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Enzyme found in humans
Furin is a protease, a proteolytic enzyme activated by substrate presentation that in humans and other animals is encoded by the FURIN gene. Some proteins
Furin
Japanese wind chimes
A fūrin (風鈴, ふうりん, lit. 'wind-bell') is a small, bowl-shaped Japanese wind chime typically hung during the summer. A piece of paper called tanzaku (短冊)
Fūrin
Japanese TV series
Fūrin Kazan (風林火山) is the 46th NHK Taiga drama television series that began on January 7, 2007. It was aired throughout 2007, with the last episode aired
Fūrin_Kazan_(TV_series)
Japanese manga series
Furin Shokudō (不倫食堂; lit. 'The Adultery Diner') is a Japanese manga series written and illustrated by Masakazu Yamaguchi. It was serialized in Shueisha's
Furin_Shokudō
War banner of Japanese daimyo Takeda Shingen
"Fuurinkazan" in his album "Byakko Kasuga Hachirou no Subete Original Hit Vol.3". Fūrin Kazan (TV series) 鈴木眞哉 (2009). "「風林火山」の旗印の怪しさ" [Historicity of the fūrinkazan
Fūrinkazan
Japanese actor
Hirotaka Shimazawa (島沢 弘隆, Shimazawa Hirotaka), better known by his stage name Chafurin (茶風林, Chafūrin) is a Japanese actor and narrator who is affiliated
Chafurin
Japanese manga series and its adaptations
fighter, which is now the only thing he prides himself on. After enrolling at Furin High School, where it is rumored that strength is valued over academics
Wind_Breaker_(manga)
Proposed theory on the origins of COVID-19
cytosine-guanine-guanine (CGG) codons in the virus' RNA, more precisely in the crucial furin cleavage site. The CGG codon is one of several codons that translates into
COVID-19_lab_leak_theory
Japanese annual drama series
times, the dramas are adapted from a novel (e.g. Fūrin Kazan is based on The Samurai Banner of Furin Kazan). Though taiga dramas have been regarded by
Taiga_drama
1996 Japanese film
Adultery Diary: One More Time While I'm Still Wet (不倫日記 濡れたままもう一度, Furin nikki: nureta mama mō ichidō) is a 1996 Japanese pink film directed by Toshiki
Adultery Diary: One More Time While I'm Still Wet
Adultery_Diary:_One_More_Time_While_I'm_Still_Wet
Virus that causes COVID-19
site cleaved by furin, which appears to be an important element enhancing its virulence. It was suggested that the acquisition of the furin-cleavage site
SARS-CoV-2
Class of enzymes
chains and activate the protein. The prototypical proprotein convertase is furin. Proprotein convertases have medical significance, because they are involved
Proprotein_convertase
Twitter group investigating COVID-19 origins
controversial DEFUSE proposal, which suggested inserting human-specific furin cleavage sites into bat coronaviruses. In 2021, DRASTIC's work led to heightened
DRASTIC
1969 Japanese film
Hepburn: Fūrin Kazan) is a Japanese samurai drama film released in 1969. It was directed by Hiroshi Inagaki and is based on the novel Furin kazan by Yasushi
Samurai_Banners
Temple in Ogori, Fukuoka Prefecture, Japan
fūrin (風鈴) are hung up at the temple during the summer. Visitors can buy a fūrin for 500 yen, write their wishes on the paper hanging from the fūrin,
Nyoirin-ji_(Ogori)
Indian health activist (died 2018)
Jennifer Furin (30 March 2019). "TB Killed Shreya Tripathi, But Her Death Could Have Been Avoided". The Wire. Stephen Lewis and Jennifer Furin (24 March
Shreya_Tripathi
Species of flowering plant
The hardiest of Enkianthus species is E. campanulatus (furin-tsutsuji or redvein enkianthus), a medium-sized, narrow, upright, deciduous shrub. Its bright
Enkianthus_campanulatus
Protein domain implicated in human brain evolution
human-specific Olduvai domains are post-translationally processed by the furin protease, with a cleavage site occurring once at each triplet. These results
Olduvai_domain
Japanese manga series
Voiced by: Natsumi Fujiwara The eldest son of Goro Shigeno and captain of Fūrin Middle School's baseball club. Hikaru Satō (佐藤 光, Satō Hikaru) Position:
Major_2nd
Cellular process in embryonic development
