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Chemical compound
Abacavir (ABC), sold under the brand name Ziagen among others, is a medication used to treat HIV/AIDS. Similar to other nucleoside analog reverse-transcriptase
Abacavir
Mixture of chemical compounds
Abacavir/lamivudine/zidovudine, sold under the brand name Trizivir, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS
Abacavir/lamivudine/zidovudine
Abacavir/lamivudine/zidovudine
Combination medication for HIV
Abacavir/dolutegravir/lamivudine, sold under the brand name Triumeq among others, is a fixed-dose combination antiretroviral medication for the treatment
Abacavir/dolutegravir/lamivudine
Abacavir/dolutegravir/lamivudine
Chemical compound
combination with other antiretrovirals such as zidovudine, dolutegravir, and abacavir. Lamivudine may be included as part of post-exposure prevention in those
Lamivudine
Pharmaceutical company
markets 17 products: Nucleoside reverse transcriptase inhibitors (NRTIs): abacavir (brand name Ziagen) lamivudine (brand names Epivir and 3TC) zidovudine
ViiV_Healthcare
Combination drug for HIV
Abacavir/lamivudine (ABC/3TC), sold under the brand name Kivexa among others, is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS
Abacavir/lamivudine
Formulary by the World Health Organization
Dolutegravir Raltegravir Abacavir/dolutegravir/lamivudine (abacavir + dolutegravir + lamivudine) Abacavir/lamivudine (abacavir + lamivudine)
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
Antiretroviral medication
exposure. It is sold both by itself and together as lamivudine/zidovudine and abacavir/lamivudine/zidovudine. It can be used by mouth or by slow injection into
Zidovudine
Class of prescription drugs in India
Family Welfare. The most recent schedule H (2006) lists 536 drugs from abacavir to zuclopenthixol. However, enforcement of Schedule H laws in India is
Schedule_H
Chemical compound
drug acyclovir, often used in herpes treatment, and the anti-HIV drug abacavir, are structurally similar to guanosine. Guanosine was also used to make
Guanosine
competitive substrate inhibitors. Examples of NRTIs include zidovudine, abacavir, lamivudine, emtricitabine, and of NtRTIs – tenofovir and adefovir. Non-nucleoside
Management_of_HIV/AIDS
the FDA are zidovudine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine and the only nucleotide reverse-transcriptase inhibitor
Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors
Discovery_and_development_of_nucleoside_and_nucleotide_reverse-transcriptase_inhibitors
American scientist (born 1940)
termed 'carbovirs'. This class of medicinal agents included the drug abacavir. Abacavir was commercialized by GlaxoSmithKline as Ziagen for the treatment
Robert_Vince_(scientist)
Pharmaceutical drug classification
Didanosine J05AF03 Zalcitabine J05AF04 Stavudine J05AF05 Lamivudine J05AF06 Abacavir J05AF07 Tenofovir disoproxil J05AF08 Adefovir dipivoxil J05AF09 Emtricitabine
ATC_code_J05
Rare reaction to certain medications
pleuritis, or the acute respiratory distress syndrome; minocycline and abacavir are the main culprit drugs causing severe lung involvement. However, lung
Drug rash with eosinophilia and systemic symptoms
Drug_rash_with_eosinophilia_and_systemic_symptoms
Misuse of data analysis
a particular HIV treatment, abacavir, and lower-risk patients to other drugs, preventing a simple assessment of abacavir compared to other treatments
Data_dredging
Chemical compound
dolutegravir, such as dolutegravir/rilpivirine, dolutegravir/lamivudine, and abacavir/dolutegravir/lamivudine, are also available. As of 2019, the World Health
Dolutegravir
Public university in Minnesota, U.S.
