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CYCLIN A1

  • Cyclin A1
  • Protein-coding gene in the species Homo sapiens

    Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose

    Cyclin A1

    Cyclin A1

    Cyclin_A1

  • Cyclin A2
  • Protein-coding gene in the species Homo sapiens

    Cyclin-A2 is a protein that in humans is encoded by the CCNA2 gene. It is one of the two types of cyclin A: cyclin A1 is expressed during meiosis and

    Cyclin A2

    Cyclin A2

    Cyclin_A2

  • Cyclin-dependent kinase 2
  • Protein found in humans

    Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein

    Cyclin-dependent kinase 2

    Cyclin-dependent kinase 2

    Cyclin-dependent_kinase_2

  • Cyclin A
  • Protein family

    form. Cyclin A1 is prevalently expressed during meiosis and early on in embryogenesis. Cyclin A2 is expressed in dividing somatic cells. Cyclin A, along

    Cyclin A

    Cyclin_A

  • Inhibitor of CDK, cyclin A1 interacting protein 1
  • Protein-coding gene in the species Homo sapiens

    Inhibitor of CDK, cyclin A1 interacting protein 1 is a protein that in humans is encoded by the INCA1 gene. GRCh38: Ensembl release 89: ENSG00000196388

    Inhibitor of CDK, cyclin A1 interacting protein 1

    Inhibitor of CDK, cyclin A1 interacting protein 1

    Inhibitor_of_CDK,_cyclin_A1_interacting_protein_1

  • Cyclin-Y
  • Protein-coding gene in humans

    Cyclin-Y is a protein that in humans is encoded by the CCNY gene. GRCh38: Ensembl release 89: ENSG00000108100 – Ensembl, May 2017 GRCm38: Ensembl release

    Cyclin-Y

    Cyclin-Y

    Cyclin-Y

  • List of A1 genes, proteins or receptors
  • beta A1 Cyclic nucleotide-gated channel alpha 1 Cyclin A1 Cytochrome P450, family 1, member A1 Defensin, alpha 1 Dystrophin-associated protein A1 Ephrin

    List of A1 genes, proteins or receptors

    List_of_A1_genes,_proteins_or_receptors

  • P16
  • Mammalian protein found in humans

    p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that

    P16

    P16

    P16

  • Receptor for activated C kinase 1
  • Protein-coding gene in the species Homo sapiens

    has been shown to interact with: AGTRAP Androgen receptor, CD18, CD29 Cyclin A1 EIF6, FYN, IFNAR2, Janus kinase 1 OTUB1, P73, PDE4D, PRKCB1, PRKCE, PTPRM

    Receptor for activated C kinase 1

    Receptor for activated C kinase 1

    Receptor_for_activated_C_kinase_1

  • Chromosome 17
  • Human chromosome

    inducible domain family member 1B INCA1: encoding protein Inhibitor of cdk, cyclin a1 interacting protein 1 JPT1: encoding protein Jupiter microtubule associated

    Chromosome 17

    Chromosome 17

    Chromosome_17

  • Retinoblastoma protein
  • Mammalian protein found in humans

    ARID4A Aryl hydrocarbon receptor BRCA1 BRF1 C-jun C-Raf CDK9 CUTL1 Cyclin A1 Cyclin D1 Cyclin T2 DNMT1 E2F1 E2F2, E4F1 EID1 ENC1 FRK HBP1 HDAC1 HDAC3 Histone

    Retinoblastoma protein

    Retinoblastoma protein

    Retinoblastoma_protein

  • Maternal to zygotic transition
  • Stage in embryonic development

    Specifically, miR-427 targets include cell cycle regulators such as Cyclin A1 and Cyclin B2. Lee MT, Bonneau AR, Takacs CM, Bazzini AA, DiVito KR, Fleming

    Maternal to zygotic transition

    Maternal_to_zygotic_transition

  • Cyclin B3
  • Cell cycle protein

    G2/mitotic-specific cyclin-B3 is a protein encoded by the CCNB3 gene located on the X chromosome in humans. Cyclin B3 has features of both A type cyclins and B type

