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See searches and references containing CDK19!CDK19
Mammalian protein found in Homo sapiens
by the CDK19 gene. The natural product cortistatin A is a potent and selective inhibitor of CDK8 and CDK19. Romaciclib is a dual CDK8 and CDK19 inhibitor
CDK19
Investigational drug
treatment of acute myeloid leukaemia (AML). It is a dual inhibitor of CDK8 and CDK19. "Romaciclib - Ryvu Therapeutics". AdisInsight. Springer Nature Switzerland
Romaciclib
Chemical compound
CDK8 and CDK19, the kinases that associate with Mediator complex. Out of 386 kinases evaluated, cortistatin A only inhibited CDK8 and CDK19, revealing
Cortistatins
Protein domain
CDK11A ; CDK11B ; CDK12 ; CDK13 ; CDK14 ; CDK15 ; CDK16 ; CDK17 ; CDK18 ; CDK19 ; CDK2 ; CDK20 ; CDK3 ; CDK4 ; CDK5 ; CDK6 ; CDK7 ; CDK8 ; CDK9 ; CDKL1 ;
Protein_kinase_domain
Protein-coding gene in the species Homo sapiens
cortistatin A is a potent and selective inhibitor of CDK8 and CDK19. Inhibition of CDK8 and CDK19 with cortistatin A suppresses AML cell growth and has anticancer
Cyclin-dependent_kinase_8
Region of a genome which regulates expression of genes related to cell identity
phosphorylated and up-activated by particular cyclin-dependent kinases (Cdk8, Cdk9, Cdk19, etc.), will then promote higher levels of transcription. The regulation
Super-enhancer
HGNC:8749; Q00536 2662 CDK17 HGNC:8750; Q00537 2663 CDK18 HGNC:8751; Q07002 2664 CDK19 HGNC:19338; Q9BWU1 2665 CDK20 HGNC:21420; Q8IZL9 2666 CDKAL1 HGNC:21050;
List of human protein-coding genes 2
List_of_human_protein-coding_genes_2
CDK19
CDK19
CDK19
CDK19
CDK19
CDK19
CDK19
CDK19
CDK19