generate a mature Nodal. The subtilisin-like proprotein convertases (SPC) Furin (Spc1) and PACE4 (Spc4) recognize a specific sequence of the precursor of
Nodal_signaling_pathway
Percussion instrument constructed by rods, bells, tubes suspended in air
roofs; they are not limited to pagodas. Japanese glass wind bells known as fūrin (風鈴) have been produced since the Edo period, and those at Mizusawa Station
Wind_chime
Japanese actress (born 1975)
In 2007, she landed a role as a Shinobi (Ninja) in the NHK Taiga Drama Fūrin Kazan. Her performance as well as her expertise in sword-action fascinated
Juri_Manase
Virus that causes SARS
hemaglutinin (HE), first identified in 2003, and the viral spike protein lacks a furin cleavage site. Human SARS-CoV-1 appears to have had a complex history of
SARS-CoV-1
Japanese actor (born 2000)
Night Takahiro Ise A Light in the Harbor Kota (adult) Wind Breaker Legendary Furin Student 2026 Golden Kamuy: The Abashiri Prison Raid Hyakunosuke Ogata
Gordon_Maeda
Japanese singer-songwriter and actor (born 1973)
Saitama, and TV series most notably as Uesugi Kenshin in the NHK drama Fūrin Kazan. He also performed live in theatre stage plays, Nemuri Kyoshiro Buraihikae
Gackt
January 15, 1980 (1980-01-15) 246 "Dream Wind Chime" Transliteration: "Yume Fūrin" (Japanese: ゆめふうりん) January 16, 1980 (1980-01-16) Doraemon is ashamed when
List of Doraemon (1979 TV series) episodes (1979–1986)
List_of_Doraemon_(1979_TV_series)_episodes_(1979–1986)
2020 letter on the origins of COVID-19
humans. The spike protein of SARS-CoV-2 interacts with furin, an enzyme found in human cells. Furin-like sites are present in other viruses such as HIV and
The proximal origin of SARS-CoV-2
The_proximal_origin_of_SARS-CoV-2
Japanese actor and model
Year Title Role Notes Ref. 2005 Densha Otoko Naoto Oikawa 2007 Fūrin Kazan Yamagata Masakage Taiga drama 2013 Hanzawa Naoki Motoki Tamiya 2014 Dear Sister
Yasuyuki_Maekawa
Japanese singer-songwriter
"Again and Again" were used as the openings for Japanese TV dramas Gisou Furin and Joker x Face respectively, while her songs "Drown", and "Prover"/"Tell
Milet_(singer)
Japanese actor (born 1989)
Sakamoto: Rōdoku Geki Ni Rei Jū Shi Fuki no Hatsukoi, Ebina SA Kalashnikov Furin Kaikyō Hi no yō ni samishī Ane ga ite 2015 Hamlet Rareities Yoru e no Nagai
Shinnosuke_Mitsushima
Glycoprotein spike on a viral capsid or viral envelope
receptor binding, or the spike protein may be pre-cleaved such as by Furin at a furin cleavage site if one is present. Like other class I fusion proteins
Coronavirus_spike_protein
Public university in Akungba-Akoko, Nigeria
polypharmacology against SARS-CoV-2 drug targets: in vitro validation of furin inhibition" which resulted into the findings that Aframomum melegueta shows
Adekunle_Ajasin_University
District located in Shinjuku-ku, Tokyo
business with a cabaret[citation needed]; Lin Tsai-wang, who built the Fūrin Kaikan; and Lee Ho-chu, owner of the Tokyo Hotel Chinese restaurant. In
Kabukichō
2026 Japanese TV series or program
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
Brothers_in_Arms_(TV_series)
Protein-coding gene in the species Homo sapiens
their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth
SNX15
Japanese samurai and daimyo (1521–1573)
on a novel by Inoue Yasushi titled Furin Kazan. Shingen's life is also dramatized in NHK's 46th Taiga drama Fūrin Kazan, which depicts the life of his
Takeda_Shingen
Protein-coding gene in the species Homo sapiens
24-amino acid N-terminal signal peptide, creating a 60-amino acid prohepcidin. Furin-like convertase and α-1 antitrypsin then cleave prohepcidin to remove a
Hepcidin
Japanese manga artist
Yukibana no Tora (雪花の虎) (2015–2020, Shogakukan) A Fake Affair (偽装不倫, Gisō Furin) (2017–2019, Bungeishunjū) Tokyo Tarareba Girls Extra Edition: Tarare-Bar
Akiko_Higashimura
2023 Japanese television series
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
What_Will_You_Do,_Ieyasu?