    Cyclin B3

    Cyclin B3

    Cyclin_B3

  • RBM4
  • Protein-coding gene in the species Homo sapiens

    engages in interactions with cyclin A1 and undergoes phosphorylation by cyclin A1–CDK2. The levels of RBM4 and cyclin A1 exhibit a correlation in normal

    RBM4

    RBM4

    RBM4

  • MYBL2
  • Protein-coding gene in the species Homo sapiens

    MYBL2 has been shown to interact with: CDK9 CREB-binding protein Cyclin A1 Cyclin-dependent kinase inhibitor 1C EP300 PARP1 Retinoblastoma-like protein

    MYBL2

    MYBL2

    MYBL2

  • Cell cycle hypothesis of Alzheimer's disease
  • by the absence of cyclin E1 and/or the inhibition of the cyclin-E1–CDK2 complex by p21, p27, and p53. Next, the absence of cyclin A1 commits the neuron

    Cell cycle hypothesis of Alzheimer's disease

    Cell_cycle_hypothesis_of_Alzheimer's_disease

  • GPS2 (gene)
  • Protein-coding gene in the species Homo sapiens

    protein 1) function. GPS2 (gene) has been shown to interact with: C21orf7, Cyclin A1, EP300, HDAC3, NCOR1, P53, and TBL1X. GRCh38: Ensembl release 89: ENSG00000132522

    GPS2 (gene)

    GPS2 (gene)

    GPS2_(gene)

  • Dragana Rogulja
  • Serbian neuroscientist

    the molecular mechanisms of sleep. Rogulja found that cyclin A (CycA) and its regulator cyclin A1 promote sleep in Drosophila. Fascinatingly, CycA is only

    Dragana Rogulja

    Dragana_Rogulja

  • Cytoglobin
  • Mammalian protein found in Homo sapiens

    (February 2006). "Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing"

    Cytoglobin

    Cytoglobin

    Cytoglobin

  • CDC20
  • Protein-coding gene in humans

    below). CDC20 has been shown to interact with: ANAPC7 BUB1B, CDC16, CDC27, Cyclin A1, FBXO5, HDAC1, HDAC2, and MAD2L1. However, the most important interaction

    CDC20

    CDC20

    CDC20

  • E2F1
  • Protein-coding gene in the species Homo sapiens

    promoter[PAX8] => E2F1 E2F1 has been shown to interact with: ARID3A, CUL1, Cyclin A1, Cyclin A2, GTF2H1, MDM4, NCOA6, NDN, NPDC1, PURA, PHB, RB1, UDG, RBL1, SKP2

    E2F1

    E2F1

    E2F1

  • P-TEFb
  • Protein complex regulating transcription in eukaryotes

    Drosophila cells. It is a cyclin dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T in Drosophila. In humans

    P-TEFb

    P-TEFb

    P-TEFb

  • Retinoblastoma-like protein 2
  • Protein-coding gene in the species Homo sapiens

    Retinoblastoma-like protein 2 has been shown to interact with: BRCA1, BRF1 C-Raf, Cyclin E1, Cyclin-dependent kinase 2, HDAC1, Prohibitin, and RBBP8. Mutations in RBL2

    Retinoblastoma-like protein 2

    Retinoblastoma-like protein 2

    Retinoblastoma-like_protein_2

  • OCEL1
  • Protein-coding gene in the species Homo sapiens

    Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1". Cancer Research. 68 (12): 4559–4570. doi:10.1158/0008-5472.can-08-0021

    OCEL1

    OCEL1

    OCEL1

  • Cyclin-dependent kinase 6
  • Protein found in humans

    encoded by the CDK6 gene. It is regulated by cyclins, more specifically by cyclin D proteins and cyclin-dependent kinase inhibitor proteins. The protein

    Cyclin-dependent kinase 6

    Cyclin-dependent kinase 6

    Cyclin-dependent_kinase_6

  • ARID2
  • Protein-coding gene in humans

    2004). "Identification of interaction partners and substrates of the cyclin A1-CDK2 complex". The Journal of Biological Chemistry. 279 (32): 33727–41

