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Brain surgery to treat epilepsy
Epilepsy surgery involves a neurosurgical procedure where an area of the brain involved in seizures is either resected, ablated, disconnected or stimulated
Epilepsy_surgery
Chronic focal seizure disorder
Anticonvulsant medications, epilepsy surgery, and dietary treatments may improve seizure control. Under the International League Against Epilepsy (ILAE) 2017 classification
Temporal_lobe_epilepsy
Group of neurological disorders causing seizures
drugs, other approaches, such as surgery, neurostimulation or dietary changes, may be considered. Not all cases of epilepsy are lifelong, and many people
Epilepsy
American medical scientist (born 1965)
physician and neurosurgeon. Schwartz specializes in surgery for brain tumors, pituitary tumors and epilepsy. He is particularly known for developing and expanding
Theodore_H._Schwartz
Scale for epilepsy surgery outcomes
classify postoperative outcomes for epilepsy surgery, Jerome Engel proposed the following scheme, the Engel Epilepsy Surgery Outcome Scale, which has become
Engel_classification
Cluster of signs and symptoms that define a unique epileptic condition
An epilepsy syndrome is defined as "a characteristic cluster of clinical and Electroencephalography (EEG) features, often supported by specific etiological
Epilepsy_syndromes
Type of electrophysiological monitoring
electrical stimulation during ECoG recordings in patients undergoing epilepsy surgery under local anesthesia. This procedure was used to explore the functional
Electrocorticography
Medical condition
temporal lobe epilepsy surgery have hippocampal sclerosis. About 7% of those with temporal lobe epilepsy have familial mesial temporal lobe epilepsy, and 57%
Hippocampal_sclerosis
Period of symptoms due to excessive or synchronous neuronal brain activity
by at least two anti-seizure medications, brain surgery can be a treatment option. Epilepsy surgery is especially useful for those with focal seizures
Seizure
American neurologist
staff physician in Cleveland Clinic's Epilepsy Center. Her research has focused on the role of epilepsy surgery in children with drug-resistant seizures
Elaine_Wyllie
Medical intervention
Drug-resistant epilepsy (DRE), also known as refractory epilepsy, intractable epilepsy, or pharmacoresistant epilepsy, refers to a state in which an individual
Management of drug-resistant epilepsy
Management_of_drug-resistant_epilepsy
Medical specialty of disorders which affect any portion of the nervous system
endarterectomy (CEA). Stereotactic neurosurgery, functional neurosurgery, and epilepsy surgery (the latter includes partial or total corpus callosotomy – severing
Neurosurgery
Form of epilepsy that may be related to a psychiatric problem or a sleep disorder
Frontal lobe epilepsy (FLE) is a neurological disorder that is characterized by brief, recurring seizures arising in the frontal lobes of the brain, that
Frontal_lobe_epilepsy
High-fat dietary therapy for epilepsy
epilepsy with the first drug they use, whereas around 30% do not achieve control with drugs. When drugs fail, other options include epilepsy surgery,
Ketogenic_diet
Surgical removal of one hemisphere of the brain
diseased hemisphere from the skull. This surgery is mostly used as a treatment for medically intractable epilepsy, which is the term used when anti-seizure
Hemispherectomy
for epilepsy include medications, diet, and surgery. Diet and surgery are considered for children who have medication resistant epilepsy. Epilepsy is classified
Epilepsy_in_children
Medical condition
stimulation but not epilepsy surgery. The ketogenic diet is a high fat, low carbohydrate diet reserved for intractable childhood epilepsies. There are no published
Ring_chromosome_20_syndrome
Japanese Canadian neurologist (1924–2023)
establishing cerebral dominance and is conducted worldwide prior to epilepsy surgery. Wada was a professor in the Department of Psychiatry and Neurosciences
Juhn_Atsushi_Wada
Medical treatment that involves delivering electrical impulses to the vagus nerve
medications and that the patient is ineligible for epilepsy surgery. This is because epilepsy surgery is associated with a higher probability of resulting
Vagus_nerve_stimulation
Panamanian-American neurologist
of neurology at Northwell Health, specializing in the field of epilepsy, epilepsy surgery and neuro-imaging. He was one of the first to recognize and prove
Ruben_Kuzniecky
Failure of certain neurons to migrate during brain development
Dong-Wook (December 30, 2013). "Focal cortical dysplasia and epilepsy surgery". Journal of Epilepsy Research. 3 (2): 43–47. doi:10.14581/jer.13009. ISSN 2233-6249
Focal_cortical_dysplasia
Medical condition
Musicogenic epilepsy is a form of reflex epilepsy with seizures elicited by special stimuli. It was probably described for the first time in 1605 by the
Musicogenic_epilepsy
Sexual stimulation of one's own genitals
Emin; Ozkara, Cigdem (2004). "Excessive masturbation after epilepsy surgery". Epilepsy & Behavior. 5 (1): 133–136. doi:10.1016/j.yebeh.2003.10.009.
