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Chemical compound
Fosfomycin, sold under the brand name Monurol among others, is an antibiotic primarily used to treat lower urinary tract infections. It is not indicated
Fosfomycin
Medication for urinary tract infections
20th century. Nitrofurantoin, trimethoprim-sulfamethoxazole (TMP/SMX), fosfomycin, and pivmecillinam are currently the first-line agents for empiric therapy
Urinary_anti-infective_agent
Antibacterial drug
effectiveness of nitrofurantoin for 5 days is equivalent to that with single-dose fosfomycin. As a prophylactic against UTIs, nitrofurantoin was similarly effective
Nitrofurantoin
Antibiotic-resistant bacteria
bacterial isolates were susceptible to fosfomycin.[citation needed] The elevated level of antimicrobial activity by fosfomycin can be attributed to the fact that
Carbapenem-resistant enterobacteriaceae
Carbapenem-resistant_enterobacteriaceae
Combination antibiotic medication
trimethoprim/sulfamethoxazole, 92% and 87% for nitrofurantoin, 91% and 83% for fosfomycin, 90% and 91% for fluoroquinolones (ciprofloxacin and norfloxacin), and
Amoxicillin/clavulanic_acid
Infection that affects part of the urinary tract
by mouth such as nitrofurantoin, pivmecillinam, or fosfomycin are typically first line. Fosfomycin may be used as a single dose, whereas nitrofurantoin
Urinary_tract_infection
Combination drug
Fosfomycin/tobramycin is a formulation of fosfomycin and tobramycin. Fosfomycin is a phosphonic acid antibiotic active against gram-positive and gram-negative
Fosfomycin/tobramycin
Inflammation of the kidney
chosen, single daily dosing with aminoglycosides is safe and effective. Fosfomycin can be used as an efficacious treatment for both UTIs and complicated
Pyelonephritis
Antibiotic
Chloramphenicol has been demonstrated a synergistic effect when combined with fosfomycin against clinical isolates of Enterococcus faecium. Chloramphenicol is
Chloramphenicol
Species of bacterium
macrolides, quinolones, tetracyclines, aminoglycosides, glycopeptides, and fosfomycin (see table in Genome structure), and multidrug resistance is common. As
Staphylococcus_haemolyticus
Antiretroviral medication
isolates), especially in combination with other active agents (e.g., fosfomycin, colistin, tigecycline). Most common side effects include nausea, vomiting
Zidovudine
Organic compound with at least one covalent carbon–phosphorus bond
phosphinates in the order shown: Sarin (phosphonate), Glyphosate (phosphonate), fosfomycin (phosphonate), zoledronic acid (phosphonate), and Glufosinate (phosphinate)
Organophosphorus_chemistry
Chemical compound
peptidoglycan strands of the cell wall. Synthesis of NAM is inhibited by fosfomycin. NAG and NAM cross-linking can be inhibited by antibiotics to inhibit
N-Acetylmuramic_acid
Pharmaceutical drug
tested as partner drugs of oritavancin. Among these "companions" drugs, fosfomycin displayed (in vitro and in vivo) synergistic activity when administered
Oritavancin
Genus of bacteria
Chloramphenicol (from S. venezuelae) Daptomycin (from S. roseosporus) Fosfomycin (from S. fradiae) Lincomycin (from S. lincolnensis) Neomycin (from S.