    ARID2

    ARID2

    ARID2

  • Cyclin E2
  • Protein

    Cyclin E2 is a protein that in humans is encoded by the CCNE2 gene. It is a G1 cyclin that binds Cdk2 and is inhibited by p27(Kip1) and p21(Cip1). It

    Cyclin E2

    Cyclin E2

    Cyclin_E2

  • Homeobox protein SIX1
  • Protein-coding gene in humans

    2004). "The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1". Proceedings of the National Academy of Sciences of the United States

    Homeobox protein SIX1

    Homeobox protein SIX1

    Homeobox_protein_SIX1

  • Cell division
  • Biological process

    controlled by cyclin and cyclin-dependent kinases. The progression of interphase is the result of the increased amount of cyclin. As the amount of cyclin increases

    Cell division

    Cell division

    Cell_division

  • 7SK RNA
  • Small nuclear RNA found in metazoans

    P-TEFb was a component of the complex. 7SK associates with and inhibits the cyclin dependent kinase activity of P-TEFb through the action of the RNA binding

    7SK RNA

    7SK RNA

    7SK_RNA

  • Meiosis
  • Cell division producing haploid gametes

    WEE1 as well as regulation of cyclin B levels facilitated by the anaphase-promoting complex (APC). CDK1 is regulated by cyclin B, whose synthesis peaks at

    Meiosis

    Meiosis

    Meiosis

  • TGF beta receptor 2
  • Protein-coding gene in the species Homo sapiens

    has been shown to interact with: AP2B1, Cyclin B2, Endoglin, Heat shock protein 90kDa alpha (cytosolic), member A1 STRAP, TGF beta receptor 1, and Transforming

    TGF beta receptor 2

    TGF beta receptor 2

    TGF_beta_receptor_2

  • Transcription factor II H
  • Protein complex

    the core complex. The remaining three subunits—CDK7, MAT1, and cyclin H—form the cyclin-activating kinase (CAK) subcomplex, which is tethered to the core

    Transcription factor II H

    Transcription_factor_II_H

  • D2
  • Topics referred to by the same term

    D2 Prostaglandin D2 receptor, a G-protein coupled receptor Resolvin D2 Cyclin D2 (CCND2) Vitamin D2, or ergocalciferol D02, the ICD-10 code for carcinoma

    D2

    D2

  • MyoD
  • Mammalian protein found in Homo sapiens

    repression of the D1 cyclin. Both MyoD and pRb are necessary for the repression of cyclin D1, but rather than acting directly on cyclin D1, they act on Fra-1

    MyoD

    MyoD

    MyoD

  • E2F
  • Family of transcription factors

    The phosphorylation of pRB is initiated by cyclin D/cdk4, cdk6 complex and continued by cyclin E/cdk2. Cyclin D/cdk4,6 itself is activated by the MAPK signaling

    E2F

    E2F

  • S100A4
  • Protein-coding gene in the species Homo sapiens

    invasion from proteins that contribute to metastasis, such as cathepsin B and cyclin B1. Together, these factors form polyploid giant cancer cells (PGCCs), which

    S100A4

    S100A4

    S100A4

  • MyoD family inhibitor domain containing
  • Protein-coding gene in the species Homo sapiens

    function transcription factor binding Tat protein binding protein binding cyclin binding Cellular component nucleolus nucleus cytoplasm Golgi apparatus nucleoplasm

    MyoD family inhibitor domain containing

    MyoD family inhibitor domain containing

    MyoD_family_inhibitor_domain_containing

  • Titin
  • Largest known protein in human muscles

    2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent kinase (EC 2.7.11.22) CDK1 CDK2 CDKL2 CDK3 CDK4 CDK5 CDKL5 CDK6

    Titin

    Titin

    Titin

  • DDX3X
  • Protein-coding gene in humans

    cell cycle progression through Cyclin E1. More specifically, DDX3X was shown to directly bind to the 5´ UTR of Cyclin E1, thereby facilitating the protein's

    DDX3X

    DDX3X

    DDX3X

  • GTPBP4
  • Protein-coding gene in the species Homo sapiens

    perinuclear region of cytoplasm nucleus cytosol Biological process regulation of cyclin-dependent protein serine/threonine kinase activity ribosome biogenesis negative

