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ESMODAFINIL

• Esmodafinil

Unmarketed enantiomer of modafinil

Esmodafinil (also known as (S)-modafinil or (+)-modafinil; developmental code name CRL-40983) is the enantiopure (S)-(+)-enantiomer of modafinil. Unlike

Esmodafinil



Esmodafinil

• Armodafinil

Wakefulness-promoting medication

almost identical to those of modafinil, a mixture of armodafinil and esmodafinil ((S)-(+)-modafinil). The (R)- and (S)-enantiomers have similar pharmacological

Armodafinil



Armodafinil

• Modafinil

Wakefulness-promoting medication

armodafinil and esmodafinil, have substantially different pharmacokinetics due to differing elimination profiles. Both armodafinil and esmodafinil are eliminated

Modafinil



Modafinil

• Methamphetamine

Central nervous system stimulant

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Methamphetamine



Methamphetamine

• Fladrafinil

Wakefulness-promoting drug

Analogues of fladrafinil include modafinil, armodafinil ((R)-modafinil), esmodafinil ((S)-modafinil), adrafinil (CRL-40,028; N-hydroxymodafinil), flmodafinil

Fladrafinil



Fladrafinil

• Eugeroic

Drug for wakefulness and alertness

Alertec, Modavigil, CRL-40476) – a racemic mixture of armodafinil and esmodafinil Solriamfetol (Sunosi). Pitolisant (Wakix). Adrafinil (Olmifon, CRL-40028

Eugeroic



Eugeroic

• Caffeine

Central nervous system stimulant

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Caffeine



Caffeine

• Adderall

Drug mixture used mainly to treat ADHD and narcolepsy

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Adderall



Adderall

• Dextroamphetamine

CNS stimulant and isomer of amphetamine

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Dextroamphetamine



Dextroamphetamine

• Methylphenidate

Central nervous system stimulant

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Methylphenidate



Methylphenidate

• Bupropion

Medication mainly used for depression and smoking cessation

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Bupropion



Bupropion

• Flmodafinil

Wakefulness-promoting drug/Dopamine reuptake inhibitor

Analogues of flmodafinil include modafinil, armodafinil ((R)-modafinil), esmodafinil ((S)-modafinil), adrafinil (CRL-40,028; N-hydroxymodafinil), fladrafinil

Flmodafinil



Flmodafinil

• Atomoxetine

Medication used to treat ADHD

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Atomoxetine



Atomoxetine

• Stimulant

Drug that increases alertness

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Stimulant



Stimulant

• Amphetamine

Central nervous system stimulant

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Amphetamine



Amphetamine

• Lisdexamfetamine

Central nervous system stimulant prodrug

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Lisdexamfetamine



Lisdexamfetamine

• Oveporexton

Pharmaceutical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Oveporexton



Oveporexton

• Pseudoephedrine

Synthetic decongestant

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Pseudoephedrine



Pseudoephedrine

• Γ-Hydroxybutyric acid

Chemical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Γ-Hydroxybutyric acid



Γ-Hydroxybutyric_acid

• Paraxanthine

Chemical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Paraxanthine



Paraxanthine

• List of modafinil analogues and derivatives

Armodafinil (Nuvigil, CRL-40982, CEP-10952, (R)-modafinil) – atypical DRI Esmodafinil (CRL-40983, (S)-modafinil) – atypical DRI Modafinil acid (modafinilic

List of modafinil analogues and derivatives



List_of_modafinil_analogues_and_derivatives

• Ephedrine

Medication, stimulant and decongestant

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Ephedrine



Ephedrine

• Xywav

Combination drug

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Xywav

Xywav

• Viloxazine

Medication used to treat ADHD and depression

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Viloxazine



Viloxazine

• Norepinephrine reuptake inhibitor

Medications that increase norepinephrine

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Norepinephrine reuptake inhibitor



Norepinephrine_reuptake_inhibitor

• Wakefulness-promoting agent

Drug that increases wakefulness

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Wakefulness-promoting agent



Wakefulness-promoting_agent

• Dopamine reuptake inhibitor

Class of drug

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Dopamine reuptake inhibitor

Dopamine_reuptake_inhibitor

• Nomifensine

Withdrawn antidepressant medication

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Nomifensine



Nomifensine

• Norepinephrine–dopamine reuptake inhibitor

Drug that inhibits the reuptake of norepinephrine and dopamine

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Norepinephrine–dopamine reuptake inhibitor



Norepinephrine–dopamine_reuptake_inhibitor

• Cleminorexton

Pharmaceutical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Cleminorexton



Cleminorexton

• Solriamfetol

Medication used for the treatment of excessive sleepiness

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Solriamfetol



Solriamfetol

• Pitolisant

Medication to treat narcolepsy

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Pitolisant



Pitolisant

• Balumorexton

Pharmaceutical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Balumorexton



Balumorexton

• Alixorexton

Novel chemistry compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Alixorexton



Alixorexton

• Danavorexton

Chemical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Danavorexton



Danavorexton

• Sodium oxybate

Medication to treat symptoms of narcolepsy

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Sodium oxybate



Sodium_oxybate

• Levoamphetamine

CNS stimulant and isomer of amphetamine

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Levoamphetamine



Levoamphetamine

• Firazorexton

Chemical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Firazorexton



Firazorexton

• Mazindol

Appetite suppressant

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Mazindol



Mazindol

• C15H15NO2S

Index of chemical compounds with the same molecular formula

mass: 273.35 g/mol, exact mass: 273.0823 u) may refer to: Armodafinil Esmodafinil Modafinil This set index page lists chemical structure articles associated

C15H15NO2S

C15H15NO2S

• List of investigational narcolepsy and hypersomnia drugs

Investigational narcolepsy and hypersomnia drugs

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

List of investigational narcolepsy and hypersomnia drugs

List_of_investigational_narcolepsy_and_hypersomnia_drugs

• Reboxetine

NRI antidepressant drug

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Reboxetine



Reboxetine

• Ledasorexton

Pharmaceutical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Ledasorexton



Ledasorexton

• Serdexmethylphenidate

CNS stimulant prodrug

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Serdexmethylphenidate



Serdexmethylphenidate

• H3 receptor antagonist

Antihistaminic drug

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

H3 receptor antagonist

H3_receptor_antagonist

• Samelisant

Experimental drug to treat narcolepsy

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Samelisant

Samelisant

• Istradefylline

Chemical compound

Catecholaminergic agents Dopamine reuptake inhibitors (DRIs): Adrafinil‡ Armodafinil Esmodafinil Mesocarb‡ Modafinil Phenylpiracetam (fonturacetam) Norepinephrine reuptake

Istradefylline



Istradefylline

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ESMODAFINIL

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ESMODAFINIL

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