Masturbation
Neurological test of the brain hemispheres
patient to the other. The test is usually performed prior to ablative surgery for epilepsy and sometimes prior to tumor resection. The aim is to determine which
Wada_test
Heightened sense of empathy
patient who became hyper-empathic after receiving resective epilepsy surgery, a form of brain surgery. The patient's behavioral modification remained unchanged
Hyper-empathy
Medical condition featuring permanent bending of fingers
thyroid problems, liver disease, diabetes, previous hand trauma, and epilepsy. Genetic studies have implicated mutations in the Wnt signaling pathway
Dupuytren's_contracture
Hospital in Kuopio, Finland
curve recordings and epilepsy surgery, which are nationwide concentrated in Kuopio and Helsinki, but most of Finland's epilepsy surgical procedures are
Kuopio_University_Hospital
Neurosurgery performed while the patient is awake
glioblastomas, gliomas, and brain metastases. It can also be used for epilepsy surgery to remove a larger amount of the section of tissue causing the seizures
Awake_craniotomy
Surgical procedure for epilepsy
treat epilepsy, van Wagenen studied and published the results of his surgeries, including the split-brain outcomes for patients. Most of the surgeries involved
Corpus_callosotomy
Mapping brain activity by recording magnetic fields produced by currents in the brain
epilepsy, and in localizing eloquent cortex for surgical planning in patients with brain tumors or intractable epilepsy. The goal of epilepsy surgery
Magnetoencephalography
Rare form of childhood-onset epilepsy
Lennox–Gastaut syndrome (LGS) is a complex, rare, and severe childhood-onset epilepsy syndrome. It is characterized by multiple and concurrent seizure types
Lennox–Gastaut_syndrome
Indian neurologist (born 1948)
Thiruvananthapuram, India. He has contributed for the resurgence of epilepsy surgery in India during 1990s, after the decline in 1970s. He also served as
Kurupath_Radhakrishnan
Hospital in Mbale District, Uganda
Richard; Howard, Charles; Andermann, Frederick (May 2009). "Surgery for pharmacoresistant epilepsy in the developing world: A pilot study". Epilepsia. 50 (5):
CURE Children's Hospital of Uganda
CURE_Children's_Hospital_of_Uganda
Surgical operation on skull
which can be used for temporal lobe tumors, mesial temporal lobe epilepsy surgery, or other middle fossa pathology. Pterional: Approach to the Sylvian
Craniotomy
Parts of the cerebrum
verbal and nonverbal learning before and after temporal lobe epilepsy surgery". Epilepsy & Behavior. 66: 57–63. doi:10.1016/j.yebeh.2016.11.037. Berret
Lobes_of_the_brain
Type of generalized seizure that affects the entire brain
Tonic–clonic seizures are the seizure type most commonly associated with epilepsy and seizures in general and the most common seizure associated with metabolic
Generalized tonic–clonic seizure
Generalized_tonic–clonic_seizure
Medical condition
Post-traumatic epilepsy (PTE) is a form of acquired epilepsy that results from brain damage caused by physical trauma to the brain (traumatic brain injury
Post-traumatic_epilepsy
Area in visual space that can be seen when the eye fixates a point
of vision. Epilepsy: Although field defects are rarely associated with epilepsy, defects may occur after temporal lobe surgery for epilepsy. Periventricular
Visual_field
Physician specializing in epileptology
and Treatment of Epilepsy: A Practical Guide. Elsevier Science. ISBN 9780080529462. Lüders, H.; Comair, Y.G. (2001). Epilepsy Surgery. Lippincott Williams
Epileptologist
French neurophysiologist
Neurosciences des Systèmes. He is the coordinator of the "Improving Epilepsy surgery management and prognosis using Virtual brain technology" (EPINOV) project
Fabrice_Bartolomei
Academic neurosurgery department in Chicago, Illinois
neurosurgery Timothy F. Witham, spinal neurosurgery Youssef G. Comair, epilepsy surgery Pat M. Raksin, neurotrauma and cerebrovascular neurosurgery Arthur
University of Chicago Department of Neurological Surgery
University_of_Chicago_Department_of_Neurological_Surgery
condition epilepsy. Following from that, there is a short list of people who have received a speculative, retrospective diagnosis of epilepsy. Finally