termed 'carbovirs.' This class of medicinal agents included the drug abacavir. Abacavir was commercialized by GlaxoSmithKline as Ziagen for the treatment
University_of_Minnesota
Medical condition
selective COX-2 inhibitors (e.g. celecoxib) Antiviral Acyclovir, atazanavir, abacavir, indinavir Analgesic Aspirin, acetaminophen Gastrointestinal Proton pump
Interstitial_nephritis
Topics referred to by the same term
Association of Black Cardiologists, a North American nonprofit organization Abacavir, an antiretroviral drug used to treat HIV/AIDS ABC (medicine), a mnemonic
ABC
Antiretroviral vaginal ring
Elsulfavirine (ESV) Combined formulations Abacavir/lamivudine# Abacavir/dolutegravir/lamivudine° Abacavir/lamivudine/zidovudine Atazanavir/cobicistat
Dapivirine_Ring
Skin disease
Taiwan, Hong Kong, Thailand, and mainland China. Before treatment with abacavir, the USA Food and Drug Administration recommends screening for HLA-B*57:01
Stevens–Johnson_syndrome
Adverse reaction to HIV/AIDS treatment
to decrease the incidences of immune medicated adverse drug reactions. Abacavir is an HIV medication that can cause adverse reactions like hives and fevers
HIV disease–related drug reaction
HIV_disease–related_drug_reaction
Chemical compound
nucleosides. Vince's work with this lactam eventually led to his synthesis of abacavir. Peramivir synthesis is also dependent on Vince lactam starting material
Vince_lactam
Co-packaged antiretroviral medication
inhibitors (RTIs) Nucleoside and nucleotide (NRTI) Nucleoside analogues/NRTIs: Abacavir (ABC)# Didanosine (ddI)◊ Emtricitabine (FTC) Islatravir (ISL) Lamivudine
Cabotegravir/rilpivirine
Metabolic medical condition
glycol (D-lactic acidosis) Nucleoside reverse-transcriptase inhibitors Abacavir/dolutegravir/lamivudine Emtricitabine/tenofovir Potassium cyanide (cyanide
Lactic_acidosis
Laboratories No Trizivir abacavir lamivudine zidovudine November 15, 2000 ViiV Healthcare Yes Epzicom (US) Kivexa (EU, RU) abacavir lamivudine August 2, 2004
List of antiretroviral fixed-dose combinations
List_of_antiretroviral_fixed-dose_combinations
Human leukocyte antigen serotype
of the skin. Individuals with B57 are more sensitive to the drug abacavir. Abacavir is an antiretroviral drug used in treatment of HIV, however in sensitive
HLA-B57
Drug that causes an adverse reaction to alcohol
disulfiram-like reactions upon ingestion of alcohol as an unintended effect include: Abacavir Cephalosporins, but only these with a methylthiotetrazole side chain or
Disulfiram-like_drug
Inability to produce or maintain healthy fat tissue
J, Doong N, Martin A, Amin J, Freund J, Law M, Cooper DA (July 2002). "Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: a
Lipodystrophy
Class of antiretroviral drug
Epivir. It is approved for the treatment of both HIV and hepatitis B. Abacavir, also called ABC, has the trade name Ziagen, is an analog of guanosine
Reverse-transcriptase inhibitor
Reverse-transcriptase_inhibitor
American pharmaceutical and healthcare corporation
injection for the treatment of relapsing forms of multiple sclerosis. Abacavir/dolutegravir/lamivudine: In September 2023, received tentative US FDA approval
Viatris
Rash on the mucous membranes
Concia E (March 2003). "Enanthema as the first clinical manifestation of abacavir hypersensitivity reaction: a case report". Infez Med. 11 (1): 40–1. PMID 12719670
Enanthem
Means of delivering drugs to a cell
(May 2005). "Application of phosphoramidate pronucleotide technology to abacavir leads to a significant enhancement of antiviral potency". Journal of Medicinal
Protide
Brazil's federal drug control statute
Thalidomide Lenalidomide Pomalidomide List revoked in September 2016. Abacavir Amprenavir Atazanavir Darunavir Delavirdine Didanosine (ddI) Dolutegravir
Brazilian Controlled Drugs and Substances Act
Brazilian_Controlled_Drugs_and_Substances_Act
Experimental antibody for HIV treatment
Elsulfavirine (ESV) Combined formulations Abacavir/lamivudine# Abacavir/dolutegravir/lamivudine° Abacavir/lamivudine/zidovudine Atazanavir/cobicistat
Semzuvolimab
Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir HIV ViiV Healthcare Nucleoside analogue reverse transcriptase inhibitor
List_of_antiviral_drugs
Group of adverse drug reactions involving the skin and mucosa
the most commonly reported offenders being Carbamazepine, allopurinol, abacavir, phenytoin, and nevirapine. These drugs evoke SCARs by interacting with
Severe cutaneous adverse reactions
Severe_cutaneous_adverse_reactions
Antiviral medication used against herpes, chickenpox, and shingles
listing Schaeffer as inventor was issued in 1979. Vince later invented abacavir, an nRTI drug for HIV patients. Elion was awarded the 1988 Nobel Prize
Aciclovir
Overreaction of the immune system to an antigen
requirements. Days–weeks on first course; can be rapid; faster on re-exposure. Abacavir hypersensitivity (HLA-B57:01) carbamazepine SJS/TEN (HLA-B15:02 in many
Hypersensitivity
Skin rash resembling measles
reactions (in particular with certain classes of antiretroviral drugs, such as abacavir and nevirapine, and also the antiepileptic drug phenytoin), or other conditions
Morbilliform
