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GI ALPHA-SUBUNIT

  • Gi alpha subunit
  • InterPro Family

    Gi protein alpha subunit is a family of heterotrimeric G protein alpha subunits. Gi proteins primarily inhibit the cAMP dependent pathway by inhibiting

    Gi alpha subunit

    Gi_alpha_subunit

  • Alpha subunit
  • Topics referred to by the same term

    Alpha subunits (α) refers to several protein subunits, e.g.: G proteins Gi alpha subunit Gs alpha subunit Gq alpha subunit The pore-forming loop of ion

    Alpha subunit

    Alpha_subunit

  • Gq alpha subunit
  • Family of heterotrimeric G protein alpha subunits

    Gq protein alpha subunit is a family of heterotrimeric G protein alpha subunits. This family is also commonly called the Gq/11 (Gq/G11) family or Gq/11/14/15

    Gq alpha subunit

    Gq_alpha_subunit

  • Gs alpha subunit
  • Mammalian protein found in Homo sapiens

    The Gs alpha subunit (Gαs, Gsα) is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase

    Gs alpha subunit

    Gs alpha subunit

    Gs_alpha_subunit

  • G12/G13 alpha subunits
  • InterPro Family

    protein-coupled receptor Heterotrimeric G protein Gs alpha subunit Gi alpha subunit Gq alpha subunit Rho family of GTPases Dhanasekaran N, Dermott JM (1996)

    G12/G13 alpha subunits

    G12/G13_alpha_subunits

  • GNAI1
  • Protein-coding gene in humans

    nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene. As one of the 3 Gi alpha subunits, this protein has an

    GNAI1

    GNAI1

    GNAI1

  • GI
  • Topics referred to by the same term

    code GI), a 1999–2010 airline based in Kyrgyzstan Galvanized iron, a kind of metal Gi alpha subunit, a part of some proteins Gastrointestinal tract (GI tract)

    GI

    GI

  • GNAI3
  • Protein-coding gene in humans

    nucleotide-binding protein G(k) subunit alpha is a protein that in humans is encoded by the GNAI3 gene. This protein is one of the 4 subunits in the Gi/o family of G-proteins

    GNAI3

    GNAI3

    GNAI3

  • G alpha subunit
  • Protein family

    G alpha subunits are one of the three types of subunit of guanine nucleotide binding proteins, which are membrane-associated, heterotrimeric G proteins

    G alpha subunit

    G alpha subunit

    G_alpha_subunit

  • Mu-opioid receptor
  • Class of opioid receptors found in humans

    It is an inhibitory G-protein coupled receptor that activates the Gi alpha subunit, inhibiting adenylate cyclase activity, lowering cAMP levels. The structure

    Mu-opioid receptor

    Mu-opioid receptor

    Mu-opioid_receptor

  • G protein
  • Type of proteins

    class of complexes is made up of alpha (Gα), beta (Gβ) and gamma (Gγ) subunits. In addition, the beta and gamma subunits can form a stable dimeric complex

    G protein

    G protein

    G_protein

  • Prostaglandin receptor
  • Cell surface receptor

    and activate, i.e. those containing the Gs alpha subunit, Gi alpha subunit, Gq alpha subunit and/or G12 subunit; and f) signaling pathways which they regulate

    Prostaglandin receptor

    Prostaglandin_receptor

  • Somatostatin receptor
  • Cell surface protein binding somatostatin and triggering intracellular changes

    seven transmembrane receptors, and all are coupled to inhibitory (Gi alpha subunit family) G-proteins. One of the core functions of somatostatin is its

    Somatostatin receptor

    Somatostatin receptor

    Somatostatin_receptor

  • Metabotropic glutamate receptor 2
  • Mammalian protein found in humans

    mGluR2 is a G protein-coupled receptor (GPCR) that couples with the Gi alpha subunit. The receptor functions as an autoreceptor for glutamate, that upon

    Metabotropic glutamate receptor 2

    Metabotropic glutamate receptor 2

    Metabotropic_glutamate_receptor_2

  • Luteinizing hormone beta polypeptide
  • Protein-coding gene in the species Homo sapiens

    Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin

    Luteinizing hormone beta polypeptide

    Luteinizing hormone beta polypeptide

    Luteinizing_hormone_beta_polypeptide

  • G protein-gated ion channel
  • Furthermore, studies have shown that G proteins, specifically the Gi alpha subunit, directly activate GIRKs which were found to participate in propagation

