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45 DIHYDROXYTRYPTAMINE

• Monoamine neurotoxin

Compounds that damage or destroy monoaminergic neurons

para-chloroamphetamine (PCA), methylenedioxymethamphetamine (MDMA), and 5,7-dihydroxytryptamine (5,7-DHT); the dopaminergic neurotoxins oxidopamine (6-hydroxydopamine)

Monoamine neurotoxin



Monoamine_neurotoxin

• Para-Bromomethamphetamine

Pharmaceutical compound

and Sebastian 2007). Orikasa S, Sloley BD (1988). "Effects of 5,7-dihydroxytryptamine and 6-hydroxydopamine on head-twitch response induced by serotonin

Para-Bromomethamphetamine



Para-Bromomethamphetamine

• 5-Methoxytryptamine

Chemical compound

(April 1978). "Effects of reserpine, para-chlorophenylalanine, 5,6-dihydroxytryptamine and fludiazepam on the head twitches induced by 5-hydroxytryptamine

5-Methoxytryptamine



5-Methoxytryptamine

• Oxidopamine

Chemical compound

brain, since it is not able to cross the blood brain barrier. 5,7-Dihydroxytryptamine 6-Hydroxydopa DSP-4 MPTP Norsalsolinol Rotenone FAUC50 Simola, Nicola;

Oxidopamine



Oxidopamine

• Para-Chloroamphetamine

Chemical compound

over other serotonergic neurotoxins like 5,6-dihydroxytryptamine (5,6-DHT) and 5,7-dihydroxytryptamine (5,7-DHT) in that it is active by systemic administration

Para-Chloroamphetamine



Para-Chloroamphetamine

• Head-twitch response

Head movement in rodents upon 5-HT2A receptor activation

PMID 42414551. Heal, D. J., Metz, A., & Philpot, J. (1985). 5, 7-dihydroxytryptamine lesioning increases both 5-HT-2 mediated behavior and cortical 5-HT-2

Head-twitch response



Head-twitch_response

• 8-OH-DPAT

Pharmaceutical compound

8-hydroxy-2-(dipropylamino)tetralin-induced neuroendocrine responses after 5,7-dihydroxytryptamine-induced denervation of serotonergic neurons". J Pharmacol Exp Ther

8-OH-DPAT



8-OH-DPAT

• Selegiline

Medication

protecting against the serotonergic and noradrenergic neurotoxin 5,7-dihydroxytryptamine (5,7-DHT). Selegiline has also been reported to protect against

Selegiline



Selegiline

• Tryptamine

Metabolite of the amino acid tryptophan

9.68. PMID 2940357. Orikasa S, Sloley BD (1988). "Effects of 5,7-dihydroxytryptamine and 6-hydroxydopamine on head-twitch response induced by serotonin

Tryptamine



Tryptamine

• TMEM155

Protein and gene in humans

B, Buda M, Lewis BD, Pujol JF (September 1975). "Effects of 5,6-dihydroxytryptamine on tyrosine-hydroxylase activity in central catecholaminergic neurons

TMEM155



TMEM155

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Online names & meanings

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