    GTPBP4

    GTPBP4

    GTPBP4

  • P53
  • Mammalian protein found in humans

    including CDKN1A, which encodes p21. Upon activation by p53, p21 inhibits cyclin-dependent kinases, leading to cell cycle arrest and contributing to tumor

    P53

    P53

    P53

  • Monoclonal B-cell lymphocytosis
  • Medical condition

    CD5+ in most cases, CD10−, CD23−, CD43+, CD103−, complete Ig+, and express cyclin D1; these cells have translocations between chromosomes 11 and 14 in >95%

    Monoclonal B-cell lymphocytosis

    Monoclonal_B-cell_lymphocytosis

  • Human papillomavirus infection
  • Human disease

    p53 also upregulates the p21 protein, which blocks the formation of the cyclin D/Cdk4 complex, thereby preventing the phosphorylation of retinoblastoma

    Human papillomavirus infection

    Human papillomavirus infection

    Human_papillomavirus_infection

  • Replication protein A2
  • Protein-coding gene in the species Homo sapiens

    gene. RPA2 has been shown to interact with: Cyclin O, DNA-PKcs, Ku70, MEN1, RPA3, Replication protein A1, STAT3, TP53BP1 and Uracil-DNA glycosylase. Single-stranded

    Replication protein A2

    Replication protein A2

    Replication_protein_A2

  • Calcium signaling
  • Intracellular communication process

    triggers Cdc25, a phosphatase that removes inhibitory phosphate groups from Cyclin-dependent Kinase 1 (Cdk1). This results in the activation of Cdk1, triggering

    Calcium signaling

    Calcium signaling

    Calcium_signaling

  • Androgen receptor
  • Mammalian protein found in humans

    C-jun, Calmodulin 1, Caveolin 1, CDK9, COX5B, CREB-binding protein, Cyclin D1, Cyclin-dependent kinase 7, DACH1, Death associated protein 6, L-DOPA, EFCAB6

    Androgen receptor

    Androgen receptor

    Androgen_receptor

  • DMTF1
  • Protein-coding gene in the species Homo sapiens

    Cyclin-D-binding Myb-like transcription factor 1 is a protein that in humans is encoded by the DMTF1 gene. GRCh38: Ensembl release 89: ENSG00000135164

    DMTF1

    DMTF1

    DMTF1

  • SFRS5
  • Protein-coding gene in the species Homo sapiens

    Müller-Newen G, Becker W (February 2004). "Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A

    SFRS5

    SFRS5

    SFRS5

  • SH3GLB1
  • Protein-coding gene in the species Homo sapiens

    Nairn AC, De Camilli P (January 2004). "Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses". Proceedings of the National Academy of

    SH3GLB1

    SH3GLB1

    SH3GLB1

  • PFTK1
  • Protein-coding gene in the species Homo sapiens

    Qin Y, et al. (2007). "Functional characterization of human PFTK1 as a cyclin-dependent kinase". Proc. Natl. Acad. Sci. U.S.A. 104 (22): 9248–53. Bibcode:2007PNAS

    PFTK1

    PFTK1

    PFTK1

  • Ubiquitin ligase
  • Protein

    key players in cell cycle control, mediating the degradation of cyclins, as well as cyclin dependent kinase inhibitor proteins. The human genome encodes

    Ubiquitin ligase

    Ubiquitin ligase

    Ubiquitin_ligase

  • CABLES1
  • Protein-coding gene in humans

    is a protein that in humans is encoded by the CABLES1 gene. CABLES1 is a cyclin-dependent kinase (CDK)-binding protein that plays a role in proliferation

    CABLES1

    CABLES1

    CABLES1

  • LATS1
  • Protein-coding gene in the species Homo sapiens

    histone H1 kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal

    LATS1

    LATS1

    LATS1

  • SKP2
  • Protein-coding gene in the species Homo sapiens

    stable complex with the cyclin A-CDK2 S-phase kinase. It specifically recognizes and promotes the degradation of phosphorylated cyclin-dependent kinase inhibitor

