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HPGD

HPGD

Protein-coding gene in humans

symbol = HPGD; HGNC ID, HGNC:5154), also called 15-hydroxyprostaglandin dehydrogenase [NAD+], is an enzyme that in humans is encoded by the HPGD gene. In

HPGD

15-hydroxyprostaglandin dehydrogenase (NAD+)

Class of enzymes

symbol = HPGD; HGNC ID, HGNC:5154), also called 15-hydroxyprostaglandin dehydrogenase (NAD+), (EC 1.1.1.141), is an enzyme produced by the HPGD gene. It

15-hydroxyprostaglandin dehydrogenase (NAD+)

15-hydroxyprostaglandin_dehydrogenase_(NAD+)

Nail clubbing

Deformity of the finger or toe nails

(4q33-q34) coding for the enzyme 15-hydroxyprostaglandin dehydrogenase (HPGD); this leads to decreased breakdown of prostaglandin E2 and elevated levels

Nail clubbing

Nail_clubbing

Acropachy

Skin disorder associated with Graves' disease

(also known as "isolated congenital nail clubbing") may be associated with HPGD. Periosteal reaction Graf, Gratton (2013). Imboden; Hellmann; Stone (eds

Acropachy

Pachydermoperiostosis

Rare genetic disorder that affects bones and skin

associated with mutations of HPGD gene. These patients showed typical PDP symptoms such as digital clubbing and periostosis. The HPGD gene is mapped on chromosome

Pachydermoperiostosis

Hematopoietic prostaglandin D synthase

Protein-coding gene in the species Homo sapiens

Glutathione-Dependent PGD Synthase, is a protein that in humans is encoded by the HPGDS gene. HPGDS is a bifunctional enzyme. One of its functions is to act as a Prostaglandin-D

Hematopoietic prostaglandin D synthase

Hematopoietic_prostaglandin_D_synthase

Unhook the Stars

1996 film by Nick Cassavetes

in Salt Lake City, Utah. The film was co-produced by the French company HPGD, a subsidiary of Hachette group created in association with actor Gérard

Unhook the Stars

Unhook_the_Stars

Short-chain dehydrogenase

Protein family

DHRS3; DHRS4; DHRS4L2; DHRS7; DHRS7B; DHRS8; DHRS9; DHRSX; FASN; FVT1; HADH2; HPGD; HSD11B1; HSD11B2; HSD17B1; HSD17B10; HSD17B12; HSD17B13; HSD17B2; HSD17B3;

Short-chain dehydrogenase

Short-chain_dehydrogenase

Cyclopentenone prostaglandins

Prostaglandin subset

L-PGDS) and a glutathione-dependent hematopoietic prostaglandin D synthase or HPGDS; the COX's also metabolizes dihomo-gamma-linolenic acid to PGH1 which is

Cyclopentenone prostaglandins

Cyclopentenone_prostaglandins

ML148

Pharmaceutical compound

selective inhibitors of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD)". Probe Reports from the NIH Molecular Libraries Program. Bethesda: National

ML148

Shuji Ogino

Japanese epidemiologist

in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD). Sci Transl Med 2014;6:233re2. Mehta, RS; Nishihara, R; Cao, Y; Song, M;

Shuji Ogino

Shuji_Ogino

List of human protein-coding genes 4

HPDL HGNC:28242; Q96IR7 7239 HPF1 HGNC:26051; Q9NWY4 7240 HPGD HGNC:5154; P15428 7241 HPGDS HGNC:17890; O60760 7242 HPN HGNC:5155; P05981 7243 HPR HGNC:5156;

List of human protein-coding genes 4

List_of_human_protein-coding_genes_4

List of OMIM disorder codes

Craniometaphyseal dysplasia; 123000; ANKH Cranioosteoarthropathy; 259100; HPGD Craniosynostosis, type 1; 123100; TWIST1 Craniosynostosis, type 2; 604757;

List of OMIM disorder codes

List_of_OMIM_disorder_codes

Prostaglandin-D synthase

Class of enzymes

two proteins that catalyze this reaction, encoded by the genes PTGDS and HPGDS. Using systematic notation, the chemical reaction is (5Z,13E)-(15S)-9alpha

Prostaglandin-D synthase

Prostaglandin-D_synthase

Glutathione S-transferase, C-terminal domain

Protein domain

GSTM1; GSTM2; GSTM3; GSTM4; GSTM5; GSTO1; GSTP1; GSTT1; GSTT2; GSTZ1; MARS; HPGDS; PTGDS2; PTGES2; VARS; Armstrong RN (1997). "Structure, Catalytic Mechanism

Glutathione S-transferase, C-terminal domain