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Malignant tumors composed of fibrous tissue
Fibrosarcoma (fibroblastic sarcoma) is a malignant mesenchymal tumour derived from fibrous connective tissue and characterized by the presence of immature
Fibrosarcoma
Cancer originating in connective tissue
cell tumors (includes Ewing sarcoma) Hemangioendothelioma Angiosarcoma Fibrosarcoma/myofibrosarcoma Chordoma Adamantinoma Other: Liposarcoma Leiomyosarcoma
Sarcoma
Benign tumors composed of fibrous or connective tissue
used without modifier, it is usually considered benign, with the term fibrosarcoma reserved for malignant tumors. The hard fibroma (fibroma durum) consists
Fibroma
Medical condition
Sclerosing epithelioid fibrosarcoma (SEF) is a very rare malignant tumor of soft tissues that on microscopic examination consists of small round or ovoid
Sclerosing epithelioid fibrosarcoma
Sclerosing_epithelioid_fibrosarcoma
Type of malignant tumor found in animals
vaccination to tumor formation varies from three months to eleven years. Fibrosarcoma is the most common VAS; other types include rhabdomyosarcoma, myxosarcoma
Injection-site_sarcoma
Medical condition
xanthomatous pseudotumor, solitary mast cell granuloma, inflammatory fibrosarcoma, pseudosarcomatous myofibroblastic proliferation, myofibroblastoma, inflammatory
Inflammatory myofibroblastic tumour
Inflammatory_myofibroblastic_tumour
kinase-related oncogene that enhances fibrosarcoma induction. RAF is an acronym for Rapidly Accelerated Fibrosarcoma. RAF kinases participate in the RAS-RAF-MEK-ERK
RAF_kinase
Tumors originating from fibroblast or muscle cell precursors
(i.e. leg and arm) areas. Infantile fibrosarcoma, also termed congenital infantile fibrosarcoma and fibrosarcoma, infantile type. Malignant FMTs Solitary
Fibroblastic and myofibroblastic tumors
Fibroblastic_and_myofibroblastic_tumors
Fibrosarcoma cell line
HT1080 is a fibrosarcoma cell line which has been used extensively in biomedical research. The cell line was created from tissue taken in a biopsy of a
HT1080
Human disease
small-round-cell tumor Skin sarcoma Connective tissue neoplasm Fibromatous Fibroma/fibrosarcoma Dermatofibrosarcoma protuberans Desmoplastic fibroma Fibroma/fibromatosis
Skin_sarcoma
Medical condition
ameloblastic fibrosarcoma in accord with the terminological distinction that reserves the word fibroma for benign tumors and assigns the word fibrosarcoma to malignant
Ameloblastic_fibroma
Rare cancer of the extremities, often near joints or tendon sheaths
Micrograph of a monophasic synovial sarcoma. The histologic appearance is non-specific and overlaps with MPNST and fibrosarcoma. H&E stain. Specialty Oncology
Synovial_sarcoma
Medical condition
from other mesenchymal tumors, particularly from sclerosing epithelioid fibrosarcoma (SEF). LGFMS tumors present with many clinical and pathological features
Low-grade_fibromyxoid_sarcoma
Protein-coding gene in the species Homo sapiens
Committee-approved gene name of MAFK is “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K”. MafK was first cloned and identified in chicken
MAFK
Protein-coding gene in the species Homo sapiens
Committee-approved gene name of MAFG is “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G”. MafG was first cloned and identified in chicken
MAFG
Protein-coding gene in the species Homo sapiens
Maf, also known as proto-oncogene c-Maf or V-maf musculoaponeurotic fibrosarcoma oncogene homolog, is a transcription factor that in humans is encoded
MAF_(gene)
Protein-coding gene in the species Homo sapiens