    G protein-gated ion channel

    G protein-gated ion channel

    G_protein-gated_ion_channel

  • Prostaglandin DP2 receptor
  • Protein-coding gene in the species Homo sapiens

    triggers Gi alpha subunit-linked heterotrimeric G proteins to dissociate into their component a) Gi alpha subunits (also termed Giα subunits) inhibit

    Prostaglandin DP2 receptor

    Prostaglandin DP2 receptor

    Prostaglandin_DP2_receptor

  • Heterotrimeric G protein
  • Class of enzymes

    the G-protein by exchanging the GDP on the alpha subunit to GTP. The binding of GTP to the alpha subunit results in a structural change and its dissociation

    Heterotrimeric G protein

    Heterotrimeric G protein

    Heterotrimeric_G_protein

  • 5-Oxo-eicosatetraenoic acid
  • Chemical compound

    site which reversibly bound 5-oxo-ETE and had the attributes of a Gi alpha subunit-linked G protein-coupled receptor based on the ability of 5-oxo-ETE

    5-Oxo-eicosatetraenoic acid

    5-Oxo-eicosatetraenoic acid

    5-Oxo-eicosatetraenoic_acid

  • Alpha-2 adrenergic receptor
  • Protein family

    The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists

    Alpha-2 adrenergic receptor

    Alpha-2 adrenergic receptor

    Alpha-2_adrenergic_receptor

  • Cyclopentenone prostaglandins
  • Prostaglandin subset

    are G protein-coupled receptors, with the DP2 receptor coupled to Gi alpha subunit-dependent depression of cellular cAMP levels and causing the potentiation

    Cyclopentenone prostaglandins

    Cyclopentenone_prostaglandins

  • Regulator of G protein signaling
  • Protein family

    "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits". Cell. 86 (3): 445–52. doi:10.1016/S0092-8674(00)80117-8

    Regulator of G protein signaling

    Regulator of G protein signaling

    Regulator_of_G_protein_signaling

  • Prostacyclin receptor
  • Mammalian protein found in Homo sapiens

    activated T-cells; and EGF cellular receptors; and c) Gi alpha subunit-Giβγ) complexes which releases Gi that then simulates phospholipase C to cleave phosphatidylinositol

    Prostacyclin receptor

    Prostacyclin receptor

    Prostacyclin_receptor

  • CACNA1C
  • Protein-coding gene in humans

    calcium channel subunit alpha-1C (also known as Cav1.2) is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is a subunit of L-type voltage-dependent

    CACNA1C

    CACNA1C

    CACNA1C

  • 5-Hydroxyeicosatetraenoic acid
  • Chemical compound

    receptor). OXER1 couples to the G protein complex composed of the Gi alpha subunit (Gαi) and G beta-gamma complex (Gβγ); when bound to a 5-(S)-HETE family

    5-Hydroxyeicosatetraenoic acid

    5-Hydroxyeicosatetraenoic acid

    5-Hydroxyeicosatetraenoic_acid

  • T-complex 1
  • Protein-coding gene in the species Homo sapiens

    T-complex protein 1 or T-complex protein 1 subunit alpha, abbreviated TCP1 or TCP-1, is a protein that in humans is encoded by the TCP1 gene. This protein

    T-complex 1

    T-complex 1

    T-complex_1

  • PPP2R1A
  • Enzyme

    Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform is an enzyme that in humans is encoded by the PPP2R1A gene. In the plant

    PPP2R1A

    PPP2R1A

    PPP2R1A

  • GPR17
  • Protein-coding gene in the species Homo sapiens

    that acts primarily through G proteins linked to the Gi alpha subunit but also to Gq alpha subunit. Matching these structural relationships, GPR17 has

    GPR17

    GPR17

    GPR17

  • Cav1.1
  • Mammalian protein found in humans

    Cav1.1 also known as the calcium channel, voltage-dependent, L type, alpha 1S subunit, (CACNA1S), is a protein which in humans is encoded by the CACNA1S

    Cav1.1

    Cav1.1

    Cav1.1

  • 12-Hydroxyheptadecatrienoic acid
  • Chemical compound

    ligand-bound, activate cells by releasing the Gq alpha subunit and pertussis toxin-sensitive Gi alpha subunit from heterotrimeric G proteins. BLT1 receptor

