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GRIN2A

  • GRIN2A
  • Protein-coding gene in the species Homo sapiens

    [NMDA] subunit epsilon-1 is a protein that in humans is encoded by the GRIN2A gene. With 1464 amino acids, the canonical GluN2A subunit isoform is large

    GRIN2A

    GRIN2A

    GRIN2A

  • GRIN disorder
  • Medical disorder

    Subunits of NMDA receptor are encoded by GRIN genes: GRIN1 codes for GluN1; GRIN2A, GRIN2B, GRIN2C, and GRIN2D code for GluN2 A to D; GRIN3A and GRIN3B code

    GRIN disorder

    GRIN_disorder

  • Attention deficit hyperactivity disorder
  • Neurodevelopmental disorder

    and DBH. Other genes associated with ADHD include SERT, HTR1B, SNAP25, GRIN2A, ADRA2A, TPH2, and BDNF. A common variant of a gene called latrophilin 3

    Attention deficit hyperactivity disorder

    Attention_deficit_hyperactivity_disorder

  • Ligand-gated ion channel
  • Type of ion channel transmembrane protein

    GRINL1A GRINL1B GLUN1, NMDA-R1, NR1, GluRξ1 GluN2A GluN2B GluN2C GluN2D GRIN2A GRIN2B GRIN2C GRIN2D GLUN2A, NMDA-R2A, NR2A, GluRε1 GLUN2B, NMDA-R2B, NR2B

    Ligand-gated ion channel

    Ligand-gated ion channel

    Ligand-gated_ion_channel

  • NMDA receptor
  • Glutamate receptor and ion channel protein found in nerve cells

    may produce more than one splice variant. GluN1 – GRIN1 GluN2 GluN2A – GRIN2A GluN2B – GRIN2B GluN2C – GRIN2C GluN2D – GRIN2D GluN3 GluN3A – GRIN3A GluN3B

    NMDA receptor

    NMDA receptor

    NMDA_receptor

  • Ionotropic glutamate receptor
  • Ligand-gated ion channels

    GluK3/GRIK3; GluK4/GRIK4; GluK5/GRIK5; NMDA receptors: GluN1/GRIN1; GluN2A/GRIN2A; GluN2B/GRIN2B; GluN2C/GRIN2C; GluN2D/GRIN2D; GluN3A/GRIN3A; GluN3B/GRIN3B;

    Ionotropic glutamate receptor

    Ionotropic glutamate receptor

    Ionotropic_glutamate_receptor

  • Causes of schizophrenia
  • Field of study

    mutations in genes related to glutamatergic neurotransmission, such as GRIN2A, GRIA1, SRR, and GRM3. Recent research has suggested a link between gut

    Causes of schizophrenia

    Causes_of_schizophrenia

  • Lynette Sadleir
  • Canadian synchronized swimmer and paediatric neurologist

    Gemma L Carvill; Brigid M Regan; Simone C Yendle; et al. (11 August 2013). "GRIN2A mutations cause epilepsy-aphasia spectrum disorders". Nature Genetics. 45

    Lynette Sadleir

    Lynette Sadleir

    Lynette_Sadleir

  • List of human protein-coding genes 3
  • HGNC:4582; Q16099 6644 GRIK5 HGNC:4583; Q16478 6645 GRIN1 HGNC:4584; Q05586 6646 GRIN2A HGNC:4585; Q12879 6647 GRIN2B HGNC:4586; Q13224 6648 GRIN2C HGNC:4587; Q14957

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • Glutamate receptor
  • Neuron membrane protein

    3 GluK5 (KA-2) GRIK5 19q13.2 NMDA GluN1(NR1) GRIN1 9q34.3 GluN2A (NR2A) GRIN2A 16p13.2 GluN2B (NR2B) GRIN2B 12p12 GluN2C (NR2C) GRIN2C 17q24-q25 GluN2D

    Glutamate receptor

    Glutamate receptor

    Glutamate_receptor

  • GRIN2D
  • Protein-coding gene in the species Homo sapiens

    subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2D has been

    GRIN2D

    GRIN2D

    GRIN2D

  • Causes of mental disorders
  • Etiology of psychopathology

    and DBH. Other genes associated with ADHD include SERT, HTR1B, SNAP25, GRIN2A, ADRA2A, TPH2, and BDNF. A common variant of a gene called latrophilin 3

    Causes of mental disorders

    Causes of mental disorders

    Causes_of_mental_disorders

  • DLG4
  • Mammalian protein found in Homo sapiens

    DLG3 DLGAP1 DLGAP2 DYNLL1 DYNLL2 ERBB4 EXOC4 FYN FZD7 GRIK1 GRIK2 GRIK5 GRIN2A GRIN2B GRIN2C HER2/neu HGS KCNA2 KCNA4 KCNA5 KCNJ12 Kir2.1 LGI1 LRP1 LRP2

    DLG4

    DLG4

    DLG4

  • GRIN2C
  • Protein-coding gene in the species Homo sapiens

    subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2C has been

    GRIN2C

    GRIN2C

    GRIN2C

  • GRIN2B
  • Protein-coding gene in the species Homo sapiens

    (GRIN1) and two drawn from one or more of the four NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). The NR2 subunit

    GRIN2B

    GRIN2B

    GRIN2B

  • DLG3
  • Protein-coding gene in humans

    DLG3 has been shown to interact with: APC, CRIPT, DLG4, EXOC3, EXOC4, GRIN2A, GRIN2B, GRIN2C, KCNJ12 PTK2B, and SYNGAP1. GRCh38: Ensembl release 89:

    DLG3

    DLG3

    DLG3

  • Interleukin 16
  • Protein-coding gene in the species Homo sapiens

    receptor for mature IL-16. Interleukin 16 has been shown to interact with: GRIN2A, GRIN2D, KCNJ10, KCNJ15, Kir2.1, PPP1R12A, and PPP1R12B. GRCh38: Ensembl

    Interleukin 16

    Interleukin 16

    Interleukin_16

  • PTK2B
  • Protein-coding gene in humans

    BCAR1, Cbl gene, ASAP2, DLG3, DLG4, Ewing sarcoma breakpoint region 1, FYN, GRIN2A, Gelsolin, NPHP1, PITPNM1, PTPN11, PTPN6, Paxillin, RAS p21 protein activator

    PTK2B

    PTK2B

    PTK2B

  • FYN
  • Protein-coding gene in humans

    CHRNA7, CTNND1, CBL, CSF1R, DLG4, Dystroglycan, EPHA8, FYB, FASLG, GNB2L1, GRIN2A, ITK, Janus kinase 2, KHDRBS1, Lck, LKB1, Nephrin, PAG1, PIK3R2, PRKCQ,

    FYN

    FYN

    FYN

  • Index of biophysics articles
  • Index of articles on biophysics

    GPCR oligomer GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A GRIN3B GRINL1A GRINL1B G protein G protein-coupled

    Index of biophysics articles

    Index_of_biophysics_articles

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GRIN2A