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HLA B7

  • HLA-B7
  • Human leukocyte antigen serotype

    HLA-B7 (B7) is an HLA-B serotype. The serotype identifies the more common HLA-B*07 gene products. (For terminology help see: HLA-serotype tutorial) B7

    HLA-B7

    HLA-B7

    HLA-B7

  • B7
  • Topics referred to by the same term

    system HLA-B7, an HLA-B serotype Vitamin B7, another name for biotin A subclass of B-class stars Boron-7 (B-7 or 7B), an isotope of boron B7 the hexadecimal

    B7

    B7

  • Human leukocyte antigen
  • Genes on human chromosome 6

    The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation

    Human leukocyte antigen

    Human leukocyte antigen

    Human_leukocyte_antigen

  • HLA B7-DR15-DQ6
  • HLA B7-DR15-DQ6 is a multigene haplotype that covers a majority of the human major histocompatibility complex on chromosome 6. A multigene haplotype is

    HLA B7-DR15-DQ6

    HLA_B7-DR15-DQ6

  • HLA-Cw7
  • Part of the human genome

    the AH8.1 and HLA B7-DR15-DQ6 haplotypes. The class I region of these supertype is HLA A1-B8 haplotype, HLA A3-B7, HLA-A2-B7 and HLA A24-B7. Arce-Gomez

    HLA-Cw7

    HLA-Cw7

  • History and naming of human leukocyte antigens
  • Classification of leukocyte antigens

    reactive serotypes. For example, "HL-A2" became HLA-A2, "HL-A7" became HLA-B7 and "HL-A8" became HLA-B8. In this arrangement there were cells that were

    History and naming of human leukocyte antigens

    History_and_naming_of_human_leukocyte_antigens

  • Allovectin-7
  • Substance studied in cancer treatment

    melanoma. It is a plasmid/lipid complex containing the DNA sequences encoding HLA-B7 and β2 microglobulin - two components of major histocompatibility complex

    Allovectin-7

    Allovectin-7

  • HLA-A*02
  • Human leukocyte antigen serotype within the HLA-A serotype group

    of the HLA System revised the nomenclature for HLAs. Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is

    HLA-A*02

    HLA-A*02

    HLA-A*02

  • Sarcoidosis
  • Abnormal formation of clumps of inflammatory cells (granulomata)

    candidate gene is BTNL2; several HLA-DR risk alleles are also being investigated. In persistent sarcoidosis, the HLA haplotype HLA-B7-DR15 is either cooperating

    Sarcoidosis

    Sarcoidosis

    Sarcoidosis

  • HLA-A3
  • Human leukocyte antigen serotype

    patients. The HFE (Hemochromatosis) locus lies between A3 and B7 within the A3~DQ6 superhaplotype. HLA-A3 selects HIV evolution for a mutation Gag KK9 epitope

    HLA-A3

    HLA-A3

    HLA-A3

  • HLA-DQ1
  • Serotype that covers a broad range of HLA-DQ haplotypes

    HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1; later, it was

    HLA-DQ1

    HLA-DQ1

    HLA-DQ1

  • H-Y antigen
  • Sex-specific cell surface antigen in mammals

    from the Lysine-Specific Demethylase 5D protein (KDM5D gene) presented by HLA-B7. A third example is MEA1. It has been shown that male mice lacking in the

    H-Y antigen

    H-Y_antigen

  • HLA-B81
  • Human leukocyte antigen serotype

    B81 is poor when simultaneously tested with anti-B7 or B48 antibodies. (For terminology help see: HLA-serotype tutorial) The serotype recognition of B*8101

    HLA-B81

    HLA-B81

    HLA-B81

  • HLA-B67
  • Human leukocyte antigen serotype

    Pacific Rim (Taiwan, Japan, Korea, Coastal Siberia), and B7, B22, or B27. (For terminology help see: HLA-serotype tutorial) Marsh, S. G.; Albert, E. D.; Bodmer