    12-Hydroxyheptadecatrienoic acid

    12-Hydroxyheptadecatrienoic acid

    12-Hydroxyheptadecatrienoic_acid

  • Alpha blocker
  • Class of pharmacological agents

    Alpha blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic

    Alpha blocker

    Alpha blocker

    Alpha_blocker

  • GNAT1
  • Protein-coding gene in the species Homo sapiens

    nucleotide-binding protein G(t) subunit alpha-1 is a protein that in humans is encoded by the GNAT1 gene. Transducin is a 3-subunit guanine nucleotide-binding

    GNAT1

    GNAT1

    GNAT1

  • PPP2CA
  • Protein-coding gene in humans

    catalytic subunit alpha isoform is an enzyme that (in humans) is encoded by the PPP2CA gene. This gene encodes the phosphatase 2A catalytic subunit. Protein

    PPP2CA

    PPP2CA

    PPP2CA

  • GNAI2
  • Protein-coding gene in humans

    protein G(i), alpha-2 subunit is a protein that in humans is encoded by the GNAI2 gene. This protein is one of the 4 subunits in the Gi/o family of G-proteins

    GNAI2

    GNAI2

    GNAI2

  • GTPase
  • Class of enzymes

    composed of three distinct protein subunits named alpha (α), beta (β) and gamma (γ) subunits. The alpha subunits contain the GTP binding/GTPase domain

    GTPase

    GTPase

  • Prostaglandin D2 receptor
  • Mammalian protein found in Homo sapiens

    In contrast, the binding of PDG2 to PTGDR2 instead activates the Gi alpha subunit, decreasing cAMP levels and increasing intracellular calcium ion levels

    Prostaglandin D2 receptor

    Prostaglandin D2 receptor

    Prostaglandin_D2_receptor

  • Alpha-2A adrenergic receptor
  • Protein-coding gene in the species Homo sapiens

    relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these

    Alpha-2A adrenergic receptor

    Alpha-2A adrenergic receptor

    Alpha-2A_adrenergic_receptor

  • Prostaglandin EP3 receptor
  • Protein-coding gene in the species Homo sapiens

    depending upon the particular EP3 isoform: EP3α and EP3β isoforms activate Gi alpha subunit (i.e. Gαi)-G beta-gamma complexes (i.e. Gαi)-Gβγ) complexes) as well

    Prostaglandin EP3 receptor

    Prostaglandin EP3 receptor

    Prostaglandin_EP3_receptor

  • GNB4
  • Protein-coding gene in the species Homo sapiens

    of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important

    GNB4

    GNB4

    GNB4

  • Adenosine deaminase z-alpha domain
  • Protein domain

    deaminase z-alpha domain refers to an evolutionary conserved protein domain. This family consists of the N-terminus and thus the z-alpha domain of double-stranded

    Adenosine deaminase z-alpha domain

    Adenosine deaminase z-alpha domain

    Adenosine_deaminase_z-alpha_domain

  • Platelet-derived growth factor receptor A
  • Human protein-coding gene

    1990). "Platelet-derived growth factor receptor: current views of the two-subunit model". The Journal of Investigative Dermatology. 94 (6 Suppl): 53S–57S

    Platelet-derived growth factor receptor A

    Platelet-derived growth factor receptor A

    Platelet-derived_growth_factor_receptor_A

  • CAMP-dependent pathway
  • Signal cascade used for cell to cell communication

    an attached intracellular heterotrimeric G protein complex. The Gs alpha subunit of the stimulated G protein complex exchanges GDP for GTP and is released

    CAMP-dependent pathway

    CAMP-dependent_pathway

  • Saclofen
  • GABAB receptor antagonist

    dissociated beta gamma subunit of the g-protein with the intracellular loop between the 1st and 2nd domain of the VGCC's alpha-subunit; postsynaptically,

    Saclofen

    Saclofen

    Saclofen

  • GNAO1
  • Protein-coding gene in the species Homo sapiens

    nucleotide-binding protein G(o) subunit alpha is a protein that in humans is encoded by the GNAO1 gene. This protein is part of the Gi/o family of G-proteins,

    GNAO1

    GNAO1

    GNAO1

  • Integrin beta 6
  • Protein-coding gene in the species Homo sapiens

    is a protein that in humans is encoded by the ITGB6 gene. It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins which

    Integrin beta 6

    Integrin beta 6

    Integrin_beta_6

  • Luteinizing hormone
  • Gonadotropin secreted by the adenohypophysis

    glycoprotein. Each monomeric unit is a glycoprotein molecule; one alpha and one beta subunit make the full, functional protein. Its structure is similar to