Transcription factor MafB also known as V-maf musculoaponeurotic fibrosarcoma oncogene homolog B is a protein that in humans is encoded by the MAFB gene
MAFB_(gene)
Dark pigment released by cephalopods
is being researched in mice for its antitumor activity against Meth-A fibrosarcoma. However, it currently remains unclear if any of the antitumor activity
Cephalopod_ink
Chemical compound
Acemannan is currently being used for treatment and clinical management of fibrosarcoma in dogs and cats. Administration of acemannan has been shown to increase
Acemannan
Any of the forms of odontogenic neoplasm
Ameloblastoma, a type of odontogenic tumor involving ameloblasts Ameloblastic fibrosarcoma Calcifying cystic odontogenic tumor Calcifying epithelial odontogenic
Odontogenic_tumor
Malignant tumors of soft tissues excluding skeletal muscle tissue
tumors Fibrosarcoma Infantile fibrosarcoma Myxofibrosarcoma Low-grade myofibroblastic sarcoma Sclerosing epithelioid fibrosarcoma Vascular tumors
Non-rhabdomyosarcoma soft tissue sarcomas
Non-rhabdomyosarcoma_soft_tissue_sarcomas
Genus of New World monkeys
C-Type Virus in Tumor Tissue of a Woolly Monkey (Lagothrix spp.) With Fibrosarcoma, JNCI: Journal of the National Cancer Institute, Volume 47, Issue 4,
Woolly_monkey
Vaccination of cats
Another uncommon reaction is the development of a vaccine-associated fibrosarcoma, a tumor at the injection site that develops months or years after vaccination
Feline_vaccination
Medical effects of tumors besides mass effect
(Parathyroid hormone-related protein), TGF-α, TNF, IL-1 Hypoglycemia Fibrosarcoma Other mesenchymal sarcomas Insulinoma Hepatocellular carcinoma Insulin
Paraneoplastic_syndrome
Translocation of genetic material
several types of cancers. It was originally identified in congenital fibrosarcoma and subsequently found in mammary secretory carcinoma (also termed juvenile
ETV6-NTRK3_gene_fusion
Chemical compound
cancer cell proliferation by an oxidative mechanism in the human HT-1080 fibrosarcoma cell line has been established. Caffeic acid is an antioxidant in vitro
Caffeic_acid
Felix Jacob Marchand (1846–1928), in whose department he described a fibrosarcoma of the ovary that was to become known as a Krukenberg tumor. In 1896
Friedrich_Ernst_Krukenberg
Perennial herb
antifungal and antimicrobial. Ethanol extract is cytotoxic against fibrosarcoma cell lines, ethyl acetate extract has antiproliferative properties against
Marjoram
Group of malignant tumors in cats and dogs
tumors that fall under the category of soft tissue sarcomas includes fibrosarcoma, hemangiopericytoma, liposarcoma, rhabdomyosarcoma, leiomyosarcoma, malignant
Soft tissue sarcoma in cats and dogs
Soft_tissue_sarcoma_in_cats_and_dogs
Lymphomas of primary cutaneous origin (e.g. mycosis fungoides) Angiosarcoma Fibrosarcoma Liposarcoma Malignant peripheral nerve sheath tumor Synovial sarcoma
List_of_cancer_types
Species of plant
with surgery and radiation therapy on spontaneous canine and feline fibrosarcomas". J Am Anim Hosp Assoc. 31 (5): 439–447. doi:10.5326/15473317-31-5-439
Aloe_vera
Protein-coding gene
Committee-approved gene name of MAFF is “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F”. MafF was first cloned and identified in chicken
MAFF_(gene)
Neck portion of a long bone between the epiphysis and the diaphysis
Metaphyseal tumors or lesions include osteosarcoma, chondrosarcoma, fibrosarcoma, osteoblastoma, enchondroma, fibrous dysplasia, simple bone cyst, aneurysmal
Metaphysis
Cancer originating in smooth muscle
diagnosis, which includes spindle cell carcinoma, spindle cell melanoma, fibrosarcoma, malignant peripheral nerve sheath tumor, and even biphenotypic sinonasal