    HLA-B67

    HLA-B67

  • HLA-A1
  • Human leukocyte antigen serotype

    HLA-A1 (A1) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody recognition of α1 subset

    HLA-A1

    HLA-A1

    HLA-A1

  • Jack L. Strominger
  • American biochemist

    of HLA-A2, HLA-A68, and HLA-B27. Ultimately, papain-solubilized fragments of the human class II MHC antigens HLA-DR1, HLA-DR2, HLA-DR3, HLA-DR4, HLA-DR7

    Jack L. Strominger

    Jack_L._Strominger

  • HLA A1-B8-DR3-DQ2
  • Human genotype

    the longest, HLA A3-Cw7-B7-DR15-DQ6 (A3::DQ6), had already undergone significant recombination and is nearly equal in frequency to HLA A2-Cw7::DQ6 bearing

    HLA A1-B8-DR3-DQ2

    HLA_A1-B8-DR3-DQ2

  • HLA-C
  • Protein-coding gene in the species Homo sapiens

    Native Americans) Cw7-B7 (Western Eurasia, South Africa) Cw7-B8 (Western Eurasia) Cw1-B46 (China, Indochina) Cw5-B44 (Western Eurasia) HLA-C has been shown

    HLA-C

    HLA-C

    HLA-C

  • HLA-B61
  • Serotype

    Ways JP, Lawlor DA, Wan AM, Parham P (1987). "A transposable epitope of HLA-B7, B40 molecules". Immunogenetics. 25 (5): 323–8. doi:10.1007/BF00404425.

    HLA-B61

    HLA-B61

  • HLA-B54
  • Human leukocyte antigen serotype

    ; Parham, P. (1992). "HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix". Journal of Immunology. 148 (4): 1155–1162. PMID 1737933

    HLA-B54

    HLA-B54

  • HLA-DR15
  • HLA-DR serotype

    HLA-DR15 (DR15) is a HLA-DR serotype that recognizes the DRB1*1501 to *1505 and *1507 gene products. DR15 is found at high levels from Ireland to Central

    HLA-DR15

    HLA-DR15

    HLA-DR15

  • HLA-B60
  • Human leukocyte antigen serotype

    Ways JP, Lawlor DA, Wan AM, Parham P (1987). "A transposable epitope of HLA-B7, B40 molecules". Immunogenetics. 25 (5): 323–8. doi:10.1007/BF00404425.

    HLA-B60

    HLA-B60

  • HLA-DQ6
  • Human leukocyte antigen serotype

    (DQA1*0102 : DQB1*0602) is commonly linked to DR15 and as such is part of the HLA B7-DR15-DQ6 haplotype. This haplotype is considered to be the longest multigene

    HLA-DQ6

    HLA-DQ6

    HLA-DQ6

  • Acute posterior multifocal placoid pigment epitheliopathy
  • Eye disease causing lesions in retina

    accompanies it. It is associated with an increased incidence of both HLA-B7 and HLA-DR2.[citation needed] The underlying etiology of APMPPE continues to

    Acute posterior multifocal placoid pigment epitheliopathy

    Acute posterior multifocal placoid pigment epitheliopathy

    Acute_posterior_multifocal_placoid_pigment_epitheliopathy

  • HLA-A
  • Protein-coding gene in the species Homo sapiens

    HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility

    HLA-A

    HLA-A

    HLA-A

  • HLA-A23
  • Human leukocyte antigen serotype

    HLA-A23 (A23) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α23 subset of

    HLA-A23

    HLA-A23

    HLA-A23

  • List of MeSH codes (D23)
  • 400.380 – HLA-B MeSH D23.050.301.500.400.380.383 – HLA-B7 MeSH D23.050.301.500.400.380.385 – HLA-B8 MeSH D23.050.301.500.400.380.387 – HLA-B27 MeSH D23

    List of MeSH codes (D23)

    List_of_MeSH_codes_(D23)