    Luteinizing hormone

    Luteinizing hormone

    Luteinizing_hormone

  • Receptor (biochemistry)
  • Protein molecule receiving signals for a cell

    made up of 3 subunits: α (alpha), β (beta), and γ (gamma). In the inactive state, the three subunits associate together and the α-subunit binds GDP. G

    Receptor (biochemistry)

    Receptor (biochemistry)

    Receptor_(biochemistry)

  • PPP2R5A
  • Enzyme found in humans

    Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform is an enzyme that in humans is encoded by the PPP2R5A gene. The product

    PPP2R5A

    PPP2R5A

    PPP2R5A

  • Cav1.3
  • Protein found in humans

    Calcium channel, voltage-dependent, L type, alpha 1D subunit (also known as Cav1.3) is a protein that in humans is encoded by the CACNA1D gene. Cav1.3

    Cav1.3

    Cav1.3

    Cav1.3

  • GoLoco motif
  • Protein structural motif

    subunit G-alpha and a G-beta/G-gamma dimer. The inactive form contains the alpha subunit bound to GDP and complexes with the beta and gamma subunit.

    GoLoco motif

    GoLoco motif

    GoLoco_motif

  • GNB1
  • Protein-coding gene in the species Homo sapiens

    of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important

    GNB1

    GNB1

    GNB1

  • Sodium–potassium pump
  • Ion channel enzyme pump found in the membrane of all animal cells

    as Na+/K+-ATPase beta subunit. Several studies have detailed the evolution of cardiotonic steroid resistance of the alpha-subunit gene family of Na/K-ATPase

    Sodium–potassium pump

    Sodium–potassium pump

    Sodium–potassium_pump

  • Muscarinic acetylcholine receptor
  • Acetylcholine receptors named for their selective binding of muscarine

    bioinformatic techniques. G proteins contain an alpha-subunit that is critical to the functioning of receptors. These subunits can take a number of forms. There are

    Muscarinic acetylcholine receptor

    Muscarinic acetylcholine receptor

    Muscarinic_acetylcholine_receptor

  • Alpha-1B adrenergic receptor
  • Protein-coding gene in the species Homo sapiens

    PMID 2154750. Schwinn DA, Johnston GI, Page SO, et al. (1995). "Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence

    Alpha-1B adrenergic receptor

    Alpha-1B adrenergic receptor

    Alpha-1B_adrenergic_receptor

  • GNAZ
  • Protein-coding gene in the species Homo sapiens

    (G protein), alpha z polypeptide". Fan X, Brass LF, Poncz M, Spitz F, Maire P, Manning DR (October 2000). "The alpha subunits of Gz and Gi interact with

    GNAZ

    GNAZ

    GNAZ

  • PPP2R2A
  • Enzyme found in humans

    Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform is an enzyme regulator that in humans is encoded by the PPP2R2A gene

    PPP2R2A

    PPP2R2A

    PPP2R2A

  • Leukotriene B4 receptor 2
  • Protein-coding gene in humans

    proteins that contain either the Gi alpha subunit and are therefore inhibited by pertussis toxin or the Gq alpha subunit and therefore not inhibited by

    Leukotriene B4 receptor 2

    Leukotriene B4 receptor 2

    Leukotriene_B4_receptor_2

  • GNB2
  • Protein-coding gene in the species Homo sapiens

    of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important

    GNB2

    GNB2

    GNB2

  • Adrenergic neuron blockers
  • Class of drugs

    receptor is a G-protein-coupled receptor with the Gs alpha subunit as its main signaling protein. The subunit dissociates from the receptor when activated, subsequently

    Adrenergic neuron blockers

    Adrenergic_neuron_blockers

  • Alfred G. Gilman
  • American pharmacologist (1941–2015)

    (1996). "GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits". Cell. 86 (3): 445–452. doi:10.1016/S0092-8674(00)80117-8

    Alfred G. Gilman

    Alfred G. Gilman

    Alfred_G._Gilman

  • Monomorphic epitheliotropic intestinal T cell lymphoma
  • Medical condition

    proliferation. Mutations in the GNA12 gene. This gene encodes Gα12, a G alpha subunit that is required for stimuli to regulate cell function through Gα12-coupled

    Monomorphic epitheliotropic intestinal T cell lymphoma

    Monomorphic_epitheliotropic_intestinal_T_cell_lymphoma

  • IGBP1
  • Protein-coding gene in the species Homo sapiens

    and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2"