Japanese actor (born 1993)
Abaranger (2003), Lad Tokusou Sentai Dekaranger (2004), Hikaru Hiwatari Fūrin Kazan (2007), Yokichi Kuzurasa Maō (2008), Hitoshi Kasai (young) Karyū no
Yūto_Uemura
Japanese actor and martial artist (1939–2021)
initials stood for "Justice Japan". After appearing in the taiga drama Fūrin Kazan in November 2007, he announced the retirement of the stage name "Shinichi
Sonny_Chiba
Japanese manga series
give her a suppository. 2 "Second Period" Transliteration: "Amayadori/ fūrin-jiru" (Japanese: 雨宿り / 風梨汁) Kazuhiko Tamura, Toshimitsu Kobayashi, Yuichiro
Why the Hell Are You Here, Teacher!?
Why_the_Hell_Are_You_Here,_Teacher!?
1991 taiga drama about Shogun Ahikaga Takauji
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
Taiheiki_(TV_series)
Rampu" (Japanese: 怪談ランプ) 19 19 "Dream Wind Chime" Transliteration: "Yume Fūrin" (Japanese: ゆめふうりん) 26 August 2005 (2005-08-26) "The Change of Clothes Camera"
List of Doraemon (2005 TV series) episodes (2005–2014)
List_of_Doraemon_(2005_TV_series)_episodes_(2005–2014)
Japanese writer (born 1964)
in 2000, she received the 10th Bunkamura Deux Magots Literary Prize, for Furin to Nambei, a collection of stories set in South America. Outside Japan,
Banana_Yoshimoto
Strain of SARS-related coronavirus
Other researchers have questioned the validity of this as an authentic furin cleavage site insertion, noting that it appears more likely to be a deletion
RmYN02
2015 studio album by Wagakki Band
"Recollection")) Machiya 5:16 5. "Hagane" ((鋼-HAGANE-; "Steel")) Kurona 4:23 6. "Fūrin no Utautai" ((風鈴の唄うたい; "Sing with the Wind Chimes")) Yuko Suzuhana 4:44
Yasō_Emaki
Shinto shrine
the months of July, August and September, thousands of wind chimes called fūrin with one's wishes written on wooden plaques are displayed. "Love Blessing
Hikawa_Shrine_(Kawagoe)
Japanese manga magazine
Love (ねずみの初恋) Riku Ooseto November 2023 Official Adultery? (公式不倫, Kōshiki Furin) Nikumaru February 2026 Parallel Paradise (パラレルパラダイス) Lynn Okamoto March
Weekly_Young_Magazine
Japanese actor
Hideharu Ohtake 2006–14 Team Medical Dragon Keisuke Fujiyoshi 4 seasons 2007 Fūrin Kazan Sanada Yukitaka Taiga drama Bambino! Atsushi Kuwabara 2008 Saitō-san
Kuranosuke_Sasaki
2017 compilation album by Wagakki Band
~Sky Lantern~)) 2. "Kyoto Higashiyama (Shigin)" ((京都東山(詩吟))) 3. "Fūrin no Utautai" ((風鈴の唄うたい; "Sing with the Wind Chimes")) Suzuhana 4. "Iroha
Kiseki_Best_Collection_+
First age of the Late Triassic epoch
Mietto, Paolo; Manfrin, Stefano; Preto, Nereo; Rigo, Manuel; Roghi, Guido; Furin, Stefano; Gianolla, Piero; Posenato, Renato; Muttoni, Giovanni; Nicora,
Carnian
European comics award
'diverso' attraverso il fumetto americano (1930-1940) (1982-1983) Elena Furin I fumetti di Frigidaire (1983-1984) 1986 Francesca Camera Alexandre Alexeieff
Yellow_Kid_Award
August 6, 2022 (2022-08-06) 1305 "Dream Wind Chime" Transliteration: "Yume no fūrin" (Japanese: 夢の風鈴) Unknown Unknown August 6, 2022 (2022-08-06) 1306 "Winning
List of Doraemon (2005 TV series) episodes (2015–2024)