Leiomyosarcoma
Abnormal growth of tissue within bone
bone sarcomas, include osteosarcoma, chondrosarcoma, Ewing sarcoma, fibrosarcoma, and other types. While malignant fibrous histiocytoma (MFH) - now generally
Bone_tumor
Class of proteins
Small Maf (musculoaponeurotic fibrosarcoma) proteins are basic region leucine zipper-type transcription factors that can bind to DNA and regulate gene
Small_Maf
Medical condition
myofibroblastic tumors. Histologically they resemble very low-grade fibrosarcomas, but they are very locally aggressive and tend to recur even after complete
Aggressive_fibromatosis
List of examples of in vivo transdifferentiation through transfection
(Pdx1) exocrine cells → B cells (Pdx1, Ngn3, and v-maf musculoaponeurotic fibrosarcoma oncogene family protein A) nonsensory cells → inner hair cells (Atoh1
Examples of in vivo transdifferentiation by lineage-instructive approach
Examples_of_in_vivo_transdifferentiation_by_lineage-instructive_approach
Process by which cells are grown under controlled conditions
Human Leukemia-60 Human Blood Myeloblast ECACC Cellosaurus HT-1080 Human Fibrosarcoma ECACC Cellosaurus HT-29 Human Colon epithelium Adenocarcinoma ECACC Cellosaurus
Cell_culture
Family of RNA-binding proteins
a FUS gene fused to one of the latter genes. Sclerosing epithelioid fibrosarcoma: The neoplastic cells in these tumors express the EWSR1-CREB3L1 fusion
FET_protein_family
Hormone produced by tumors
(Parathyroid hormone-related protein), TGF-α, TNF, IL-1 Hypoglycemia Fibrosarcoma Hemangiopericytomas Ectopic Insulin-like growth factor 2 Hyperaldosteronism
Ectopic_hormone
Blister-like protrusion filled with serous fluid
Ponuwei, Godwin A.; Dash, Phil R. (2016-12-01). "Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is Positively Regulated by the Lipid Signalling
Bleb_(medicine)
Medical condition
mutations in the transcription factor MafB, or V-maf musculoaponeurotic fibrosarcoma oncogene homolog B (MAFB), gene. This gene encodes a basic leucine zipper
Multicentric carpotarsal osteolysis syndrome
Multicentric_carpotarsal_osteolysis_syndrome
Tumor of the membranes surrounding the brain and spinal cord (meninges)
"epithelioma", "psammoma", "dural sarcoma", "dural endothelioma", "fibrosarcoma", "angioendothelioma", "arachnoidal fibroboastoma", "endotheliosis of
Meningioma
later awarded the Nobel prize in 1966. Chickens grow a tumor called a fibrosarcoma. Rous collected and ground up these sarcomas, and then centrifuged them
V-Src
Medical procedure that removes a part of the body
Cancerous bone or soft tissue tumors (e.g. osteosarcoma, chondrosarcoma, fibrosarcoma, epithelioid sarcoma, Ewing's sarcoma, synovial sarcoma, sacrococcygeal
Amputation
Pharmaceutical compound
the RAS-RAF-MAPK signaling pathway. It acts as a rapidly accelerated fibrosarcoma (RAF) kinase inhibitor. As of January 2025, flezurafenib has reached
Flezurafenib
Medical condition
tumor is an LPF-NT) and fibroma, infantile fibromatosis, congenital fibrosarcoma, solitary fibrous tumor, and dermatofibrosarcoma protuberans (broad expression
Lipofibromatosis-like neural tumor
Lipofibromatosis-like_neural_tumor
skin tumor with clinical and histological features dermatofiboma and fibrosarcoma 22 medijastinoskopija 18 endoscopic procedure of examination and biopsy
List of longest Croatian words
List_of_longest_Croatian_words
Hypoglycemia (low blood sugar) due to the presence of fibrous tumors
515–18. doi:10.1055/s-2000-11007. PMID 11149628. Doege, KW (1930). "Fibrosarcoma of the mediastinum". Ann Surg. 92 (5): 955–960. PMC 1398259. PMID 17866430
Doege–Potter_syndrome
Type of nasal cancer