    IGBP1

    IGBP1

    IGBP1

  • EIF2B1
  • Protein-coding gene in humans

    Translation initiation factor eIF-2B subunit alpha is a protein that in humans is encoded by the EIF2B1 gene. EIF2B1 has been shown to interact with EIF2B5

    EIF2B1

    EIF2B1

    EIF2B1

  • Protein kinase A
  • Family of enzymes

    heterotrimeric G protein complex by protein domain dynamics. The Gs alpha subunit of the stimulated G protein complex exchanges GDP for GTP in a reaction

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • Adenylyl cyclase
  • Enzyme with key regulatory roles in most cells

    II, IV and IX are stimulated by alpha subunit of the G protein. Isoforms I, V and VI are most clearly inhibited by Gi, while other isoforms show less

    Adenylyl cyclase

    Adenylyl cyclase

    Adenylyl_cyclase

  • Acetylcholine receptor
  • Integral membrane protein

    needed] Binding of acetylcholine to the N termini of each of the two alpha subunits results in the 15° rotation of all M2 helices. The cytoplasm side of

    Acetylcholine receptor

    Acetylcholine receptor

    Acetylcholine_receptor

  • PRKAA2
  • Protein-coding gene in the species Homo sapiens

    catalytic subunit alpha-2 is an enzyme that in humans is encoded by the PRKAA2 gene. The protein encoded by this gene is a catalytic subunit of the AMP-activated

    PRKAA2

    PRKAA2

    PRKAA2

  • Muscarinic acetylcholine receptor M2
  • Receptor protein found in humans

    coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits". Biochemistry. 36 (6): 1487–1495. doi:10.1021/bi962554d. PMID 9063897

    Muscarinic acetylcholine receptor M2

    Muscarinic acetylcholine receptor M2

    Muscarinic_acetylcholine_receptor_M2

  • Pertussis toxin
  • Group of toxins

    cell membrane, thus interfering with intracellular communication. The Gi subunits remain locked in their GDP-bound, inactive state, thus unable to inhibit

    Pertussis toxin

    Pertussis toxin

    Pertussis_toxin

  • G protein-coupled receptor
  • Class of cell surface receptors coupled to G-protein-associated intracellular signaling

    protein for a GTP. The G protein's α subunit, together with the bound GTP, can then dissociate from the β and γ subunits to further affect intracellular signaling

    G protein-coupled receptor

    G protein-coupled receptor

    G_protein-coupled_receptor

  • PIK3CB
  • Protein-coding gene in the species Homo sapiens

    Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform is an enzyme that in humans is encoded by the PIK3CB gene. Phosphoinositide

    PIK3CB

    PIK3CB

    PIK3CB

  • PPP2R5D
  • Protein-coding gene in humans

    Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform is an enzyme that in humans is encoded by the PPP2R5D gene. Mutations

    PPP2R5D

    PPP2R5D

    PPP2R5D

  • Second messenger system
  • System of signaling molecules within a cell

    diphosphate) molecule on its alpha subunit for a GTP (guanosine triphosphate) molecule. Once this exchange takes place, the alpha subunit of the G-protein transducer

    Second messenger system

    Second_messenger_system

  • CCT6A
  • Protein-coding gene in humans

    PMID 8034610. "Entrez Gene: CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)". Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras

    CCT6A

    CCT6A

    CCT6A

  • RGS19
  • Protein-coding gene in the species Homo sapiens

    "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits". Cell. 86 (3): 445–452. doi:10.1016/S0092-8674(00)80117-8

    RGS19

    RGS19

    RGS19

  • RGS14
  • Protein-coding gene in the species Homo sapiens

    conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers

    RGS14

    RGS14

    RGS14

  • GNGT1
  • Protein-coding gene in the species Homo sapiens

    rod cells, and GNGT2 only occurs in cone cells, with a different alpha (Gα) subunit. GRCh38: Ensembl release 89: ENSG00000127928 – Ensembl, May 2017 GRCm38:

    GNGT1

    GNGT1

    GNGT1

  • AsKC11
  • Toxin found in the venom of the sea anemone

    cells and in the brain. This peptidic activation is direct, the Gi protein alpha subunit is not involved. Additionally, AsKC11 has the ability to activate

    AsKC11

    AsKC11

  • STAT2
  • Protein-coding gene in Homo sapiens

    (March 2002). "Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling". The Journal of Biological Chemistry

    STAT2

    STAT2

    STAT2

  • Adrenergic blocking agent
  • Class of drugs

    suppressed. The alpha-2 blocker acts on alpha-2 receptors. The alpha-2 receptor is a G-protein coupled receptor as well, which exert its action by Gi function