List_of_Doraemon_(2005_TV_series)_episodes_(2015–2024)
Human retrovirus, cause of AIDS
reticulum and is transported to the Golgi apparatus where it is cleaved by furin resulting in the two HIV envelope glycoproteins, gp41 and gp120. These are
HIV
1984 Japanese TV series or program
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
Sanga_Moyu
1976 Japanese TV series or program
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
Kaze_to_Kumo_to_Niji_to
Japanese actor and musician (born 1969)
Year Title Role Notes Ref. 2000 Aoi Ōno Harufusa Taiga drama 2007 Fūrin Kazan Baba Nobuharu Taiga drama 2012 Victory in Defeat Eisaku Satō 2016 Sanada
Kazuya_Takahashi
Family of zinc-dependent metalloendopeptidases
sequence PRCGxPD. Some MMPs have a prohormone convertase cleavage site (Furin-like) as part of this domain, which, when cleaved, activates the enzyme
Matrix_metalloproteinase
American voice actress
Yogiri (young) 2024 Wistoria: Wand and Sword Narrator 2024 Dungeon People Furin 2025 Loner Life in Another World Handicraft Girl 2025 Hero Without a Class:
Shannon_Emerick
2014 taiga drama about Kuroda Kanbei
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
Gunshi_Kanbei
Protein-coding gene in the species Homo sapiens
common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded
R-spondin_4
proposals. Within genus Betacoronavirus, furin cleavage sites are common in subgenera Merbecovirus and Embecovirus. Furin cleavage sites have independently evolved
Zoonotic_origins_of_COVID-19
Japanese commander
he was played by Ryūnosuke Tsukigata, and in the 2007 television series Fūrin Kazan.[citation needed] Turnbull 2003, p. 29. Turnbull 2002, pp. 35, 58
Kasahara_Kiyoshige
Japanese actress
Lecherous Family: Immoral, Lusty Widow いんらん家族 好色不倫未亡人 Inran kazoku: kōshoku furin mibōjin 1997-12-26 Akira Fukamachi Shintōhō Eiga 60 min. With Yutaka Ikejima
Megumi_Makihara
Japanese composer, arranger and conductor
Rampo, Strawberry on the Shortcake, Yomigaeri, Red Garden, Nada Sōsō, Fūrin Kazan, Fullmetal Alchemist: Brotherhood, Tales of Vesperia: The First Strike
Akira_Senju
2009 single by Gackt
song on the single, "My Father's Day" was written in memory of Gackt's Fūrin Kazan co-actor and close friend, Ken Ogata. On its record jacket, "Koakuma
Koakuma_Heaven
2022 taiga drama about Hōjō Yoshitoki
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
The_13_Lords_of_the_Shogun
2012 single by AKB48
Onchi" (Type A) "Nante Bohemian" (Type B) "Show fight!" (Type B) "Ano Hi no Fūrin" (Theater Edition) Released August 29, 2012 (2012-08-29) (Japan) Genre J-pop
Gingham_Check
2025 Japanese TV series
Musashi (2003) Shinsengumi! (2004) Yoshitsune (2005) Kōmyō ga Tsuji (2006) Fūrin Kazan (2007) Atsuhime (2008) Tenchijin (2009) 2010s Ryōmaden (2010) Gō (2011)
Unbound_(TV_series)
Viral disease
immature particles are processed in the Golgi apparatus by the host protein furin, which cleaves prM to M. This releases E from the complex, which can now
Yellow_fever
Second epoch of the Triassic period