Streptomyces
Chemical compound
redox balance and plays a role in microbial resistance to the antibiotic fosfomycin. Chemically, it is a glycoside formed between L-cysteinyl-D-glucosamine
Bacillithiol
Species of bacterium
first-generation and second-generation cephalosporins, macrolides, lincosamides, fosfomycin, colistin, and polymyxin B. The emergence of highly resistant strains
Morganella_morganii
Species of bacterium
fradiae are known to produce the antibiotics neomycin, tylosin, and fosfomycin. Deutsche Sammlung von Mikroorganismen und Zellkulturen [1] Woodyer RD
Streptomyces_fradiae
Species of bacterium
Streptomyces wedmorensis produces (S)-2-hydroxypropylphosphonic acid epoxidase, fosfomycin and phosphonomycin B. List of Streptomyces species LPSN bacterio.net Straininfo
Streptomyces_wedmorensis
amoxicillin 1972 – cefradine 1972 – minocycline 1972 – pristinamycin 1973 – fosfomycin 1974 – talampicillin 1975 – tobramycin 1975 – bacampicillin 1975 – ticarcillin
Timeline_of_antibiotics
Class of enzymes
fosfomycin (S)-2-hydroxypropylphosphonic acid epoxidase contains one non-heme iron centre per monomer. The product is the antibiotic fosfomycin. Yan
(S)-2-hydroxypropylphosphonic acid epoxidase
(S)-2-hydroxypropylphosphonic_acid_epoxidase
Bacterial strains of Enterococcus that are resistant to the antibiotic vancomycin
linezolid is commonly used to treat VRE. The combination of linezolid and fosfomycin has been reported to show synergistic activity against VRE. Similar findings
Vancomycin-resistant Enterococcus
Vancomycin-resistant_Enterococcus
Sexually transmitted infection
Wind CM, Boyd A, et al. (May 2022). "Efficacy of ertapenem, gentamicin, fosfomycin, and ceftriaxone for the treatment of anogenital gonorrhoea (NABOGO):
Gonorrhea
Antimicrobial substance active against bacteria
combined effect of both antibiotics is better than their individual effect. Fosfomycin has the highest number of synergistic combinations among antibiotics and
Antibiotic
Organic compound containing C–PO(OR)2 groups
have been identified. Phosphonate natural product antibiotics include fosfomycin which is approved by FDA for the treatment of non-complicated urinary
Phosphonate
Medical intervention
clindamycin 16 days dextrose 5% No flucloxacillin 24 hours normal saline Yes fosfomycin 24 hours water for injection No oxacillin 24 hours normal saline No benzylpenicillin
Outpatient parenteral antibiotic therapy
Outpatient_parenteral_antibiotic_therapy
Bacterial infection of the prostate gland
second-line antibiotics and azithromycin is reserved for special situations. Fosfomycin has also been repurposed for chronic bacterial prostatitis and is increasingly
Chronic_bacterial_prostatitis
Species of bacterium
identification of Staphylococcus epidermidis using desferrioxamine and fosfomycin disks". APMIS. 116 (1): 16–20. doi:10.1111/j.1600-0463.2008.00796.x. PMID 18254775
Staphylococcus_epidermidis
Categorization scheme for antibiotics
mouth and by injection), and linezolid. The intravenous formulation of fosfomycin is reserve while the by mouth formulation is watch. About 10% of this
WHO_AWaRe
bacterial protein synthesis by binding to the 50S subunit of the ribosome Fosfomycin Monurol, Monuril Acute cystitis in women This antibiotic is not recommended
List_of_antibiotics
Spanish researcher and microbiologist
discover various active principles, such as the broad-spectrum antibiotic Fosfomycin, widely used in the treatment of urinary tract infections and other ailments
Sagrario_Mochales
Species of bacterium
Chloramphenicol (Streptomyces venezuelae) Daptomycin (Streptomyces roseosporus) Fosfomycin (Streptomyces fradiae) Lincomycin (Streptomyces lincolnensis) Neomycin
Streptomyces_isolates
Chemical compound
β-lactam antibiotics, aminoglycosides, tetracycline, chloramphenicol, fosfomycin, etc. Plasmids carrying these genes readily move between strains or between
Darobactin
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Side_effects_of_penicillin
Combination antibiotic medication
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Aztreonam/avibactam
Antibiotic medication
Wind CM, Boyd A, et al. (May 2022). "Efficacy of ertapenem, gentamicin, fosfomycin, and ceftriaxone for the treatment of anogenital gonorrhoea (NABOGO):
Ertapenem
Class of enzymes
peptide portion of peptidoglycan. The enzyme is inhibited by the antibiotic fosfomycin, which covalently modifies an active site cysteine residue. This enzyme
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
UDP-N-acetylglucosamine_1-carboxyvinyltransferase
Class of antibacterial drugs, subgroup of quinolones
lower compared to antibiotics such as tetracyclines, daptomycin, and fosfomycin, which demonstrate greater efficacy against biofilms. Fluoroquinolones
Quinolone_antibiotic
Class of enzymes
quinolones and sulfonamides. Treatment options may include nitrofurantoin, fosfomycin, mecillinam and chloramphenicol. In desperation, once-daily ertapenem
Beta-lactamase
Pharmaceutical drug classification