    Adrenergic blocking agent

    Adrenergic_blocking_agent

  • RGS20
  • Protein-coding gene in the species Homo sapiens

    proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through

    RGS20

    RGS20

    RGS20

  • Protein biosynthesis
  • Assembly of proteins inside biological cells

    quaternary structure and is composed of four polypeptide subunits – two A subunits and two B subunits. Patients with sickle cell anemia have a missense or

    Protein biosynthesis

    Protein biosynthesis

    Protein_biosynthesis

  • PPP4C
  • Protein-coding gene in humans

    "Entrez Gene: PPP4C protein phosphatase 4 (formerly X), catalytic subunit". Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC

    PPP4C

    PPP4C

    PPP4C

  • GNG2
  • Protein-coding gene in the species Homo sapiens

    coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits". Biochemistry. 36 (6): 1487–95. doi:10.1021/bi962554d. PMID 9063897

    GNG2

    GNG2

    GNG2

  • Endocrine system
  • Hormone-producing glands of a body

    superior thyroid artery. Parathyroid hormone acts on bone, the kidneys, and the GI tract to increase calcium reabsorption and phosphate excretion. In addition

    Endocrine system

    Endocrine system

    Endocrine_system

  • PCK1
  • Protein-coding gene in the species Homo sapiens

    carboxykinase-1 (PCK1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) map to human chromosome 20, extending the known region of

    PCK1

    PCK1

    PCK1

  • RGS4
  • Protein-coding gene in the species Homo sapiens

    for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes

    RGS4

    RGS4

    RGS4

  • AMP-activated protein kinase
  • Class of enzymes

    and γ subunits. Each of these three subunits takes on a specific role in both the stability and activity of AMPK. Specifically, the γ subunit includes

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • Amphetamine
  • Central nervous system stimulant

    synapses. Upon activation by amphetamine, TAAR1 can couple to the Gs alpha subunit and increase intracellular cAMPTooltip cyclic adenosine monophosphate

    Amphetamine

    Amphetamine

    Amphetamine

  • Prenylation
  • Addition of hydrophobic moieties to proteins or other biomolecules

    Sprang, SR (15 December 1995). "The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2". Cell. 83 (6): 1047–58. doi:10.1016/0092-8674(95)90220-1

    Prenylation

    Prenylation

    Prenylation

  • Spectrin
  • Cytoskeletal protein

    PMID 35954302. Huh, Gi-Yeong; Glantz, Susan B.; Je, Soojung; Morrow, Jon S.; Kim, Jung H. (December 2001). "Calpain proteolysis of alpha-II-spectrin in the

    Spectrin

    Spectrin

    Spectrin

  • Glucagon receptor
  • Protein-coding gene in the species Homo sapiens

    "Glucagon induces disaggregation of polymer-like structures of the alpha subunit of the stimulatory G protein in liver membranes". Proceedings of the

    Glucagon receptor

    Glucagon receptor

    Glucagon_receptor

  • Ricin
  • Type of lectin

    chaperones Hsc70 and Hsp90 and their co-chaperones, as well as by one subunit (RPT5) of the proteasome itself, that results in its folding to a catalytic

    Ricin

    Ricin

    Ricin

  • Clonidine
  • Alpha-adrenergic agonist

    Gi/Go-coupled G protein-coupled receptors that signal through heterotrimeric G proteins made up of a Gαi/o subunit protein and a paired Gβγ subunit complex

    Clonidine

    Clonidine

    Clonidine

  • Pyruvate decarboxylase
  • Class of enzymes

    dimer. The enzyme contains a beta-alpha-beta structure, yielding parallel beta-sheets. It contains 563 residue subunits in each dimer; the enzyme has strong

    Pyruvate decarboxylase

    Pyruvate decarboxylase

    Pyruvate_decarboxylase

  • SCN5A
  • Protein-coding gene in the species Homo sapiens

    protein type 5 subunit alpha, also known as NaV1.5 is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. NaV1.5 is

    SCN5A

    SCN5A

    SCN5A

  • Amino acid
  • Organic compounds containing amine and carboxylic groups

    classified according to the locations of the core structural functional groups (alpha- (α-), beta- (β-), gamma- (γ-) amino acids, etc.); other categories relate