Mietto, Paolo; Manfrin, Stefano; Preto, Nereo; Rigo, Manuel; Roghi, Guido; Furin, Stefano; Gianolla, Piero; Posenato, Renato; Muttoni, Giovanni; Nicora,
Middle_Triassic
Japanese manga series
Jones (English) The chief of the thieves' guild. He used to be an assassin. Fūrin (フーリン) Voiced by: M.A.O (Japanese); Shannon Emerick (English) The chief
Dungeon_People
Protein-coding gene in humans
activation of human adamalysin 19/disintegrin and metalloproteinase 19 by furin occurs via one of the two consecutive recognition sites". The Journal of
ADAM19
Japanese actor and singer
Kaidō Maru (2024), Tsuchiya Paris ni Saku Étoile (2026), Ruslan (voice) Fūrin Kazan (2007) – Hōjō Ujimasa Shinzanmono (2010) – Kazuhiro Uesugi Miss Double
Taichi_Saotome
Rihoko and followed her, secretly listens. 4 "Wind Chime" Transliteration: "Fūrin" (Japanese: フウリン) Rihoko Sakurai arc 2nd Half January 26, 2012 (2012-01-26)
List_of_Amagami_SS_episodes
Japanese samurai (1525-1561)
Retrieved 23 October 2021. Inoue, Yasushi. (2006). The Samurai banner of Furin Kazan, p. 7. Turnbull, Stephen (1987). Battles of the Samurai. Arms and
Takeda_Nobushige
Indian lawyer
lawyer Anand Grover". in.news.yahoo.com. Retrieved 2019-06-26. Jennifer Furin (30 March 2019). "TB Killed Shreya Tripathi, But Her Death Could Have Been
Anand_Grover
Japanese pornographic actress (born 1992)
Atsui Natsu no Sei...Dōsōkai de Saikai shita Motokare to hito Natsu no Furin ni Ochi Ase o Karamase Nando mo Kairaku o Motometa Hitozuma (7 Sep, SOD
Iori_Kogawa
Mammalian protein found in humans
identical in all three chains. Furthermore, possible recognition sequences for furin (a major physiological protease) cleavage sites have been found in both
Collagen,_type_XXIII,_alpha_1
Glycoprotein exposed on the surface of the HIV virus
(~345 amino acids) in the endoplasmatic reticulum by the cellular protease furin. The crystal structure of core gp120 shows an organization with an outer
Envelope_glycoprotein_GP120
Recall election in US state
1%; Lozano, Collins, Newman, Lodge, Richter, Martinez, Gallucci, Symmon, Furin, Le Roux, Stephens, Hillberg, Kaul, Hanink, Papagan, Marciniak, Lucey, Killens
2021 California gubernatorial recall election
2021_California_gubernatorial_recall_election
Soft-matter theorist
decreased by mutating or blocking the polybasic cleavage site (known as the furin cleavage site), providing a mechanism to decrease COVID 19 infection, as
Monica_Olvera_de_la_Cruz
Japanese film director, actress and screenwriter
first pink film, Chronic Rutting Adultery Wife (まん性発情不倫妻, Mansei hatsujō furin-zuma). At the Pink Grand Prix she was given a Best New Director award for
Yumi_Yoshiyuki
Japanese actor (born 1963)
Shakedown: N.E.W (2026), Joichiro Kijima Kaiji 4 (2027), Kozo Nonomura Fūrin Kazan (2007), Akabe Shimotsuke-no-kami Sanada Maru (2016), Ideura Masasuke
Susumu_Terajima
Japanese actor and voice actor (born 1949)
Hideyoshi (1996) – Kuroda Kanbei The Great White Tower (2003) – Professor Ugai Fūrin Kazan (2007) – Taigen Sessai Detective Conan (2011) Crime and Punishment:
Masatō_Ibu
Topics referred to by the same term
Pacing and Clinical Electrophysiology, a peer-reviewed medical journal Furin or paired basic amino acid cleaving enzyme, a protein in humans Program
PACE
Species of flavivirus causing West Nile fever
immature virions. The E protein is then glycosylated and prM is cleaved by furin, a host cell protease, into the M protein, thereby producing an infectious
West_Nile_virus
Japanese manga series
2024 (2024-05-22) 8 "A Book, An Affair, and a Mermaid" Transliteration: "Hon to Furin to Ningyohime" (Japanese: 本と不倫と人魚姫) Rei Mano Yoshitaka Yasuda May 29, 2024 (2024-05-29)
Mysterious_Disappearances
Japanese actor (born 1980)
Park Masa Mori 2002 Kisarazu Cat's Eye Shingo "Master" Okabayashi 2007 Fūrin Kazan Heizo Yazaki Taiga drama 2008 Rookies Koichi Kawato Lead role 2016
Ryuta_Sato
North Carolina State University. Gu, Zhen; et al. (December 15, 2014). "Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug
Potential applications of graphene
Potential_applications_of_graphene
Protein-coding gene in the species Homo sapiens
00049.2003. PMID 12709393. Wu C, Wu F, Pan J, Morser J, Wu Q (July 2003). "Furin-mediated processing of Pro-C-type natriuretic peptide". The Journal of Biological
Natriuretic peptide precursor C
Natriuretic_peptide_precursor_C
Protein family
families has been proposed. The proprotein-processing endopeptidases kexin, furin and related enzymes form a distinct subfamily known as the kexin subfamily
Subtilase
Species of virus affecting humans and animals
protein VP40 Q05128 Matrix. GP Envelope glycoprotein Q05320 Cleaved by host furin into GP1/2 to form envelope with spikes. Also makes shed GP as a decoy.
Zaire_ebolavirus
American physiologist and Nobel laureate 2021
and Randy Schekman, where he identified Kex2 as the founding member of furin-like proprotein convertases. In 1989, he completed his post-doctoral training
David_Julius
Japanese actor (born 1986)
Shunichiro Koma 2007 Tokyo Tower: Mom and Me, and Sometimes Dad Kohei Yamada Fūrin Kazan Chōkyū Taiga drama Aoi Hitomi to New Age Keiichi Zaizen 2008 Shin
Tasuku_Emoto
Type of coronavirus detected in 2021
deletions in other genomic regions. For example, three mutations at the furin cleavage site, which facilitates its transmission. A 2025 study demonstrated
SARS-CoV-2_Omicron_variant
British former intelligence officer (born 1945)
based on the furin cleavage site, and describes unusual features in the virus’s spike protein, such as positively charged inserts and a furin-like cleavage
Richard_Dearlove
Japanese actress and tarento (born 1993)
Fukiko Saigo 2007 GoGo Sentai Boukenger – Episode 47-49 Leon Giordana 2007 Fūrin Kazan – Episode 8, 26, 36 Miruhime (young) 2007 Joudan Ja Nai! Seren Hirose
Rio_Kanno
Japanese actress
Stella Next to Me (2025), Chie Amano Tokugawa Yoshinobu (1998), Oyoshi Fūrin Kazan (2007), Shinome 1991, won Japan Academy Film Prize for 'Newcomer of
Misa_Shimizu
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