  • HLA-A32
  • Human leukocyte antigen serotype

    HLA-A32 (A32) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α32 subset of

    HLA-A32

    HLA-A32

    HLA-A32

  • HLA-B
  • Protein-coding gene in the species Homo sapiens

    critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system

    HLA-B

    HLA-B

    HLA-B

  • Artificial antigen-presenting cell
  • murine fibroblasts to express specific peptide-loaded HLA molecules with co-stimulatory signal B7.1, and cell adhesion molecules ICAM-1 and LFA-3. Many

    Artificial antigen-presenting cell

    Artificial_antigen-presenting_cell

  • Beta-2 microglobulin
  • Component of MHC class I molecules

    alloantigen). Nevertheless, the β2 microglobulin gene is outside of the MHC (HLA) locus, on a different chromosome. An additional function is association

    Beta-2 microglobulin

    Beta-2 microglobulin

    Beta-2_microglobulin

  • Immunoediting
  • example downregulation or loss of expression of classical MHC class I (HLA-A, HLA-B- HLA-C) which is essential for effective T cell-mediated immune response

    Immunoediting

    Immunoediting

  • Antigen-presenting cell
  • Cell that displays antigen bound by MHC proteins on its surface

    co-stimulatory molecules required for T cell activation, including CD40 and B7. The latter can interact with CD28 on the surface of a CD4+ T cell. The dendritic

    Antigen-presenting cell

    Antigen-presenting cell

    Antigen-presenting_cell

  • List of airline codes
  • HYPERION Malta HFM Hi Fly Malta MOONRAKER Malta A5 HOP Hop! AIR HOP France HLA HC Airlines HEAVYLIFT United Kingdom HWD HPM Investments FLITEWISE United

    List of airline codes

    List_of_airline_codes

  • Pre-eclampsia
  • Hypertension occurring during pregnancy

    not T-cells. NK cells use KIR receptors on their surface to recognize the HLA-C molecules on the surfaces of extravillous trophoblast (EVT) cells. In cases

    Pre-eclampsia

    Pre-eclampsia

    Pre-eclampsia

  • Cytotoxic T-lymphocyte associated protein 4
  • Mammalian protein found in humans

    identified in 1991 as a second receptor for the T cell costimulation ligand B7. In November 1995, the labs of Tak Wah Mak and Arlene Sharpe independently

    Cytotoxic T-lymphocyte associated protein 4

    Cytotoxic T-lymphocyte associated protein 4

    Cytotoxic_T-lymphocyte_associated_protein_4

  • Outline of immunology
  • Overview of and topical guide to immunology

    complex MHC class I HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G MHC class II HLA-DM α β HLA-DO α β HLA-DP α1 β1 HLA-DQ α1 α2 β1 β2 β3 HLA-DR α β1 β3 β4 β5 Early

    Outline of immunology

    Outline_of_immunology

  • Immunologic constant of rejection
  • Signature : CCL5, CD27, CD274 (PD-L1), CD276 (B7-H3), CD8A, CMKLR1, CXCL9, CXCR6, HLA-DQA1, HLA-DRB1, HLA-E, IDO1, LAG3, NKG7, PDCD1LG2 (PDL2), PSMB10

    Immunologic constant of rejection

    Immunologic_constant_of_rejection

  • NFKBIL1
  • Protein-coding gene in the species Homo sapiens

    MHC gene IKBL carries a structural polymorphism that is associated with HLA-A3,B7,DR15". Immunogenetics. 49 (7–8): 660–5. doi:10.1007/s002510050662. PMID 10369924

    NFKBIL1

    NFKBIL1

    NFKBIL1

  • BTNL2
  • Protein-coding gene in the species Homo sapiens

    truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15". Human Molecular Genetics. 15 (1): 155–161. doi:10.1093/hmg/ddi436

    BTNL2

    BTNL2

    BTNL2

  • NCR3
  • Mammalian protein found in Homo sapiens

    as transformed cell patterns. Ligation of NKp30 and intracellular protein HLA-B-associated transcript 3 (BAT3) released by tumour cells to extracellular

