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Class of beta-lactam antibiotic
Cephems are a sub-group of β-lactam antibiotics including cephalosporins and cephamycins. It is one of the more common 4-membered ring Heterocyclic compounds
Cephem
Class of broad-spectrum antibiotics
includes penicillin derivatives (penams), cephalosporins and cephamycins (cephems), monobactams, carbapenems and carbacephems. Most β-lactam antibiotics
Β-Lactam_antibiotic
Class of pharmaceutical drugs
cephamycins, they constitute a subgroup of β-lactam antibiotics called cephems. Cephalosporins were discovered in 1945, and first sold in 1964. The aerobic
Cephalosporin
Beta-lactam antibiotic
Kidney Identifiers IUPAC name (7R)-3-methyl-7-(α-D-phenylglycylamino)-3-cephem-4-carboxylic acid monohydrate CAS Number 15686-71-2 Y PubChem CID 2666 IUPHAR/BPS
Cefalexin
structures. (A) A penam. (B) A carbapenam. (C) An oxapenam. (D) A penem. (E) A carbapenem. (F) A monobactam. (G) A cephem. (H) A carbacephem. (I) An oxacephem.
List_of_β-lactam_antibiotics
Synthetic antibiotic class
antibiotics, based on the structure of cephalosporin, a cephem. Carbacephems are similar to cephems, but with a carbon substituted for the sulfur. It prevents
Carbacephem
Chemical compound
alpha.-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-1-oxa-1-dethia-3-cephem-4-carboxylic acid disodium salt (6059-S) and its related 1-oxacephems".
Latamoxef
Group of β-lactam antibiotics
as cephalosporins. Like cephalosporins, cephamycins are based upon the cephem nucleus. Unlike most cephalosporins, cephamycins are a very efficient antibiotic
Cephamycin
Systematic naming of drugs
Penicillin-derived antibiotics penicillin, carbenicillin, oxacillin cef- Cephem-type antibiotics cefazolin, cephalexin -mab Monoclonal antibodies trastuzumab
Drug_nomenclature
Family of chemical compounds
reactive. Monobactams have h values between 0.05 and 0.10 angstroms (Å). Cephems have h values in of 0.20–0.25 Å. Penams have values in the range 0.40–0
Β-Lactam
Chemical compound
assigned to Fujisawa US 4427674, Takaya T, Hisashi T, Kiyoshi T, Toshiyuki C, "Cephem compounds", issued 24 January 1984, assigned to Fujisawa v t e
Ceftizoxime
Chemical compound
Beta lactam antibiotic, like penicillin. Its chemical structure contains cephems,carboxyl groups and a pyridinium ring. Cephaloridine is mainly used in
Cephaloridine
Chemical compound
Cefaparole (cephaparole) is a cephem antibiotic of the cephalosporin subclass that was never marketed. Yamada H, Jimpo K, Tobiki H, Komatsu T, Noguchi
Cefaparole
Genus of bacteria
Harada, S., S. Tsubotani, H. Ono, and H. Okazaki. 1984. Cephabacins, new cephem antibiotics of bacterial origin. II. Isolation and characterization. J Antibiot
Lysobacter
Species of bacterium
First-choice drugs for E. corrodens infections should be third-generation cephems, carbapenems, or new quinolones. It is innately resistant to macrolides
Eikenella_corrodens
Species of fungus
Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor". Metabolic Engineering. 11 (2): 125–137. doi:10.1016/j
Penicillium_rubens
Combination antibiotic medication
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Aztreonam/avibactam
Chemical compound
discovery of erythromycin, another antibiotic. Cephamycin C was the first cephem discovered but while it was highly resistant to several beta-lactamases
Cefoxitin
Chemical compound
Singh GS (January 2004). "Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and sulbactam". Mini Reviews in Medicinal Chemistry
Sulbactam
Chemical to treat skin infections
inhibitory action on bacterial cell wall synthesis. In addition to the cephem nucleus common to all cephalosporins, cefditoren has an aminothiazole group
Cefditoren
Class of pharmaceutical drugs
An oxacephem is a β-lactam molecule similar to a cephem, but with an oxygen substituted for the sulfur. They are synthetic compounds not seen in nature
Oxacephem
Antibiotic combination drug
Singh GS (January 2004). "Beta-lactams in the new millennium. Part-II: cephems, oxacephems, penams and sulbactam". Mini Reviews in Medicinal Chemistry
Cefoperazone/sulbactam
Chemical compound
has a bicyclic ring with four-member β-lactam ring fused to a six-member cephem ring. Ceftaroline is thought to have activity against MRSA with its 1,3-thiazole
Ceftaroline_fosamil
Agent which kills bacteria
beta-lactam antibiotics (penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems) and vancomycin. Also bactericidal are daptomycin
Bactericide
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Side_effects_of_penicillin
Antibiotic
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Benzathine_benzylpenicillin
Cephalosporin antibiotic
synthesized by reaction of 3-(1-methyl-1H-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (1) with trifluoromethylthioacetyl chloride (2). DeMarinis
Cefazaflur
Chemical compound
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Avibactam
Class of enzymes
lactamdurans encoding a 3'-methylcephem hydroxylase different from the 7-cephem hydroxylase". Appl. Microbiol. Biotechnol. 44 (5): 605–9. doi:10.1007/BF00172492
Deacetoxycephalosporin-C hydroxylase
Deacetoxycephalosporin-C_hydroxylase
Combination antibiotic drug
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Ampicillin/sulbactam
Chemical compound
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Epicillin
Chemical compound
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Cefozopran
Chemical compound
Biapenem‡ Panipenem) Penems (Faropenem Ritipenem§ Sulopenem Tebipenem pivoxil) Cephems Cephalosporins Cephamycins Carbacephems 1st generation Cefazolin# Cefalexin
Carumonam
Chemical used in the treatment of asthma
not be used in people with liver disease. Use with paracetamol or with cephem antibiotics increases the risk of liver damage. Use with aspirin increases
Seratrodast
Bactericidal antibiotics
(MRSA). Ceftobiprole is a pyrrolidinone-3-ylidenemethyl cephem. The C-3 side chain was specifically designed to have a strong binding affinity
Discovery and development of cephalosporins
Discovery_and_development_of_cephalosporins
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