List_of_people_with_epilepsy
Electrophysiological method to record electrical activity of the brain
prognostic information. If a patient with epilepsy is being considered for resective surgery to treat epilepsy, it is often necessary to localize the focus
Electroencephalography
Canadian neurosurgeon (born 1956)
on pediatric neurosurgery, the molecular biology of brain tumours, epilepsy surgery, and surgical education. In 2014, he was appointed as the 7th Editor-in-Chief
James_Rutka
British physician
seizure onset in children with drug resistant focal epilepsy and has developed an epilepsy surgery programme based on her research. Cross conducted the
Helen_Cross_(physician)
Mood disorder
Events Caused by Anti-seizure Medications and Epilepsy Surgery?". Psychiatric and Behavioral Aspects of Epilepsy. Current Topics in Behavioral Neurosciences
Major_depressive_disorder
Medical condition
Sleep-related hypermotor epilepsy (SHE), previously known as nocturnal frontal lobe epilepsy, is a form of focal epilepsy characterized by seizures which
Sleep-related hypermotor epilepsy
Sleep-related_hypermotor_epilepsy
Human neurological disorder
(2003). The amygdala and sexual drive: insights from temporal lobe epilepsy surgery. Annals of neurology, 55(1), 87-96. Baird, A.D., Wilson, S.J., Bladin
Witzelsucht
Hospital in British Columbia, Canada
and inpatient surgical cases per year Respiratory Medicine and Thoracic Surgery Alzheimer Clinic BC Injury Prevention Centre Centre for Cardiac Rehabilitation
Vancouver_General_Hospital
Set of techniques to measure and visualize aspects of the nervous system
regions. This information can help plan for epilepsy surgery as a treatment for drug resistant epilepsy. Other radiotracers have also been used to identify
Neuroimaging
Type of brain surgery
temporal lobe epilepsy – An overview of surgical techniques". International Journal of Surgery. Epilepsy surgery for pharmacoresistant epilepsy. 36 (Pt B):
Anterior_temporal_lobectomy
Class of medications
has shown good results in patients whose epilepsy has not responded to medications and who cannot receive surgery. The vagus nerve stimulator is a device
Anticonvulsant
Indian neurosurgeon
S. T. Narasimhan. He was the first surgeon in India to perform an epilepsy surgery on 25 August 1952, on a patient suffering from right infantile hemiplegia
Jacob_Chandy
Medical condition
symptoms and day-to-day living. For cases related to focal brain lesions, epilepsy surgery or functional hemispherectomy may be considered. Risk factors include
Ohtahara_syndrome
Stroke prior to or soon after birth
MedicalNewsToday. 20 October 2017. Mandybur, George (July 2018). "Epilepsy surgery". Mayfield Clinic. Jayalakshmi, Sita; Panigrahi, Manas; Kulkarni, DilipKumar;
Perinatal_stroke
Speech difficulty associated with aphasia
presurgically so that critical areas can be saved when performing tumor or epilepsy surgery. Ganser syndrome Language disorder Lists of language disorders Malapropism
Paraphasia
asystole: A rare cardiac manifestation of temporal lobe epilepsy, treated with epilepsy surgery". Annals of Indian Academy of Neurology. 20 (1): 55–57
Ictal_asystole
Research and Development Institute in India
in India, like Epilepsy surgery and Deep Brain Stimulation. In the past 15 years, the institute has done nearly 1,220 epilepsy surgeries – the highest
Sree Chitra Tirunal Institute for Medical Sciences and Technology
Sree_Chitra_Tirunal_Institute_for_Medical_Sciences_and_Technology
German physicist and neuroscientist
trial EPINOV ("Improving epilepsy surgery management and prognosis using virtual brain technology") for drug-resistant epilepsy where Jirsa serves as scientific
Viktor_K._Jirsa
American actor (born 1966)
after Brain Surgery" By Lisa Ingrassia[link removed] April 1, 2009 Look To the Stars: "Greg Grunberg" retrieved November 2, 2013 Epilepsy Foundation:
Greg_Grunberg
Hospital in Eastern Region, Saudi Arabia
Neurosurgery: complex spine surgery, skull base surgery, vascular neurosurgery, epilepsy surgery, pediatric neurosurgery Neurology: epilepsy, multiple sclerosis
King Fahad Specialist Hospital Dammam
King_Fahad_Specialist_Hospital_Dammam