Furazolidine QJ01XE91 Nifurpirinol QJ01XQ01 Tiamulin QJ01XQ02 Valnemulin J01XX01 Fosfomycin J01XX02 Xibornol J01XX03 Clofoctol J01XX04 Spectinomycin J01XX05 Methenamine
ATC_code_J01
Class of highly effective antibiotic agents
resistance trends and mechanisms for the old antibiotics colistin, temocillin, fosfomycin, mecillinam and nitrofurantoin". Clin. Microbiol. Infect. 21 (10): 899–905
Carbapenem
Antibiotic
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Benzathine_benzylpenicillin
Microbe with cell wall mostly removed
spheroplasts. These include peptidoglycan synthesis inhibitors such as fosfomycin, vancomycin, moenomycin, lactivicin and the β-lactam antibiotics. Antibiotics
Spheroplast
Former pharmaceutical company merged with Allergan
constipation-predominant irritable bowel syndrome and functional constipation Monurol (fosfomycin) for certain urinary tract infections Namenda and Namenda XR (memantine)
Forest_Laboratories
(INN) fosfestrol (INN) fosfluridine tidoxil (INN) fosfocreatinine (INN) fosfomycin (INN) fosfonet sodium (INN) fosfosal (INN) fosinopril (INN) fosinoprilat
List_of_drugs:_Fm–Ft
Pharmaceutical drug classification
Miconazole S02AA14 Gentamicin S02AA15 Ciprofloxacin S02AA16 Ofloxacin S02AA17 Fosfomycin S02AA18 Cefmenoxime S02AA30 Antiinfectives, combinations QS02AA57 Neomycin
ATC_code_S02
Species of bacterium
expression of AdeABC. Disruption of abaF has displayed an increase in fosfomycin susceptibility and a decrease in biofilm formation and virulence, suggesting
Acinetobacter_baumannii
Chemical compound
synergistic activity has been demonstrated when administered alongside fosfomycin. Temocillin has also been reported in the management of urinary tract
Temocillin
Species of bacterium
lincomycin and clindamycin), streptogramins, rifampicin, fusidic acid, and fosfomycin. P. gergoviae is also resistant to cefoxitin, likely due to β-lactamase
Pluralibacter_gergoviae
Gram-negative bacteria with resistance to multiple antibiotics
the revisit of old antibiotic drugs such as colistin (Polymyxins) and fosfomycin, which are traditionally considered to be toxic but have gained a principal
Multidrug-resistant Gram-negative bacteria
Multidrug-resistant_Gram-negative_bacteria
Protein-coding gene in the species Homo sapiens
resembles several proteins that allow bacteria to resist antibiotics such as fosfomycin, bleomycin and mitomycin. Likewise, the unrelated enzymes methylmalonyl-CoA
Lactoylglutathione_lyase
Antibiotic medication
2013). "Peptide antibiotics: polymyxins, glycopeptides, bacitracin, and fosfomycin.". In Giguère S, Prescott JF, Dowling PM (eds.). Antimicrobial Therapy
Piperacillin
Combination antibiotic drug
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Ampicillin/sulbactam
Particular type of emulsion
Antibacterial Potential of Greenly Synthesized Silver Nanoparticles with Fosfomycin Against Some Nosocomial Bacterial Pathogens". Infection and Drug Resistance
Miniemulsion
thiophosphoric acid esters MeSH D02.705.539.950 – thiotepa MeSH D02.705.639.250 – fosfomycin MeSH D02.705.639.590 – phosphonoacetic acid MeSH D02.705.639.590.500 –
List_of_MeSH_codes_(D02)
American microbiologist (1927–2020)
monosodium glutamate, vitamin B12, streptomycin, riboflavin, cephamycin, fosfomycin, and interferon inducers," and "elucidated the mechanism by which the
Arnold_Demain
Chemical compound
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Avibactam
system. RalR/RaLA TA locus is responsible for resistance to the antibiotic fosfomycin in E.coli. Deep sequencing of RNA expressed during chemical stress and
Escherichia_coli_sRNA
Species of bacterium
clindamycin, colistin sulphate, enrofloxacin, erythromycin, florfenicol, fosfomycin, fusidic acid, gentamicin, kanamycin, lincomycin, neomycin, nitrofurantoin
Staphylococcus_nepalensis
Chemical compound
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Cefozopran
Chemical compound
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Epicillin
Chemical compound
Inhibit PG subunit synthesis and transport: NAM synthesis inhibition Fosfomycin DADAL/AR inhibitors Cycloserine Terizidone bactoprenol inhibitors Bacitracin
Carumonam
Enzyme
synthesis of phosphonates, such as phosphonolipids and the antibiotics fosfomycin and bialaphos. The formation of this bond is quite thermodynamically unfavorable;
Phosphoenolpyruvate_mutase
FOSFOMYCIN
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Male
Italian
Italian form of Latin Callistus, CALLISTO means "most beautiful." Compare with feminine Callisto.
Boy/Male
Hindu, Indian, Punjabi, Sikh, Telugu
King of God / Lord
Girl/Female
Indian, Punjabi, Sikh
Shimmer
Girl/Female
African, American, Australian, British, English, German
Bright Meadow
Boy/Male
Arabic, Muslim
Brave; Fearless
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Hindu, Indian
Name of a Place
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Female
Japanese
(æ „å) Japanese name EIKO means "long-lived child" or "splendid child."
Boy/Male
Hindu
Veda
Boy/Male
Arabic, Muslim
Care of the Most Gracious Allah
FOSFOMYCIN
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FOSFOMYCIN