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Chemical compound
Eoxin E4 (EXE4), also known as 14,15-leukotriene E4, is an eoxin. Cells make eoxins by metabolizing arachidonic acid with a 15-lipoxygenase enzyme to
Eoxin_E4
Family of proinflammatory eicosanoids
15(S)-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (i.e. 15(S)-HpETE): Eoxin A4 Eoxin C4 Eoxin D4 Eoxin E4 A 15-lipoxygenase (i.e. ALOX15 or ALOX15B) metabolizes arachidonic
Eoxin
Index of chemical compounds with the same molecular formula
C23H37NO5S (molar mass: 439.61 g/mol) may refer to: Eoxin E4, or 14,15-leukotriene E4 Leukotriene E4, or LTE4 This set index page lists chemical structure
C23H37NO5S
Lipoxygenase found in humans
of inflammation responses and insulin secretion. Eoxins (e.g. eoxin C4, 14,15-eoxin D4, and eoxin E4) which have pro-inflammatory actions and contribute
ALOX15
Chemical compound
its 14,15-epoxide derivative, eoxin A4, and further metabolized to eoxin C4, eoxin D4, and eoxin E4 (there is no eoxin B4). Degraded non-enzymatically
15-Hydroxyeicosatetraenoic acid
15-Hydroxyeicosatetraenoic_acid
Class of compounds
the prostaglandins, thromboxanes, leukotrienes, lipoxins, resolvins, and eoxins. For each subfamily, there is the potential to have at least 4 separate
Eicosanoid
20-Carbon polyunsaturated fatty acid
and lipoxins; 15-Lipoxygenase-1 may also further metabolize 15-HPETE to eoxins in a pathway analogous to (and presumably using the same enzymes as used
Arachidonic_acid
Chronic inflammatory disease affecting the sinuses and lungs
activity and preferential conversion of arachidonic acid into 15-Oxo-ETE and eoxins over lipoxins contributes to inflammation in AERD. Various innate immune
Aspirin-exacerbated respiratory disease
Aspirin-exacerbated_respiratory_disease
Class of inflammation mediator molecules
particular. In excess, the cysteinyl leukotrienes can induce anaphylactic shock. Eoxins (14,15-leukotrienes) Wittig reaction § Example Loick, H.; Theissen, J. (1994)
Leukotriene
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