malignant tumor of the nasal cavity, which was formerly probably included in fibrosarcoma and synovial sarcoma cases. It was incorporated into the fourth edition
Biphenotypic sinonasal sarcoma
Biphenotypic_sinonasal_sarcoma
Thickening of the feet's deep connective tissue (fascia)
the biopsy is predominantly cellular and frequently misdiagnosed as fibrosarcoma. Since the diseased area (lesion) is not encapsulated, clinical margins
Plantar_fibromatosis
Medical condition
tumors. A link to mesenchymal malignant tumors, such as osteosarcoma and fibrosarcoma, is exceedingly rare but has been reported. Locating the tumor can prove
Oncogenic_osteomalacia
List of immortalized cell lines overgrown by other, more aggressive cells
HuK°39 Virtual kidney HeLa cervical adenocarcinoma CVCL_8283 HuT Virtual fibrosarcoma-derived cell line 8387 HeLa cervical adenocarcinoma CVCL_M861 IM-9 multiple
List of contaminated cell lines
List_of_contaminated_cell_lines
Chemical compound
et al. (July 2010). "Zoledronic acid inhibits proliferation of human fibrosarcoma cells with induction of apoptosis, and shows combined effects with other
Zoledronic_acid
Diagnosis classification
M8813/0 Fascial fibroma M8813/3 Fascial fibrosarcoma M8814/3 Infantile fibrosarcoma Congenital fibrosarcoma M8815/0 Solitary fibrous tumor Localized
International Classification of Diseases for Oncology
International_Classification_of_Diseases_for_Oncology
Medical condition
there have been cases of its malignant transformation into ameloblastic fibrosarcoma and odontogenic sarcoma. Cahn LR and Blum T, believed in "maturation
Ameloblastic_fibro-odontoma
Gene that has the potential to cause cancer
Cancers Gene functions Growth factors, or mitogens c-Sis glioblastomas, fibrosarcomas, osteosarcomas, breast carcinomas, and melanomas induces cell proliferation
Oncogene
Medical condition
Pathol. 66 (4): 536–49. PMID 13582394. Garret R (1958). "Glioblastoma and fibrosarcoma of the brain with extracranial metastases". Cancer. 11 (5): 888–94. doi:10
Gliosarcoma
Phenomenon that results in unusual rearrangement of an chromosomes
predictor of relapse t(12;15)(p13;q25) Acute myeloid leukemia, congenital fibrosarcoma, secretory breast carcinoma, mammary analogue secretory carcinoma of
Chromosomal_translocation
American biotechnology company
human xenografts of renal cell carcinoma, prostate adenocarcinoma and fibrosarcoma. Antitumor effects of CBL0102 were shown in vitro in several human tumor
Statera_BioPharma
Fibromuscular dysplasia of arteries Fibromuscular dysplasia Fibromyalgia Fibrosarcoma Idiopathic pulmonary fibrosis Fibrosing mediastinitis Fibrosis Fibrous
List_of_diseases_(F)
Medical condition
fibrocartilaginous dysplasia of bone, desmoplastic fibroma, low-grade fibrosarcoma, chondromyxoid fibroma and low-grade chondrosarcoma. A full account of
Fibrocartilaginous mesenchymoma of bone
Fibrocartilaginous_mesenchymoma_of_bone
Protein-coding gene in the species Homo sapiens
genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice". Int. J. Cancer. 119
FAM107A
British oncologist
"Effect of Cyclin D1 Overexpression on Drug Sensitivity in a Human Fibrosarcoma Cell Line". Journal of the National Cancer Institute. 88 (18): 1269–1275
Daniel_Hochhauser
Implant used in animals
at one Tesla magnetic field strength. In 2011 a microchip-associated fibrosarcoma was reported found in the neck of a 9-year old, neutered-male cat. Histological
Microchip_implant_(animal)
Disease of deer
Game Commission. Retrieved 2019-08-06. Wadsworth, JR (March 1954). "Fibrosarcomas in a deer". Journal of the American Veterinary Medical Association.