    SKP2

    SKP2

    SKP2

  • CDC34
  • Protein-coding gene in humans

    the cell cycle. Cdc34 in yeast targets numerous substrates - notably the cyclin-dependent kinase inhibitor Sic1 - for ubiquitin-mediated protein degradation

    CDC34

    CDC34

    CDC34

  • Synapsin I
  • Protein-coding gene in the species Homo sapiens

    kinases including those activated by cAMP, calcium/calmodulin, mitogen, and cyclin. Both isoforms have the same six phosphorylation sites: The N-terminal globular

    Synapsin I

    Synapsin I

    Synapsin_I

  • Heterogeneous ribonucleoprotein particle
  • Macromolecular complex containing protein and RNA molecules

    amount of an oncogenic variant Δ16HER2. HER2 is an upstream regulator of cyclin D1 and p27, and its overexpression leads to the deregulation of the G1/S

    Heterogeneous ribonucleoprotein particle

    Heterogeneous ribonucleoprotein particle

    Heterogeneous_ribonucleoprotein_particle

  • Forkhead box protein O1
  • Protein

    arrest is linked with cyclin D1 and cyclin D2 suppression in mammals. It was detected that human FOXO1 is linked with the cyclin D1 promoter using chromatin

    Forkhead box protein O1

    Forkhead box protein O1

    Forkhead_box_protein_O1

  • Schumanniophyton problematicum
  • Species of plant

    rohitukine and rohitukine N-oxide, and the iridoid glycosides scyphiphorin A1–A2 and scyphiphorin B1–B2. Alvocidib is a synthetic analog of rohitukine that

    Schumanniophyton problematicum

    Schumanniophyton problematicum

    Schumanniophyton_problematicum

  • ATF1
  • Protein-coding gene in humans

    calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation

    ATF1

    ATF1

    ATF1

  • PROX1
  • Protein-coding gene in the species Homo sapiens

    proliferation lens morphogenesis in camera-type eye positive regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of

    PROX1

    PROX1

    PROX1

  • SFRS7
  • Protein-coding gene in the species Homo sapiens

    Wang C, Yu Y, Yuan L, Zhang M, Cao X (Mar 2004). "Cyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis

    SFRS7

    SFRS7

    SFRS7

  • Ubiquitin
  • Regulatory protein found in most eukaryotic tissues

    degradation. SKP2 targets p27Kip-1, an inhibitor of cyclin-dependent kinases (CDKs). CDKs2/4 partner with the cyclins E/D, respectively, forming a family of cell

    Ubiquitin

    Ubiquitin

    Ubiquitin

  • Flap structure-specific endonuclease 1
  • Protein-coding gene in the species Homo sapiens

    Koundrioukoff S, Hübscher U (July 2003). "Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulation". Oncogene

    Flap structure-specific endonuclease 1

    Flap structure-specific endonuclease 1

    Flap_structure-specific_endonuclease_1

  • Steroidogenic factor 1
  • Protein-coding gene in humans

    modification. Specifically, phosphorylation of serine 203 is mediated by cyclin-dependent kinase 7. Mutations to CDK7 prevent interaction with the basal

    Steroidogenic factor 1

    Steroidogenic factor 1

    Steroidogenic_factor_1

  • Amphiphysin
  • Protein-coding gene in the species Homo sapiens

    Ochoa GC, Tsai LH, De Camilli P (March 2001). "Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by

    Amphiphysin

    Amphiphysin

    Amphiphysin

  • HER2
  • Mammalian protein found in humans

    Pruefer F, Bast RC (January 2005). "HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27Kip1 via multiple signaling pathways". Cell

    HER2

    HER2

    HER2

  • RUNX2
  • Protein-coding gene in humans

    protein phosphorylation. Furthermore, Runx2 controls the gene expression of cyclin D2, D3, and the CDK inhibitor p21(cip1) in hematopoietic cells. It has been

    RUNX2

    RUNX2

    RUNX2

  • MCM2
  • Protein-coding gene in humans

    (2000). "Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2". J. Biol. Chem. 275 (21): 16235–41. doi:10.1074/jbc.M909040199.

    MCM2

    MCM2

    MCM2

  • MCM6
  • (2000). "Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2". J. Biol. Chem. 275 (21): 16235–41. doi:10.1074/jbc.M909040199.