Biochemical compound
virus zalcitabine (ddC) — HIV guanosine and deoxyguanosine analogues: abacavir (ABC) — HIV aciclovir — antiviral entecavir (ETV) — hepatitis B virus ganciclovir
Nucleoside_analogue
Excess number of eosinophil cells in the blood
desipramine, amitriptyline, fluoxetine, piroxicam, diclofenac, ACE inhibitors, abacavir, nevirapine, ranitidine, cyclosporin, and hydrochlorothiazide. The toxic
Eosinophilia
Werwein, Marianne; Schwingel, Eva; Korn, Klaus (2002). "Prediction of Abacavir Resistance from Genotypic Data: Impact of Zidovudine and Lamivudine Resistance
Adverse_event_prediction
Formulary
Dolutegravir Raltegravir Abacavir/dolutegravir/lamivudine (abacavir + dolutegravir + lamivudine) Abacavir/lamivudine (abacavir + lamivudine) Lamivudine/zidovudine
WHO Model List of Essential Medicines for Children
WHO_Model_List_of_Essential_Medicines_for_Children
Medical condition
particular drugs and ethnic populations. The most important of which is abacavir (an anti-viral used in the treatment of HIV) hypersensitivity associated
Drug_eruption
Class of chemical compounds
nucleosides, the anti-HIV agent abacavir and the anti-hepatitis B agent entecavir, are reverse-transcriptase inhibitors. Abacavir, was developed from racemic
Carbocyclic_nucleoside
A-Hydrocort A-Methapred A-N stannous aggregated albumin A-Poxide A.P.L. A/T/S abacavir (INN) abafungin (INN) abagovomab (INN) abamectin (INN) abanoquil (INN)
List_of_drugs:_A–Ab
Protein-coding gene in the species Homo sapiens
of hypersensitivity reactions to abacavir, a nucleoside reverse transcriptase inhibitor used to treat HIV. Abacavir hypersensitivity reactions often result
HLA-B
Chemical compound
fosamprenavir-ritonavir versus lopinavir-ritonavir, each in combination with abacavir-lamivudine, for initial treatment of HIV infection over 48 weeks: a randomised
Fosamprenavir
Anti-HIV combination medication
commercially available in the United States as of 2018. Lamivudine/zidovudine Abacavir/lamivudine/zidovudine "Nevirapine, zidovudine and lamivudine" (PDF). aidsmap
Lamivudine/nevirapine/zidovudine
Lamivudine/nevirapine/zidovudine
receptors on the surface but also inside the cell (endoplasmic reticulum e.g. Abacavir to HLA-B*57:01). This may cause a change of presented peptides (altered
P-i_mechanism
Chemical compound
combined with emtricitabine and tenofovir alafenamide versus dolutegravir, abacavir, and lamivudine for initial treatment of HIV-1 infection: week 96 results
Bictegravir
Medical condition
streptomycin, dapsone, nitrofurantoin, metronidazole, nevirapine, efavirenz, abacavir, nevirapine. Anticonvulsants/Antipsychotics/antidepressants: phenindione
Eosinophilic_myocarditis
American physician
fosamprenavir-ritonavir versus lopinavir-ritonavir, each in combination with abacavir-lamivudine, for initial treatment of HIV infection over 48 weeks: a randomized
Jeffrey_P._Nadler
Protein-coding gene in the species Homo sapiens
antiviral induced Fanconi syndrome. The use of stavudine, didenosine, abacavir, adefovir, cidofovir and tenofovir has been associated with Fanconi syndrome
Organic_anion_transporter_1
International organisation
granted 14 voluntary licences generics companies for low-cost versions of abacavir used to treat children living with HIV. As of 2018, the Medicines Patent
Medicines_Patent_Pool
Protein found in humans
protease inhibitor antiretroviral lamivudine Nucleoside analog antiviral abacavir Nucleoside analog antiretroviral emtricitabine Nucleoside analog antiviral
ATP-binding cassette sub-family C member 2
ATP-binding_cassette_sub-family_C_member_2
American filmmaker (born 1973)
Nevirapine, 3TC, and d4T. In 1998, she replaced d4T in her regimen with Abacavir because d4T caused severe side effects. Jako has permanent truncal adiposity
Jennifer_Jako
attaining reduced prices. For example, GSK added a secondary patent for abacavir (ABC) with only minor changes and was able to effectively extend its patent
Cost_of_HIV_treatment
Drug delivery method
has isoniazid-rifapentine (for the treatment of latent tuberculosis) and abacavir-lumevadine-dolutegravir (ALD, for the treatment of HIV/AIDS) oral dissolvable
Thin-film_drug_delivery
Drug delivery methodology
novel vaginal drug delivery system: anti-HIV bioadhesive film containing abacavir". Journal of Materials Science: Materials in Medicine. 25 (7): 1679–1689
Cervical_drug_delivery
include the following: Evidence of abacavir's diminished efficacy in HIV patients with high viral load Evidence of abacavir's association with increased risk
XVII International AIDS Conference, 2008
XVII_International_AIDS_Conference,_2008
inosine-5′-monophosphate dehydrogenase (IMPDH)-inhibitor. It enhances abacavir but reduces the effect of AZT and d4T. Works analogous to HU and RV only
Synergistic enhancer (antiretroviral)
Synergistic_enhancer_(antiretroviral)
Non-profit organization
the nucleoside reverse transcriptase inhibitors (NRTIs) lamivudine and abacavir for the treatment of paediatric HIV. The 4-in-1 is a significant improvement
Drugs for Neglected Diseases Initiative
Drugs_for_Neglected_Diseases_Initiative
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