Deer_cutaneous_fibroma
most common form in dogs is multicentric, involving the lymph nodes. Fibrosarcoma* is a malignant tumor that most commonly occurs in the mouth in dogs
List_of_dog_diseases
Medical condition
because they have areas that resemble and tend to behave like malignant fibrosarcomas or 2) as a distinctly different tumor than DFSP. DFSP-FS tumors are
Dermatofibrosarcoma protuberans, fibrosarcomatous
Dermatofibrosarcoma_protuberans,_fibrosarcomatous
Opacity in the eye's lens present at birth
homeodomain transcription factor 3 (PITX3), avian musculoaponeurotic fibrosarcoma (MAF), and heat shock transcription factor 4 (HSF4). All newborns should
Congenital_cataract
Chemical compound
epidermoid carcinoma cell line KB The cervical cancer cell line HeLa The fibrosarcoma cell line HT1080 The acute leukemia cell lines U937 and HL-60 The prostate
Cucurbitacin_E
Protein found in humans
DNAM-/- mice model that was more susceptible to formation of spontaneous fibrosarcoma. It was shown that NK cells can kill leukemia and neuroblastoma cells
CD226
Protein-coding gene in the species Homo sapiens
secretory carcinoma of the parotid and other salivary glands, congenital fibrosarcoma, congenital mesoblastic nephroma, inflammatory myofibroblastic tumor
ETV6
Species of virus
of gammaretrovirus that infects primates. First isolation was from a fibrosarcoma in a woolly monkey (Lagothrix lagothrica). For its reproduction the virus
Woolly_monkey_sarcoma_virus
Protein-coding gene in the species Homo sapiens
ovarian, bladder and head and neck cancers) and sarcomas (chondrosarcoma, fibrosarcoma, liposarcoma, rhabdomyosarcoma and synovial sarcoma) and there is compelling
TBX3
Surgery performed on non-human animals
tumors, melanomas, squamous cell carcinomas, basal cell carcinomas, fibrosarcomas, and histiocytomas. Skin tumors are removed through either simple excisions
Veterinary_surgery
Subspecialty of surgical pathology
L. (2020-01-01). ""Hey! Whatever happened to hemangiopericytoma and fibrosarcoma?" An update on selected conceptual advances in soft tissue pathology
Soft_tissue_pathology
British physician
PMC 1988459. PMID 14904120. Johnson, A. G.; Stokes, J. F. (1964). "Fibrosarcoma of the Heart Diagnosed During Life". British Medical Journal. 1 (5381):
John_Fisher_Stokes
Immuno-Oncology researcher
gp96, as a tumor rejection antigen from several chemically induced fibrosarcoma models. Major contribution to gp96/GRP94 biology: Li defined the ATPase
Zihai_Li
Researcher
and replaced it with a marker protein DNA which killed breast cancer, fibrosarcoma, and cervical cancer cells with minimal effect on normal cells. Following
Vera_Gorbunova
Glycoprotein, a homologue of a hormone stanniocalcin
2000). "Stanniocalcin 1 and 2 are secreted as phosphoproteins from human fibrosarcoma cells". The Biochemical Journal. 350 Pt 2 (2): 453–61. doi:10.1042/0264-6021:3500453
STC1
Bulge in the plasma membrane of a cell
15347/wjm/2017.008. Ponuwei GA, Dash PR (2016-12-01). "Bleb Formation in Human Fibrosarcoma HT1080 Cancer Cell Line Is Positively Regulated by the Lipid Signalling
Bleb_(cell_biology)
Medical condition
motion Redness or warmth Skin changes (ulceration, discoloration) (b) Fibrosarcomas, peripheral nerve sheath tumors and other fibrous neoplasms (c) Kaposi
Childhood_cancer
Protein-coding gene in humans
Fibrosarcoma cells, reportedly stained with an antibody binding to CD151 (green) and a dye for the nucleus (blue).