American neurosurgeon
fellowship training in two subspecialties: epilepsy surgery (at Yale University) and skull base/cerebrovascular surgery (at University of Arkansas Medical Sciences)
Aaron_Cohen-Gadol
American neurosurgeon
in epilepsy surgery at the University Hospital of Zürich in Switzerland. She further completed specialized fellowship training in epilepsy surgery, stereotactic
Isabelle_M._Germano
Altered state of consciousness after an epileptic seizure
using atypical antipsychotics and benzodiazepines, and successful epilepsy surgery can resolve the psychotic episodes. Postictal bliss or euphoria is
Postictal_state
Medical education
surgery Skull base surgery Pediatric neurosurgery Endoscopic & minimally invasive surgery Epilepsy surgery Functional and movement disorder surgery Neuro
Medical_education_in_India
Neurological Scientists of India
who together have been credited to be pioneers in development of epilepsy surgery in India. The society appointed Jacob Chandy as its first President
Neurological_Society_of_India
Hospital in Jharkhand, India
[dead link] "Steel city gets its first epilepsy clinic". indiatimes.com. "Newborn baby undergoes 'Life Saving' surgery at Brahmananda". avenuemail.in. "Specialists
Brahmananda Narayana Multispeciality Hospital, Jamshedpur
Brahmananda_Narayana_Multispeciality_Hospital,_Jamshedpur
Neurosurgical treatment
have since extended to include obsessive–compulsive disorder, refractory epilepsy, chronic pain, Tourette syndrome, and cluster headache. In the past three
Deep_brain_stimulation
Medical condition
underlying genetic cause. For example, epilepsy surgery in tuberous sclerosis complex or vestibular schwannoma surgery in neurofibromatosis type 2. However
Phakomatosis
together they have been credited to be pioneers in development of epilepsy surgery in India. They also helped in establishing the Neurological Society
S._T._Narasimhan
Hospital in Missouri, United States
3T MRI, DTI, PET, MEG, WADA, and ECoG) when evaluating patients for epilepsy surgery. The hospital has an imaging center named after sports announcer Joe
St._Louis_Children's_Hospital
Indian neurologist (1904–1998)
together they have been credited to be pioneers in development of epilepsy surgery in India. They also helped in establishing the Neurological Society
Baldev_Singh_(neurologist)
Outcome type in clinical trials
Instrument, National Eye Institute Visual Functioning Questionnaire, Epilepsy Surgery Inventory, Migraine Specific Quality of Life (MSQOL), the Ankylosing
Patient-reported_outcome
Canadian pediatric neurosurgeon
endoscopic hemispherectomy for patients with epilepsy. Lam is the Vice Chair for Pediatric Neurological Surgery at Northwestern University and the Division
Sandi_Lam
Surgical treatment modality for epilepsy
brain may mildly impair the language function served by that area. Epilepsy surgery is reserved for people whose seizures are not well controlled by seizure
Multiple_subpial_transection
Tool for analyzing neuroimaging scans
goal of ictal SPECT is to localize the region of seizure onset for epilepsy surgery planning. ISAS was introduced and validated in two recent studies (Chang
Ictal-Interictal SPECT Analysis by SPM
Ictal-Interictal_SPECT_Analysis_by_SPM
Genetic malformation syndrome
seizures is found in many different places in the brain, however, epilepsy surgery is rarely an option in Aicardi syndrome. Treatment with a ketogenic
Aicardi_syndrome
Involuntary, irregular muscle twitch
forms of essential myoclonus may be a type of epilepsy with no known cause. Juvenile myoclonic epilepsy (JME) usually consists of jerking and muscle twitches
Myoclonus
1972 novel by Michael Crichton
scientist in his mid-30s, is described as suffering from "psychomotor epilepsy" following a car crash two years earlier. He often has seizures followed
The_Terminal_Man
British mathematician
seizures and susceptibility to epilepsy, utilising mathematical models for the first time in the context of diagnosis and surgery. He is also highly cited in
John_R._Terry
Medical College of Georgia (30 January 2010). Neuropsychology of Epilepsy and Epilepsy Surgery. Oxford University Press. pp. 147–. ISBN 978-0-19-970699-0.