    Amino acid

    Amino acid

    Amino_acid

  • RGS10
  • Protein-coding gene in the species Homo sapiens

    for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes

    RGS10

    RGS10

    RGS10

  • Conotoxin
  • Group of neurotoxins

    present. Alpha conotoxins have two types of cysteine arrangements, and are competitive nicotinic acetylcholine receptor antagonists. Alpha-GI is a peptide

    Conotoxin

    Conotoxin

    Conotoxin

  • List of MeSH codes (D12.644)
  • alpha subunits, gi-go MeSH D12.644.360.375.100.200.500 – gtp-binding protein alpha subunit, gi2 MeSH D12.644.360.375.100.300 – gtp-binding protein alpha subunits

    List of MeSH codes (D12.644)

    List_of_MeSH_codes_(D12.644)

AI & ChatGPT searchs for online references containing GI ALPHA-SUBUNIT

GI ALPHA-SUBUNIT

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  • Alpha
  • Girl/Female

    Greek American

    Alpha

    Firstbom.' The first letter of the Greek alphabet.

    Alpha

  • Alphu
  • Girl/Female

    Indian

    Alphu

    Loving

    Alphu

  • Alpha
  • Boy/Male

    Hindu

    Alpha

    First letter of the greek alphabet

    Alpha

  • Hyde
  • Surname or Lastname

    English

    Hyde

    English : topographic name for someone living on (and farming) a hide of land, Old English hī(gi)d. This was a variable measure of land, differing from place to place and time to time, and seems from the etymology to have been originally fixed as the amount necessary to support one (extended) family (Old English hīgan, hīwan ‘household’). In some cases the surname is habitational, from any of the many minor places named with this word, as for example Hyde in Greater Manchester, Bedfordshire, and Hampshire.English : variant of Ide, with inorganic initial H-. Compare Herrick.Jewish (American) : Americanized spelling of Haid.

    Hyde

  • CHEROKEE
  • Male

    English

    CHEROKEE

    Unisex name derived from the English pronunciation of Tsa-la-gi, a name that the Native American Cherokee people used to refer to themselves, CHEROKEE means "principal people."

    CHEROKEE

  • Drew
  • Surname or Lastname

    English

    Drew

    English : from a short form of Andrew.English (Norman) : from the Germanic personal name Drogo, which is of uncertain origin; it is possibly akin to Old Saxon (gi)drog ‘ghost’, ‘phantom’, or with a stem meaning ‘to bear’, ‘to carry’ (Old High German tragan). Whatever its origin, the name was borne by one of the sons of Charlemagne, and was subsequently popular throughout France in the forms Dreus, Drues (oblique case Dreu, Dr(i)u), whence it was introduced to England by the Normans. Drogo de Monte Acuto (as his name appears in its Latinized form) was a companion of William the Conqueror and founder of the Montagu family, among whom the personal name Drogo was revived in the 19th century.English (of Norman origin) : nickname from Middle English dreue, dru, Old French dru, ‘favorite’, ‘lover’ (originally an adjective, apparently from a Gaulish word meaning ‘strong’, ‘vigorous’, ‘lively’, but influenced by the sense of the Old High German element trūt, drūt ‘dear’, ‘beloved’).English (of Norman origin) : habitational name from any of various places in France called Dreux, from the Gaulish tribal name Durocasses.English (of Norman origin) : habitational name, with the preposition de, from any of the numerous places in France named from Old French rieux ‘streams’.Irish : when not an adoption of the English surname, a reduced Anglicized form of Gaelic Mac an Druaidh or Ó Druaidh or Ó Draoi ‘son’ and ‘descendant of the druid’, from draoi ‘druid’, genitive druadh or draoi.

    Drew

  • Altha
  • Girl/Female

    American, British, English, Greek

    Altha

    Healer; With Healing Power

    Altha

  • Napp
  • Surname or Lastname

    English

    Napp

    English : metonymic occupational name for a producer or seller of table linen, from Old French nappe ‘table cloth’.English : either a variant spelling of Knapp or a reduced variant of Scottish McNabb.Altered spelling of German Knapp.German : metonymic occupational name for a bowl and cup maker, from Middle Low German nap ‘bowl’, ‘mug’, or alternatively, from an old personal name formed with an element cognate with Old High German (gi-)nāda ‘grace’, ‘benevolence’.

    Napp

  • ALPHA
  • Male

    African

    ALPHA

    (ox); the first letter of the Greek alphabet.

    ALPHA

  • Aliha
  • Girl/Female

    Arabic

    Aliha

    Respectable

    Aliha

  • Altha
  • Girl/Female

    English American

    Altha

    Healer.

