  • Keratin protein in humans

    circulating tumor cells in blood. Keratin 8 has been shown to interact with MAPK14, Pinin and PPL. Immunohistochemistry GRCh38: Ensembl release 89: ENSG00000170421

    Keratin 8

    Keratin 8

    Keratin_8

  • PKMYT1
  • Protein-coding gene in the species Homo sapiens

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    PKMYT1

    PKMYT1

    PKMYT1

  • Calcium/calmodulin-dependent protein kinase type II subunit alpha
  • Protein found in humans

    N-terminal MAPK8 MAPK9 MAPK10 P38 mitogen-activated protein MAPK11 MAPK13 MAPK14 MAP3K (EC 2.7.11.25) MAP kinase kinase kinases MAP3K1 MAP3K2 MAP3K3 MAP3K4

    Calcium/calmodulin-dependent protein kinase type II subunit alpha

    Calcium/calmodulin-dependent protein kinase type II subunit alpha

    Calcium/calmodulin-dependent_protein_kinase_type_II_subunit_alpha

  • Serine protease HTRA2, mitochondrial
  • Enzyme found in humans

    humans and mice. HtrA serine peptidase 2 has been shown to interact with MAPK14, XIAP and BIRC2. GRCh38: Ensembl release 89: ENSG00000115317 – Ensembl,

    Serine protease HTRA2, mitochondrial

    Serine protease HTRA2, mitochondrial

    Serine_protease_HTRA2,_mitochondrial

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