    NCR3

    NCR3

    NCR3

  • T cell
  • Type of white blood cell

    from the CD80 and CD86 proteins, which together constitute the B7 protein, (B7.1 and B7.2, respectively) on the APC. Other receptors are expressed upon

    T cell

    T cell

    T_cell

  • Cancer immunology
  • Study of the role of the immune system in cancer

    Tumor cells have non-classical MHC class I on their surface, for example HLA-G. HLA-G is inducer of Treg, MDSC, polarise macrophages into alternatively activated

    Cancer immunology

    Cancer immunology

    Cancer_immunology

  • Björn Dahlbäck
  • Swedish Doctor

    and Vascular Biology. 22 (4): 530–538. doi:10.1161/01.ATV.0000012665.51263.B7. PMID 11950687. S2CID 13215200. Blom, Anna M.; Villoutreix, Bruno O.; Dahlbäck

    Björn Dahlbäck

    Björn_Dahlbäck

  • NFX1
  • Protein-coding gene in the species Homo sapiens

    transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in

    NFX1

    NFX1

    NFX1

  • Cytotoxic T cell
  • T cell that kills infected, damaged or cancerous cells

    T-lymphocytes attack the new organ after detecting it as foreign, due to HLA variation between donor and recipient); in excessive cytokine production

    Cytotoxic T cell

    Cytotoxic T cell

    Cytotoxic_T_cell

  • Vaccine therapy
  • Type of medical treatment

    MC, Melioli G (December 2000). "Dendritic cells efficiently cross-prime HLA class I-restricted cytolytic T lymphocytes when pulsed with both apoptotic

    Vaccine therapy

    Vaccine_therapy

  • Tolerogenic dendritic cell
  • of immunomodulatory molecules such as PD-L1 and PD-L2, heme oxygenase 1, HLA-G, CD95L, TNF-related apoptosis inducing ligands, galectin-1 and DC-SIGN

    Tolerogenic dendritic cell

    Tolerogenic_dendritic_cell

  • Immunoreceptor tyrosine-based inhibitory motif
  • C, Wu T, Zhen Y, Xia XP, Zhao Y (December 2005). "BTLA, a new inhibitory B7 family receptor with a TNFR family ligand" (PDF). Cellular & Molecular Immunology

    Immunoreceptor tyrosine-based inhibitory motif

    Immunoreceptor_tyrosine-based_inhibitory_motif

  • XBP1
  • Protein-coding gene in the species Homo sapiens

    transcriptional element in the promoter of the human leukocyte antigen (HLA) DR alpha. The expression of this protein is required for the transcription

    XBP1

    XBP1

    XBP1

  • Cancer immunotherapy
  • Artificial stimulation of the immune system to treat cancer

    Finally, effectiveness of neoantigens may also be regulated by the specific HLA repertoire possessed by specific patient sub-groups. In the 1980s, Japan's

    Cancer immunotherapy

    Cancer immunotherapy

    Cancer_immunotherapy

  • Ha (Indic)
  • Letter "Ha" in Indic scripts

    हु [hʊ] = 1,000,000 (१० ०० ०००) हृ [hri] = 100,000,000 (१० ०० ०० ०००) हॢ [hlə] = ×1010 (१०१०) हे [he] = ×1012 (×१०१२) है [hɛː] = ×1014 (×१०१४) हो [hoː]

    Ha (Indic)

    Ha_(Indic)

  • List of human clusters of differentiation
  • functions by binding one of two possible costimulatory ligands, CD80 (B7.1) or CD86 (B7.2), thus eliciting a costimulatory effect on the T-cell CD29 AKA integrin

    List of human clusters of differentiation

    List_of_human_clusters_of_differentiation

  • T-box transcription factor T
  • Protein-coding gene in the species Homo sapiens

    potent ligands. Additionally, brachyury-specific peptides are presented on HLA receptors of cells in which it is expressed, representing a tumor specific