CD151
Type of programmed cell death distinct from apoptosis and necrosis
thioxotriazole copper (II) complex, also caused paraptosis in HT1080 fibrosarcoma cells via endoplasmic reticulum stress and cytoplasmic vacuolization
Paraptosis
Tumor originating in adipose (fat) tissue
expressed by the neoplastic cells in >95% or <5%, respectively, of myxoid fibrosarcoma cases. Inactivation of the RB1 tumor suppressor gene due to its deletion
Liposarcoma
Informal grouping of viruses
P53. Cells expressing the ORF-1 gene have even been shown to produce fibrosarcomas when injected into mice. Another product of HHV-6, the immediate early
Human_herpesvirus_6
Threadworm infections of dogs are frequent
various malignant tumors. In addition to squamous cell carcinomas and fibrosarcomas, the esophageal cells can also degenerate into osteosarcomas. The tumor-induced
Nematode_infection_in_dogs
Medical condition
of the heart include rhabdomyosarcomas, angiosarcomas, myxosarcomas, fibrosarcomas, leiomyosarcomas, reticulum cell sarcomas, desmoplastic small round
Primary_tumors_of_the_heart
System of biological structures
to UV rays. Additionally, a cancer of the connective tissue, known as fibrosarcoma, is often seen in the leg or wing. This occurs in many parrot species
Avian_immune_system
diagnosed either through their physical appearance or a biopsy testing. Fibrosarcomas arise from the fibrous tissues just beneath the skin. They may be present
Cancer_in_cats
Mammalian protein found in Homo sapiens
lines, so this gene was given the name Virus-induced Rapidly Accelerated Fibrosarcoma (V-RAF). A year later, another transforming gene was found in the avian
C-Raf
German bacteriologist (1852–1915)
bacteria into the tumors. His first patient, a 58-year-old woman with a fibrosarcoma of the gluteus, showed significant remission in the very large tumor
Friedrich_Fehleisen
Medical condition
Hardcastle syndrome Other names Bone dysplasia-medullary fibrosarcoma syndrome, diaphyseal medullary stenosis-malignant fibrous histiocytoma syndrome Hardcastle
Hardcastle_syndrome
Lutembacher believed the cysts and nodules to be metastases from a renal fibrosarcoma. This complication, which only affects women, is now known as lymphangioleiomyomatosis
Timeline of tuberous sclerosis
Timeline_of_tuberous_sclerosis
identified. Liposarcoma-like and chondroid foci can be an additional finding. Fibrosarcoma-like and fibrous histiocytoma-like areas can be observed as well as neurofibromatous
Ectomesenchymoma
for type 1 regulatory cells differentiation are: musculoaponeurotic fibrosarcoma(c-Maf) the aryl hydrocarbon receptor (AhR) interferon regulatory factor
Type_1_regulatory_T_cell
Artificial stimulation of the immune system to treat cancer
tumors, osteosarcoma, rhabdomyosarcoma, Ewing's sarcoma, liposarcoma, fibrosarcoma, leiomyosarcoma and other soft tissue sarcomas. It is not usually expressed
Cancer_immunotherapy
Mammalian protein found in Homo sapiens
protein 1 (PDX1), Neurogenin-3 (NEUROG3), and V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) are required for beta cell growth and differentiation
Neurogenin-3
Diagnostic technique
molecular imaging. This in-vivo imaging technique allowed diagnosis of fibrosarcoma in a rat model. Microbubbles and nanobubbles can also have different
Focused ultrasound-mediated diagnostics
Focused_ultrasound-mediated_diagnostics
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