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HOXB1

  • HOXB1
  • Protein-coding gene in the species Homo sapiens

    Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. This gene belongs to the homeobox family of genes. The homeobox genes

    HOXB1

    HOXB1

    HOXB1

  • Heritability of autism
  • Gill M (January 2004). "No association between allelic variants of HOXA1/HOXB1 and autism". American Journal of Medical Genetics. Part B, Neuropsychiatric

    Heritability of autism

    Heritability of autism

    Heritability_of_autism

  • Hox gene
  • Group of genes

    HOXA5, HOXA6, HOXA7, HOXA9, HOXA10, HOXA11, HOXA13 HOXB@ chromosome 17 HOXB1, HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, HOXB13 HOXC@ chromosome

    Hox gene

    Hox_gene

  • Chromosome 17
  • Human chromosome

    DDX52 FOX (forkhead box) proteins: FOXJ1, FOXK2, FOXN1 Homeobox B genes: HOXB1, HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, HOXB13 Integrin

    Chromosome 17

    Chromosome 17

    Chromosome_17

  • List of human transcription factors
  • ENSG00000078399 Homeodomain Known motif – High-throughput in vitro [382] DTTWAYGAY HOXB1 ENSG00000120094 Homeodomain Known motif – High-throughput in vitro [383]

    List of human transcription factors

    List_of_human_transcription_factors

  • Retinoic acid
  • Metabolite of vitamin A

    within flanking sequences of some of the most 3′ Hox genes (including HOXA1, HOXB1, HOXB4, HOXD4), suggesting a direct interaction between the genes and retinoic

    Retinoic acid

    Retinoic acid

    Retinoic_acid

  • Gastrulation
  • Embryologic stage in which germ layers form

    promotes hepatic fate. RA signaling also induce homeobox genes such as Hoxb1 and Hoxa5. In mice, if there is a lack in RA signaling the mouse will not

    Gastrulation

    Gastrulation

    Gastrulation

  • SOX2
  • Transcription factor gene of the SOX family

    Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex". The Journal of Biological Chemistry

    SOX2

    SOX2

    SOX2

  • PBX1
  • Protein found in humans

    generation and skeletal patterning. PBX1 has been shown to interact with: HOXB1, HOXB7, MEIS1, and Prep1. The Drosophila melangoster gene called extradenticle

    PBX1

    PBX1

    PBX1

  • Neuronal lineage marker
  • Endogenous tag expressed in different cells along neurogenesis and differentiated cells

    Frizzled-9; sFRP-2; GATA-2; SLAIN 1; GCNF/NR6A1; SOX1; GFAP; SOX2; Glut1; SOX9; HOXB1; SOX11; ID2; SOX21; Meteorin; SSEA-1; MSX1; TRAF-4; Musashi-1; Vimentin;

    Neuronal lineage marker

    Neuronal lineage marker

    Neuronal_lineage_marker

  • Homeobox
  • DNA pattern affecting anatomy development

    HOXA6, HOXA7, HOXA9, HOXA10, HOXA11, HOXA13 HOXB - HOXB@ chromosome 17 HOXB1, HOXB2, HOXB3, HOXB4, HOXB5, HOXB6, HOXB7, HOXB8, HOXB9, HOXB13 HOXC - HOXC@

    Homeobox

    Homeobox

    Homeobox

  • Christiana Ruhrberg
  • German-British cell biologist

    E.; Krumlauf, Robb (2003). "Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes"

    Christiana Ruhrberg

    Christiana Ruhrberg

    Christiana_Ruhrberg

  • Homeobox A1
  • Protein-coding gene in humans

    Rodier PM (December 2000). "Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders". Teratology. 62 (6):

    Homeobox A1

    Homeobox A1

    Homeobox_A1

  • Rhombomere
  • Transient structure in animal development

    Certain neuron groups relate to Hox gene expression. At the r4 level, Hoxb1 is suspected to bestow rhombomere 4 cell identity. Rhombomeres have also

    Rhombomere

    Rhombomere

  • HOXB3
  • Protein-coding gene in the species Homo sapiens

    Viganò A, Boncinelli E (1998). "Regulatory interactions between the human HOXB1, HOXB2, and HOXB3 proteins and the upstream sequence of the Otx2 gene in

    HOXB3

    HOXB3

    HOXB3

  • Andrew Lumsden (scientist)
  • British neuroscientist

    (1999). "Homeotic transformation of rhombomere identity following localised Hoxb1 misexpression". Science. 284 (5423): 2168–2171. doi:10.1126/science.284

    Andrew Lumsden (scientist)

    Andrew Lumsden (scientist)

    Andrew_Lumsden_(scientist)

  • POU2F1
  • Protein-coding gene in the species Homo sapiens

    OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT 1oct: CRYSTAL STRUCTURE OF THE OCT-1 POU DOMAIN BOUND

    POU2F1

    POU2F1

    POU2F1

  • List of human protein-coding genes 4
  • P31260 7202 HOXA11 HGNC:5101; P31270 7203 HOXA13 HGNC:5102; P31271 7204 HOXB1 HGNC:5111; P14653 7205 HOXB2 HGNC:5113; P14652 7206 HOXB3 HGNC:5114; P14651

    List of human protein-coding genes 4

    List_of_human_protein-coding_genes_4

  • HOXB2
  • Protein-coding gene in humans

    A, Boncinelli E (May 1998). "Regulatory interactions between the human HOXB1, HOXB2, and HOXB3 proteins and the upstream sequence of the Otx2 gene in

    HOXB2

    HOXB2

    HOXB2

  • Germline development
  • How an animal develops its sexual-reproduction cells

    thought to repress somatic gene expression, including the mesodermal marker Hoxb1. So, Blimp1, Tcfap2c and Prdm14 together are able to activate and repress

    Germline development

    Germline_development

  • SOX21
  • Protein-coding gene in the species Homo sapiens

    TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

    SOX21

    SOX21

    SOX21

  • SOX14
  • Protein-coding gene in the species Homo sapiens

    TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

    SOX14

    SOX14

    SOX14

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