    Altha

  • Alpa
  • Girl/Female

    Gujarati, Hindu, Indian, Jain, Kannada, Malayalam, Marathi, Oriya, Sanskrit, Tamil, Telugu

    Alpa

    Little; Collection of Many Small Things

    Alpa

  • Alpa
  • Girl/Female

    Indian

    Alpa

    Little

    Alpa

  • Alpa | அல்பா
  • Girl/Female

    Tamil

    Alpa | அல்பா

    Little

    Alpa | அல்பா

  • Lothrop
  • Surname or Lastname

    English

    Lothrop

    English : habitational name from Lowthorpe in East Yorkshire, named with the Old Norse personal name Logi or Lági + þorp ‘outlying farmstead’In 1634 the name was brought to North America by the Rev. John Lathrop (b. 1584 in Etton, Yorkshire, England), a Puritan preacher fleeing religious persecution. He arrived at Plymouth Colony and lived in Scituate, MA until 1639, then moved to Barnstable MA, where his Bible can still be seen.

    Lothrop

  • Gi
  • Girl/Female

    Australian

    Gi

    Flower

    Gi

  • Alpha
  • Boy/Male

    African, Australian, Chinese, French, Latin, Swedish

    Alpha

    First Letter of the Greek Alphabet; Leader

    Alpha

  • Lye
  • Surname or Lastname

    English

    Lye

    English : topographic name for someone who lived near a meadow, pasture, or patch of arable land, Middle English l(e)ye (late Old English lēage, dative of lēah ‘wood’, ‘glade’); or a habitational name from Lye in Herefordshire (with the same etymology).French : habitational name from Lye in Indre.French (Lyé) : habitational name from places called Lié in Deux-Sèvres and Vendée.Norwegian : habitational name from a farmstead in Rogaland named Lye, Old Norse Lýgi meaning ‘alliance’, ‘covenant’, used to denote a place sanctified by such an agreement, such as a court or council meeting place.

    Lye

  • Alpha | அல்பா 
  • Boy/Male

    Tamil

    Alpha | அல்பா 

    First letter of the greek alphabet

    Alpha | அல்பா 

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Online names & meanings

  • Arni
  • Boy/Male

    Danish, German, Hindu, Indian, Marathi

    Arni

    Eagle; Eagle Power

  • Baruch
  • Biblical

    Baruch

    who is blessed

  • Chabeela
  • Boy/Male

    Indian, Punjabi, Sikh

    Chabeela

    Youthful; Beauteous

  • Wade
  • Boy/Male

    American, Anglo, Australian, British, Chinese, Christian, English, French, Scandinavian

    Wade

    To Go; Ford; Moving; From the River Crossing; River Ford

  • Farrah
  • Girl/Female

    American, Arabic, Australian, British, Chinese, Christian, English, French, German, Irish, Latin, Muslim

    Farrah

    Beautiful; Joyful; Lovely; Pleasant; Good-looking; Fair; Traveller

  • Abhisumant
  • Boy/Male

    Hindu, Indian, Traditional

    Abhisumant

    Radiant; Another Name of Sun

  • Paraminder
  • Girl/Female

    Indian, Punjabi, Sikh

    Paraminder

    Supreme God of Heaven

  • Meharprem
  • Boy/Male

    Indian, Punjabi, Sikh

    Meharprem

    Kind Love

  • Freny | ப்ரேநீ  
  • Girl/Female

    Tamil

    Freny | ப்ரேநீ  

    Foreigner

  • Arwydd
  • Girl/Female

    Welsh

    Arwydd

    Sign.

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Other words and meanings similar to

GI ALPHA-SUBUNIT

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  • Alpha
  • n.

    The first letter in the Greek alphabet, answering to A, and hence used to denote the beginning.

  • Alpia
  • n.

    The seed of canary grass (Phalaris Canariensis), used for feeding cage birds.

  • Alpist
  • n.

    Alt. of Alpia

  • Lyra
  • n.

    A northern constellation, the Harp, containing a white star of the first magnitude, called Alpha Lyrae, or Vega.

  • Omega
  • n.

    The last letter of the Greek alphabet. See Alpha.

  • Privative
  • a.

    Implying privation or negation; giving a negative force to a word; as, alpha privative; privative particles; -- applied to such prefixes and suffixes as a- (Gr. /), un-, non-, -less.

  • Pentalpha
  • n.

    A five-pointed star, resembling five alphas joined at their bases; -- used as a symbol.