    MCM6

    MCM6

    MCM6

  • Mating of yeast
  • Biological process of yeast

    4307. PMC 2856190. PMID 20409458. Bhaduri S, Pryciak PM (October 2011). "Cyclin-specific docking motifs promote phosphorylation of yeast signaling proteins

    Mating of yeast

    Mating of yeast

    Mating_of_yeast

  • NEUROD1
  • Protein-coding gene in the species Homo sapiens

    of the cortex. Neurod1 has been shown to interact with MAP3K10, MAFA and Cyclin D1. GRCh38: Ensembl release 89: ENSG00000162992 – Ensembl, May 2017 GRCm38:

    NEUROD1

    NEUROD1

    NEUROD1

  • MCM4
  • Protein-coding gene in humans

    (2000). "Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2". J. Biol. Chem. 275 (21): 16235–41. doi:10.1074/jbc.M909040199.

    MCM4

    MCM4

    MCM4

  • Neratinib
  • Chemical compound

    BT474 cells, neratinib reduces HER2 autophosphorylation, and inhibited cyclin D1 expression while reduced proliferation has been observed A431 cells when

    Neratinib

    Neratinib

    Neratinib

  • Erythropoietin receptor
  • Protein-coding gene in the species Homo sapiens

    (for example, rate of division and corresponding changes in the levels of cyclins and Cdk inhibitors) in vivo awaits further work. In other cell systems

    Erythropoietin receptor

    Erythropoietin receptor

    Erythropoietin_receptor

  • AP-1 transcription factor
  • Instance of defined set in Homo sapiens with Reactome ID (R-HSA-6806560)

    (August 2001). "Dominant negative c-jun inhibits activation of the cyclin D1 and cyclin E kinase complexes". Molecular Biology of the Cell. 12 (8): 2352–63

    AP-1 transcription factor

    AP-1 transcription factor

    AP-1_transcription_factor

  • Von Hippel–Lindau tumor suppressor
  • Mammalian protein found in humans

    interacts with cyclin D1. This leads to increased survival due to lower rates of apoptosis and increased proliferation due to the activation of cyclin D1. Recent

    Von Hippel–Lindau tumor suppressor

    Von Hippel–Lindau tumor suppressor

    Von_Hippel–Lindau_tumor_suppressor

  • ELAV-like protein 1
  • Protein found in humans

    with degradation of the transcript. Phosphorylation of HuR can occur by cyclin-dependent kinases (cdks), impacting its localization within the cell in

    ELAV-like protein 1

    ELAV-like protein 1

    ELAV-like_protein_1

  • Transcription factor Jun
  • Mammalian protein found in Homo sapiens

    results in activated c-jun and its downstream targets such as RACK1 and cyclin D1. RACK1 can enhance JNK activity, and activated JNK signaling subsequently

    Transcription factor Jun

    Transcription factor Jun

    Transcription_factor_Jun

  • NRF1
  • Protein-coding gene in the species Homo sapiens

    isoforms have been described but they have not been fully characterized. Cyclin D1-dependent kinase, through phosphorylating NRF-1 at S47, coordinates nuclear

    NRF1

    NRF1

    NRF1

  • Encorafenib
  • Chemical compound

    kinase inhibitor, decreasing ERK phosphorylation and down-regulation of CyclinD1. This arrests the cell cycle in G1 phase, inducing senescence without

    Encorafenib

    Encorafenib

    Encorafenib

  • Marginal zone lymphoma
  • Group of lymphomas

    CD20, CD27, and BCL2 but not CD10, CD23, CD5, CD43, CD38, BCL6, cyclin D1, or annexin A1 marker proteins. These cells may also express the del7q deletion

    Marginal zone lymphoma

    Marginal zone lymphoma

    Marginal_zone_lymphoma

  • Dopamine receptor
  • Class of G protein-coupled receptors

    protein phosphatase 1. Sustained D1 receptor activity is kept in check by Cyclin-dependent kinase 5. Dopamine receptor activation of Ca2+/calmodulin-dependent