Interictal_dysphoric_disorder
Children's hospital and NHS Foundation trust in West Derby, Liverpool, England
Department of Health Centre for Head and Face Surgery One of four national centres for childhood epilepsy surgery, a joint service with the Royal Manchester
Alder_Hey_Children's_Hospital
Infrequent seizure precursor
Vertiginous epilepsy is infrequently the first symptom of a seizure, characterized by a feeling of vertigo. When it occurs, there is a sensation of rotation
Vertiginous_epilepsy
Robotic surgical assistant
2011) André Olivier, Warren W. Boling, Taner Tanriverdi, Techniques in Epilepsy Surgery: The MNI Approach, Cambridge University Press; 1 edition (March 26
ROSA
Postgraduate medical degree
cardiology, Epilepsy, stroke, electroencephalography, movement disorders, neuromuscular disorders, cerebrovascular surgery, skull base surgery, neurocritical
Doctor_of_Medicine
Epilepsy can affect employment for a variety of reasons. Many employers are reluctant to hire a person they know has epilepsy, even if the seizures are
Epilepsy_and_employment
Movement disorders that appear in early childhood
learning, feeling, communication and behavior often co-occur, with 28% having epilepsy, 58% having difficulties with communication, at least 42% having problems
Cerebral_palsy
applied to whole-brain connectome to determine seizure control after epilepsy surgery. Epilepsia, 59(9), 1643–1654. https://doi.org/10.1111/epi.14528 Neuroimaging
Leonardo_Bonilha
German neurologist and neurosurgeon
hyperventilation test for epilepsy, Foerster's syndrome, the first electrocorticogram of a brain tumor, and the first surgeries for epilepsy. He also made influential
Otfrid_Foerster
neurosurgeon studying novel uses of neuroendoscopy in minimally invasive epilepsy surgery Daphne Maurer (fl. from late 1980s), experimental psychologist focusing
List_of_women_neuroscientists
Anticonvulsant medication
antiallodynic properties. Its use in epilepsy is as an add-on therapy for partial seizures. When used before surgery, it reduces pain but results in greater
Pregabalin
Surgically drilling a hole in the skull
diagnosed with epilepsy, scurvy, frontal sinustis, intracranial disorders, diseases, hydrocephaly, and osteitis. In modern eye surgery, a trephine instrument
Trepanning
Benzodiazepine medication
childhood epilepsies, but it is ineffective in the control of infantile spasms. Clonazepam is mainly prescribed for the acute management of epilepsy. Clonazepam
Clonazepam
Medical procedure
disorders are: trigeminal neuralgia, Parkinson's disease, and epilepsy. Stereotactic surgery works on the basis of three main components:[citation needed]
Stereotactic_surgery
Condition of the human brain
seizures. Before using callosotomies, epilepsy is instead treated through pharmaceutical means. After surgery, neuropsychological assessments are often
Split-brain
Lebanese neurosurgeon and academic
Badajoz, pediatric neurosurgery at the Hôpital de la Timone [fr], epilepsy surgery at the Maudsley Hospital and neuronavigation at the Pitié-Salpêtrière
Youssef_Fares_(neurosurgeon)
Type of cortical scarring deep in the sulci
disability, cerebral palsy, and epilepsy. It has been observed that patients with polymicrogyria are not receptive to epilepsy surgery. However, responses of patients
Ulegyria
Flemish Renaissance painter (c.1500–c.1566)
Science & Business Media, 18 Feb 2014, p. 3 Hans O. Luders, Textbook of Epilepsy Surgery, CRC Press, 11 Jul 2008, p. 7 The Surgeon Archived 2 April 2015 at
Jan_Sanders_van_Hemessen
Medical condition
managed with surgery and medication. Surgery is used to treat cryptorchidism and cleft palate, whereas medication is used to treat epilepsy that may result
Börjeson–Forssman–Lehmann syndrome
Börjeson–Forssman–Lehmann_syndrome
Canadian neurosurgeon
in the early 1990s, where he held leadership roles in epilepsy surgery and skull base surgery. He later served as Professor and Chair of Neurosurgery
William_Couldwell
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