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CapZ, also known as CAPZ, CAZ1, CAPPA1 and beta-actinin, is a capping protein that caps the barbed end of actin filaments in muscle cells. CapZ is a heterodimeric
CapZ
Protein-coding gene in humans
CapZ is a heterodimer composed of an α and β subunit. In muscle, capping protein α1 subunit and β1 subunit are localized at the Z-disc, and form CapZ
CAPZB
Protein-coding gene in humans
protein subunit alpha-2 also known as CapZ-alpha2 is a protein that in humans is encoded by the CAPZA2 gene. CapZ-alpha2 is a 33.0 kDa protein composed
CAPZA2
Protein found in humans
properties of a Ca(2+)-independent barbed-end actin filament capping protein, CapZ, from human polymorphonuclear leukocytes". Biochemistry. 35 (11): 3518–24
Capping protein (actin filament) muscle Z-line, alpha 1
Capping_protein_(actin_filament)_muscle_Z-line,_alpha_1
Microscopic protrusion of a cell membrane that increases surface area substantially
filaments are located at the tip of the microvillus and are capped, possibly by capZ proteins, while the minus ends are anchored in the terminal web composed
Microvillus
Filament in the cytoplasm of eukaryotic cells
turnover is important for the cell's movement. End-capping proteins such as CapZ prevent the addition or loss of monomers at the filament end where actin
Actin_filament
Family of proteins that form microfilaments
stabilizing them. These are called "capping proteins" and include CapZ and tropomodulin. CapZ binds the (+) end of a filament, preventing further addition
Actin
Protein family
"Variant cDNAs encoding proteins similar to the alpha subunit of chicken CapZ". Cell Motil. Cytoskeleton. 18 (3): 204–14. doi:10.1002/cm.970180306. PMID 1711931
F-actin_capping_protein
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2025_Philippine_local_elections_in_Western_Visayas
American neurobiologist and pathologist
observation of actin filament severing by gelsolin and binding by gCap39 and CapZ". The Journal of Cell Biology. 115 (6): 1629–1638. doi:10.1083/jcb.115.6
Elaine_Bearer
Class of proteins
Calvasculin Ciboulot Coactosin CAP23 CARMIL Acan125 Cingulin Cytovillin (Ezrin) CapZ/Capping Protein a-Catenin Cofilin CR16 Caldesmon CCT Comitin Calicin Centuarin
Actin-binding_protein
Protein-coding gene in the species Homo sapiens
Cardioprotection in mice with reduction of CapZ showed enhancement in PKCε translocation to sarcomeres, thus suggesting that CapZ may compete with PKCε for the binding
PRKCE
Protein
of the actin fibre. This, along with plus end capping proteins, such as capZ stabilise the structure of the actin filament. End capping is particularly
Tropomodulin
Protein found in humans
junction formation in association with the filamentous actin-capping protein CapZ, by controlling actin-driven membrane remodeling. Paracingulin thus really
Cingulin-like_protein_1
Process of remodeling actin filaments
verification] Barbed-end uncapping by the removal of barbed-end-capping proteins (CapZ, Hsp70, EPS8) Barbed-end uncapping by actin-binding-proteins that sever actin
Actin_remodeling
Motor protein
DCTN2/p50/dynamitin, DCTN3/p24/p22;(2)the Arp1 filament: ACTR1A/Arp1/centractin, actin, CapZ; and (3) the pointed end complex: Actr10/Arp11, DCTN4/p62, DCTN5/p25, and
Dynactin
Protein-coding gene in the species Homo sapiens
2003). "Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85". The Journal of Biological Chemistry. 278 (25): 22396–403
SH3KBP1
Protein
(2003). "Linking the T cell surface protein CD2 to the actin-capping protein CAPZ via CMS and CIN85". J. Biol. Chem. 278 (25): 22396–403. doi:10.1074/jbc.M302540200
CD2AP
750.078.730.032 – actin capping proteins MeSH D05.750.078.730.032.500 – capz actin capping protein MeSH D05.750.078.730.032.750 – tropomodulin MeSH D05
List_of_MeSH_codes_(D05)
MeSH D12.776.210.500.910.962 – troponin t MeSH D12.776.220.525.032.500 – capz actin capping protein MeSH D12.776.220.525.032.750 – tropomodulin MeSH D12
List_of_MeSH_codes_(D12.776)
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