    Dopamine receptor

    Dopamine receptor

    Dopamine_receptor

  • List of MeSH codes (D12.776)
  • cerevisiae MeSH D12.776.167.200.067.875 – cyclin-dependent kinase 5 MeSH D12.776.167.200.067.900 – cyclin-dependent kinase 9 MeSH D12.776.167.200.580

    List of MeSH codes (D12.776)

    List_of_MeSH_codes_(D12.776)

  • CEBPA
  • Protein-coding gene in humans

    myeloid antecedents. CEBPA has been shown to interact with cyclin-dependent kinase 2 and cyclin-dependent kinase 4. It has been shown that mutation of CEBPA

    CEBPA

    CEBPA

    CEBPA

  • CFAP20DC
  • Human gene

    Pelliniemi LJ, Boesl M, Geley S (February 2012). "Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis". Molecular

    CFAP20DC

    CFAP20DC

    CFAP20DC

  • Retinoblastoma-like protein 1
  • Mammalian protein found in Homo sapiens

    Retinoblastoma-like protein 1 has been shown to interact with: BEGAIN, BRCA1, BRF1, Cyclin A2, Cyclin-dependent kinase 2, E2F1, HDAC1, MYBL2 Mothers against decapentaplegic

    Retinoblastoma-like protein 1

    Retinoblastoma-like protein 1

    Retinoblastoma-like_protein_1

  • Deubiquitinating enzyme
  • Protein family

    critical for the G1-S transition. For CDK2 to be activated, cyclin A must bind to the cyclin-dependent kinase complex (CDKC). Cell division cycle 25A (CDC25A)

    Deubiquitinating enzyme

    Deubiquitinating enzyme

    Deubiquitinating_enzyme

  • Vascular endothelial growth factor
  • Protein involved in blood vessel growth

    Ghada; Aboushady, Iman; Sabry, Dina (1 April 2019). "Decreased VEGF and Cyclin D1 Genes Expression Enhances Chemosensitivity of Human Squamous Cell Carcinoma

    Vascular endothelial growth factor

    Vascular_endothelial_growth_factor

  • GREB1
  • Protein-coding gene in the species Homo sapiens

    (2012). "The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in

    GREB1

    GREB1

    GREB1

  • MCM7
  • Protein-coding gene in humans

    possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and

    MCM7

    MCM7

    MCM7

  • GTF2H1
  • Protein-coding gene in the species Homo sapiens

    is encoded by the GTF2H1 gene. GTF2H1 has been shown to interact with: Cyclin-dependent kinase 7, E2F1, ERCC2, Estrogen receptor alpha, TCEA1, and XPB

    GTF2H1

    GTF2H1

    GTF2H1

  • UBE2C
  • Protein-coding gene in the species Homo sapiens

    Aristarkhov A, Beck S, Hershko A, Ruderman JV (Apr 1997). "Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase"

    UBE2C

    UBE2C

    UBE2C

  • Collapsin response mediator protein family
  • disease. Studies suggest that glycogen synthase kinase-3β (GSK-3β) and cyclin-dependent protein kinase 5 (Cdk5) are highly expressed in Alzheimer's disease

    Collapsin response mediator protein family

    Collapsin_response_mediator_protein_family

  • Baculoviral IAP repeat-containing protein 2
  • Protein-coding gene in the species Homo sapiens

    protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription". The Journal of Biological Chemistry. 286 (30): 26406–26417

    Baculoviral IAP repeat-containing protein 2

    Baculoviral IAP repeat-containing protein 2

    Baculoviral_IAP_repeat-containing_protein_2

  • Mir-223
  • RNA molecule

    that the RhoB mRNA is a bona fide miR-223 target. miR-223 also regulates cyclin E activity by modulating expression of the FBXW7 protein. In particular

    Mir-223

    Mir-223

    Mir-223

  • Transcription factor II B
  • Mammalian protein found in Homo sapiens

    TFIIB has to cyclin A. In order to undergo replication, viruses often stop host cell progression through the cell cycle, using cyclins and other proteins

    Transcription factor II B

    Transcription factor II B

    Transcription_factor_II_B

  • Mdm2
  • Protein-coding gene in humans

    Winckler S, Korgaonkar C, Tompkins V, Horne MC, Quelle DE (January 2003). "Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor

    Mdm2

    Mdm2

    Mdm2

  • Long non-coding RNA
  • Non-protein coding transcripts longer than 200 nucleotides

    acetyltransferase activities on a repressed gene target, cyclin D1. The recruitment of TLS to the promoter of cyclin D1 is directed by long ncRNAs expressed at low

    Long non-coding RNA

    Long non-coding RNA

    Long_non-coding_RNA

AI & ChatGPT searchs for online references containing CYCLIN A1

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CYCLIN A1

  • Catlin
  • Girl/Female

    Irish

    Catlin

    meaning pure.