    T-box transcription factor T

    T-box transcription factor T

    T-box_transcription_factor_T

  • FOXP3
  • Immune response protein

    (April 2011). "Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation". Blood. 117 (14): 3921–3928. doi:10

    FOXP3

    FOXP3

    FOXP3

  • Index of oncology articles
  • Azoxymethane – AZQ – AZT B cell – B lymphocyte – B3 antigen – B43-PAP immunotoxin – B7-1 – Bacillus Calmette Guérin – Bacterial toxin – Barium enema – Barium solution

    Index of oncology articles

    Index_of_oncology_articles

  • Immune tolerance
  • State of unresponsiveness of the immune system

    tolerance. Placental trophoblast cells express a unique Human Leukocyte Antigen (HLA-G) that inhibits attack by maternal NK cells. These cells also express IDO

    Immune tolerance

    Immune_tolerance

  • Prostaglandin H2
  • Chemical compound

    Chemical Society. 106 (20): 6049–6060. doi:10.1021/ja00332a049. ISSN 0002-7863. Hla T, Neilson K (August 1992). "Human cyclooxygenase-2 cDNA". Proceedings of

    Prostaglandin H2

    Prostaglandin H2

    Prostaglandin_H2

  • Polyclonal B cell response
  • Immune response by adaptive immune system

    transplantation, and in humans is also known as the human leukocyte antigen (HLA). Here, intact implies that the undigested protein is recognized, and not

    Polyclonal B cell response

    Polyclonal B cell response

    Polyclonal_B_cell_response

  • RING1
  • Protein-coding gene in the species Homo sapiens

    CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL

    RING1

    RING1

    RING1

  • RFX1
  • Protein-coding gene in the species Homo sapiens

    PMC 358479. PMID 8289803. "Entrez Gene: RFX1 regulatory factor X, 1 (influences HLA class II expression)". Emery P, Durand B, Mach B, Reith W (March 1996). "RFX

    RFX1

    RFX1

    RFX1

  • CREBL1
  • Protein-coding gene in the species Homo sapiens

    Kozono H, et al. (1996). "A novel Creb family gene telomeric of HLA-DRA in the HLA complex". Genomics. 30 (2): 149–56. doi:10.1006/geno.1995.9891. PMID 8586413

    CREBL1

    CREBL1

    CREBL1

  • RFX3
  • Protein-coding gene in the species Homo sapiens

    PMC 358479. PMID 8289803. "Entrez Gene: RFX3 regulatory factor X, 3 (influences HLA class II expression)". Emery P, Durand B, Mach B, Reith W (1996). "RFX proteins

    RFX3

    RFX3

    RFX3

  • CUTL1
  • Protein-coding gene in the species Homo sapiens

    These physical interactions are reported in BioPlex 2.0 MAGEA10 EXT2 RAB30 HLA-DQA1 STX6 WDR83 SLC39A4 LAMP1 POTEB SLC39A12 This CASP is not the same as

    CUTL1

    CUTL1

    CUTL1

  • RFX5
  • Protein-coding gene in the species Homo sapiens

    PMID 9401005. S2CID 41660134. "Entrez Gene: RFX5 regulatory factor X, 5 (influences HLA class II expression)". Hake SB, Masternak K, Kammerbauer C, Janzen C, Reith

    RFX5

    RFX5

    RFX5

  • RFX4
  • Protein-coding gene in the species Homo sapiens

    M108638200. PMID 11682486. "Entrez Gene: RFX4 regulatory factor X, 4 (influences HLA class II expression)". Joung J, Ma S, Tay T, Geiger-Schuller KR, Kirchgatterer

    RFX4

    RFX4

    RFX4

  • RFX2
  • Protein-coding gene in the species Homo sapiens

    PMID 1505960. "Entrez Gene: RFX2 regulatory factor X, 2 (influences HLA class II expression)". Reith W, Ucla C, Barras E, et al. (1994). "RFX1, a

    RFX2

    RFX2

    RFX2

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