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CpG oligodeoxynucleotides (or CpG ODN) are short single-stranded synthetic DNA molecules that contain a cytosine triphosphate deoxynucleotide ("C") followed
CpG_oligodeoxynucleotide
Class of short biopolymers
forms because of mutations; can often be tested with ASO probes CpG Oligodeoxynucleotide, an ODN with immunostimulatory properties Polypurine reverse-Hoogsteen
Oligonucleotide
Topics referred to by the same term
regulation CpG island - regions of DNA that contain several CpG sites CpG oligodeoxynucleotide - unmethylated sequences of DNA that have immunostimulatory properties
CpG
Type of nanostructure
adaptive and innate—by delivering specific nucleotides, such as CpG oligodeoxynucleotide, to the body. They may be designed to have enhanced dispersity
Nanosphere
induced protection against Staphylococcus aureus infection or CpG oligodeoxynucleotide training protecting against infectious with Escherichia coli. Evidence
Trained_immunity
Class of immune system proteins
of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides". Journal of Immunology. 168 (9): 4531–7. doi:10.4049/jimmunol
Toll-like_receptor
previous vaccines, but includes a novel CpG 1018 adjuvant, a 22-mer phosphorothioate-linked oligodeoxynucleotide. It was non-inferior concerning immunogenicity
Phosphorothioate_nucleic_acid
Topics referred to by the same term
Newlyn, the mean sea-level height datum in Great Britain. CpG Oligodeoxynucleotide also known as a CpG ODN, a molecule with immunostimulatory properties. Open
ODN
Chemical compound
Agatolimod (also known as CpG 7909, ODN 2006, PF-3512676, VaxImmune, and ProMuneT) is a CpG Oligodeoxynucleotide which acts as a toll-like receptor 9 agonist
Agatolimod
Complementarity-determining region Computational immunology Contact immunity CpG Oligodeoxynucleotide CR6261 CroFab Cross-presentation Cross-reactivity Cryptic self
Index_of_immunology_articles
American pathology researcher (born 1948)
Virus Vaccine: Mucosal Delivery of Fusion Glycoprotein with a CpG Oligodeoxynucleotide Adjuvant". Journal of Virology (24): 13156. Maryna C. Eichelberger;
Gregory_Prince
Chemical synthesis of nucleic acids
M. P.; Thornton, A. H.; Sarin, P. S.; Zamecnik, P. C. (1988). "Oligodeoxynucleotide phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency
Oligonucleotide_synthesis
Protein found in humans
(EGFR) is constitutively bound to TLR9. It can be activated by CpG Oligodeoxynucleotides such as Agatolimod. GRCh38: Ensembl release 89: ENSG00000239732
Toll-like_receptor_9
Polish American cancer researcher and immunologist
siRNA with triggering of immune receptor, Toll-like receptor 9 (TLR9) using CpG motif DNA. Later on, he adopted the strategy as a platform for delivery of
Marcin_Kortylewski
Vaccine against hepatitis B
previous vaccines, but includes a novel CpG 1018 adjuvant, a 22-mer phosphorothioate-linked oligodeoxynucleotide. It was non-inferior concerning immunogenicity
Hepatitis_B_vaccine
Dutch chemist (1930–2023)
sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide." Proceedings of the National Academy of Sciences of the United States
Henk_Buck
Medications based on ribonucleic acids
1016/S0022-3565(24)36667-4. PMID 9152389. Farman CA, Kornbrust DJ (2016-11-17). "Oligodeoxynucleotide studies in primates: antisense and immune stimulatory indications"
RNA_therapeutics
BBBD – BBR 2778 – BBR 3464 – BCG – BCG solution – bcl-2 antisense oligodeoxynucleotide G3139 – BCX-1777 – Beckwith-Wiedemann syndrome – beclomethasone –
Index_of_oncology_articles
Type of DNA damage
cyclobutane thymine dimer produced in high yield by UVB light in an oligodeoxynucleotide at acidic pH". Journal of the American Chemical Society. 130 (34):
Pyrimidine_dimer
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE
CPG OLIGODEOXYNUCLEOTIDE