    Catlin

  • Cailin
  • Girl/Female

    Irish Gaelic

    Cailin

    Girl.

    Cailin

  • Conlin
  • Boy/Male

    Gaelic Irish

    Conlin

    Hero.

    Conlin

  • Coilin
  • Boy/Male

    Gaelic Irish

    Coilin

    Virile.

    Coilin

  • COLLIN
  • Male

    English

    COLLIN

    Variant spelling of English Colin, COLLIN means "whelp; young pup."

    COLLIN

  • Cullin
  • Boy/Male

    Gaelic Irish

    Cullin

    Handsome; good-looking lad.

    Cullin

  • AYLIN
  • Female

    Turkish

    AYLIN

    Turkish name AYLIN means "moon halo."

    AYLIN

  • Cailin
  • Boy/Male

    Scottish

    Cailin

    Contemporary'Child.

    Cailin

  • Collin
  • Boy/Male

    Gaelic American Irish English French

    Collin

    child.

    Collin

  • Collin
  • Surname or Lastname

    English and French

    Collin

    English and French : from a pet form of English Coll 1, French Colle.Probably an altered spelling of German Kollin.Danish : variant of Colding.Swedish : ornamental name from an unexplained first element, probably from a place name, + the the suffix -in, from Latin -in(i)us ‘descendant of’.

    Collin

  • Carlin
  • Boy/Male

    Gaelic German Irish

    Carlin

    Small champion.

    Carlin

  • Collin
  • Boy/Male

    American, Australian, British, Celtic, Christian, Dutch, English, French, Gaelic, German, Greek, Irish, Portuguese

    Collin

    Creative; Victory of the People; Form of Colin; Victor; Abbreviation of Nicholas; Young Creature; People's Victory; Dove; One who had Travelled to Rome; Young Pup

    Collin

  • CAYLIN
  • Female

    English

    CAYLIN

    Variant spelling of English Kaylin, CAYLIN means "girl."

    CAYLIN

  • CARLIN
  • Female

    English

    CARLIN

    Irish Gaelic unisex name CARLIN means "little champion."

    CARLIN

  • Cocklin
  • Surname or Lastname

    English

    Cocklin

    English : from a diminutive of Middle English cok ‘cock’ (see Cocke).Perhaps also an Americanized spelling of Swiss and South German Köchlin, Koechlin, or Köchling, all diminutives of Koch.

    Cocklin

  • Bhawar
  • Boy/Male

    Indian, Sikh

    Bhawar

    Cyclone

    Bhawar

  • Catlin
  • Surname or Lastname

    English

    Catlin

    English : from the medieval female personal name Cat(e)lin(e), Anglo-Norman French form of Catherine.

    Catlin

  • Caylin
  • Girl/Female

    Gaelic

    Caylin

    Girl; lass.

    Caylin

  • Colin
  • Surname or Lastname

    French

    Colin

    French : from a reduced pet form of the personal name Nicolas (see Nicholas).English : variant spelling of Collin.A Colin from Brittany, France, is documented in St. Ours, Quebec, in 1669, with the secondary surname LaLiberté, which is often translated Liberty; Colin is often Americanized as Collins.

    Colin

  • Caplin
  • Surname or Lastname

    English

    Caplin

    English : occupational name for a chantry priest (or the servant of one), a priest endowed to sing mass daily on behalf of the souls of the dead (Late Latin capellanus). Compare Chaplin.Americanized spelling of Swiss German Kaeppelin, a diminutive of Kappel.

    Caplin

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CYCLIN A1

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